Jonathan K. Watts

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Masad J. DamhaDistinguished James McGill ProfessorPatvirtintas el. paštas mcgill.ca
Anastasia KhvorovaUMASS Medical SchoolPatvirtintas el. paštas umassmed.edu
David CoreyPatvirtintas el. paštas utsouthwestern.edu
Erik SontheimerRNA Therapeutics Institute, UMass Medical SchoolPatvirtintas el. paštas umassmed.edu
Michael P MoazamiPatvirtintas el. paštas paediatrics.ox.ac.uk
Pranathi Meda KrishnamurthyBristol Myers SquibbPatvirtintas el. paštas umassmed.edu
Vivek SharmaUniversity of Massachusetts Chan Med School, USAPatvirtintas el. paštas umassmed.edu
Dimas EcheverriaAssoc Director of Nucleic Acid Chemistry Center, UMass Medical SchoolPatvirtintas el. paštas umassmed.edu
Alexandre J. DebackerPatvirtintas el. paštas natahub.org
Damon (Feng) Wang, PhDNucyrna TherapeuticsPatvirtintas el. paštas nucyrnatx.com
Zexiang ChenPostdoctoral Researcher, UT Southwestern Medical CenterPatvirtintas el. paštas utsouthwestern.edu
Robert BrownPatvirtintas el. paštas umassmed.edu
Aamir MirAssociate Director at Tessera TherapeuticsPatvirtintas el. paštas tesseratx.com
Adam K HedgerGraduate Student, University of Massachusetts Medical SchoolPatvirtintas el. paštas umassmed.edu
Alessandro PomaBiomaterials and Tissue Engineering, Eastman Dental Institute, UCL, London, UKPatvirtintas el. paštas ucl.ac.uk
Miklos MarosfoiBeth Israel Lahey Health, LHMCPatvirtintas el. paštas lahey.org
Keith T. GagnonSouthern Illinois UniversityPatvirtintas el. paštas siu.edu
Julia AltermanUniversity of Massachusetts Medical SchoolPatvirtintas el. paštas umassmed.edu
Matthew HasslerUmass Medical SchoolPatvirtintas el. paštas mail.mcgill.ca
Robert BowserBarrow Neurological InstitutePatvirtintas el. paštas dignityhealth.org

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Jonathan K. Watts

Professor, RNA Therapeutics Institute, UMass Chan Medical School

Patvirtintas el. paštas umassmed.edu - Pagrindinis puslapis

Chemical Biology of Oligonucleotides Nucleic Acid Therapeutics


Pavadinimas Rūšiuoti pagal šaltinius Rūšiuoti pagal metus Rūšiuoti pagal pavadinimą	Cituota Cituota	Metai
The chemical evolution of oligonucleotide therapies of clinical utility A Khvorova, JK Watts Nature biotechnology 35 (3), 238-248, 2017	1012	2017
Chemically modified siRNA: tools and applications JK Watts, GF Deleavey, MJ Damha Drug discovery today 13 (19-20), 842-855, 2008	554	2008
Silencing disease genes in the laboratory and the clinic JK Watts, DR Corey The Journal of pathology 226 (2), 365-379, 2012	525*	2012
Enhancer RNA facilitates NELF release from immediate early genes K Schaukowitch, JY Joo, X Liu, JK Watts, C Martinez, TK Kim Molecular cell 56 (1), 29-42, 2014	447	2014
RNA therapeutics on the rise F Wang, T Zuroske, JK Watts Nature Reviews Drug Discovery 19, 441-442, 2020	208	2020
Synergistic effects between analogs of DNA and RNA improve the potency of siRNA-mediated gene silencing GF Deleavey, JK Watts, T Alain, F Robert, A Kalota, V Aishwarya, ... Nucleic acids research 38 (13), 4547-4557, 2010	123	2010
Energetically important C− H··· F− C pseudohydrogen bonding in water: evidence and application to rational design of oligonucleotides with high binding affinity MY Anzahaee, JK Watts, NR Alla, AW Nicholson, MJ Damha Journal of the American Chemical Society 133 (4), 728-731, 2011	109	2011
Oligonucleotide therapeutics: chemistry, delivery and clinical progress VK Sharma, JK Watts Future medicinal chemistry 7 (16), 2221-2242, 2015	108	2015
2′-Fluoro-4′-thioarabino-modified oligonucleotides: conformational switches linked to siRNA activity JK Watts, N Choubdar, K Sadalapure, F Robert, AS Wahba, J Pelletier, ... Nucleic acids research 35 (5), 1441-1451, 2007	106	2007
The NIH somatic cell genome editing program K Saha, EJ Sontheimer, PJ Brooks, MR Dwinell, CA Gersbach, DR Liu, ... Nature 592 (7853), 195-204, 2021	97	2021
Heavily and fully modified RNAs guide efficient SpyCas9-mediated genome editing A Mir, JF Alterman, MR Hassler, AJ Debacker, E Hudgens, D Echeverria, ... Nature Communications 9, 2641, 2018	96	2018
Suppression of mutant C9orf72 expression by a potent mixed backbone antisense oligonucleotide H Tran, MP Moazami, H Yang, D McKenna-Yasek, CL Douthwright, ... Nature medicine 28 (1), 117-124, 2022	94	2022
Clinical status of duplex RNA JK Watts, DR Corey Bioorganic & medicinal chemistry letters 20 (11), 3203-3207, 2010	91	2010
Chemical modification of siRNA GF Deleavey, JK Watts, MJ Damha Current Protocols in Nucleic Acid Chemistry 39 (1), 16.3. 1-16.3. 22, 2009	89	2009
Differential stability of 2′ F-ANA• RNA and ANA• RNA hybrid duplexes: roles of structure, pseudohydrogen bonding, hydration, ion uptake and flexibility JK Watts, N Martín-Pintado, I Gomez-Pinto, J Schwartzentruber, G Portella, ... Nucleic acids research 38 (7), 2498-2511, 2010	88	2010
Generation of novel hybrid aptamer-molecularly imprinted polymeric nanoparticles A Poma, H Brahmbhatt, HM Pendergraff, JK Watts, NW Turner Wiley, 2015	84	2015
2′ F-Arabinonucleic acids (2′ F-ANA)—History, properties, and new frontiers JK Watts, MJ Damha Canadian Journal of Chemistry 86 (7), 641-656, 2008	77	2008
Studies on the hydrolytic stability of 2′-fluoroarabinonucleic acid (2′ F-ANA) JK Watts, A Katolik, J Viladoms, MJ Damha Organic & biomolecular chemistry 7 (9), 1904-1910, 2009	73	2009
Allele-selective inhibition of ataxin-3 (ATX3) expression by antisense oligomers and duplex RNAs J Hu, KT Gagnon, J Liu, JK Watts, J Syeda-Nawaz, CF Bennett, ... Walter de Gruyter 392 (4), 315-325, 2011	69	2011
Oligonucleotides targeting TCF4 triplet repeat expansion inhibit RNA foci and mis-splicing in Fuchs’ dystrophy J Hu, Z Rong, X Gong, Z Zhou, VK Sharma, C Xing, JK Watts, DR Corey, ... Human molecular genetics 27 (6), 1015-1026, 2018	63	2018

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