Shirley Graham
Shirley Graham
Patvirtintas el. paštas
Structure and mechanism of the CMR complex for CRISPR-mediated antiviral immunity
J Zhang, C Rouillon, M Kerou, J Reeks, K Brugger, S Graham, J Reimann, ...
Molecular cell, 2012
Structural and functional characterization of an archaeal clustered regularly interspaced short palindromic repeat (CRISPR)-associated complex for antiviral defense (CASCADE)
NG Lintner, M Kerou, SK Brumfield, S Graham, H Liu, JH Naismith, ...
Journal of Biological Chemistry 286 (24), 21643-21656, 2011
Two nitridergic peptides are encoded by the gene capability in Drosophila melanogaster
L Kean, W Cazenave, L Costes, KE Broderick, S Graham, VP Pollock, ...
American Journal of Physiology-Regulatory, Integrative and Comparative …, 2002
Structure of the CRISPR interference complex CSM reveals key similarities with cascade
C Rouillon, M Zhou, J Zhang, A Politis, V Beilsten-Edmands, G Cannone, ...
Molecular cell 52 (1), 124-134, 2013
Control of cyclic oligoadenylate synthesis in a type III CRISPR system
C Rouillon, JS Athukoralage, S Graham, S Grüschow, MF White
Elife 7, e36734, 2018
An anti-CRISPR viral ring nuclease subverts type III CRISPR immunity
JS Athukoralage, SA McMahon, C Zhang, S Grüschow, S Graham, ...
Nature 577 (7791), 572-575, 2020
Ring nucleases deactivate type III CRISPR ribonucleases by degrading cyclic oligoadenylate
JS Athukoralage, C Rouillon, S Graham, S Grüschow, MF White
Nature 562 (7726), 277-280, 2018
Molecular Genetic Analysis of V-ATPase Function in Drosophila Melanogaster
JAT Dow, SA Davies, Y Guo, S Graham, ME Finbow, K Kaiser
Journal of Experimental Biology 200 (2), 237-245, 1997
Structure and mechanism of a Type III CRISPR defence DNA nuclease activated by cyclic oligoadenylate
SA McMahon, W Zhu, S Graham, R Rambo, MF White, TM Gloster
Nature communications 11 (1), 500, 2020
Prespacer processing and specific integration in a Type IA CRISPR system
C Rollie, S Graham, C Rouillon, MF White
Nucleic acids research 46 (3), 1007-1020, 2018
Multiple nucleic acid cleavage modes in divergent type III CRISPR systems
J Zhang, S Graham, A Tello, H Liu, MF White
Nucleic acids research 44 (4), 1789-1799, 2016
Cas6 specificity and CRISPR RNA loading in a complex CRISPR-Cas system
RD Sokolowski, S Graham, MF White
Nucleic acids research 42 (10), 6532-6541, 2014
Potent, synergistic inhibition of Staphylococcus aureus upon exposure to a combination of the endopeptidase lysostaphin and the cationic peptide ranalexin
S Graham, PJ Coote
Journal of Antimicrobial Chemotherapy 59 (4), 759-762, 2007
A type III CRISPR ancillary ribonuclease degrades its cyclic oligoadenylate activator
JS Athukoralage, S Graham, S Grüschow, C Rouillon, MF White
Journal of Molecular Biology 431 (15), 2894-2899, 2019
Structure of a dimeric crenarchaeal Cas6 enzyme with an atypical active site for CRISPR RNA processing
J Reeks, RD Sokolowski, S Graham, H Liu, JH Naismith, MF White
Biochemical Journal 452 (2), 223-230, 2013
The dynamic interplay of host and viral enzymes in type III CRISPR-mediated cyclic nucleotide signalling
JS Athukoralage, S Graham, C Rouillon, S Grüschow, CM Czekster, ...
Elife 9, e55852, 2020
Cyclic oligoadenylate signalling mediates Mycobacterium tuberculosis CRISPR defence
S Grüschow, JS Athukoralage, S Graham, T Hoogeboom, MF White
Nucleic acids research 47 (17), 9259-9270, 2019
Global network analysis of drug tolerance, mode of action and virulence in methicillin-resistant S. aureus
IM Overton, S Graham, KA Gould, J Hinds, CH Botting, S Shirran, ...
BMC systems biology 5 (1), 68, 2011
Displacement of the canonical single-stranded DNA-binding protein in the Thermoproteales
S Paytubi, SA McMahon, S Graham, H Liu, CH Botting, KS Makarova, ...
Proceedings of the National Academy of Sciences 109 (7), E398-E405, 2012
The dg2 (for) gene confers a renal phenotype in Drosophila by modulation of cGMP-specific phosphodiesterase
MR MacPherson, KE Broderick, S Graham, JP Day, MD Houslay, ...
Journal of Experimental Biology 207 (16), 2769-2776, 2004
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Straipsniai 1–20