| Structure and mechanism of the CMR complex for CRISPR-mediated antiviral immunity J Zhang, C Rouillon, M Kerou, J Reeks, K Brugger, S Graham, J Reimann, ... Molecular cell, 2012 | 447 | 2012 |
| Structural and functional characterization of an archaeal clustered regularly interspaced short palindromic repeat (CRISPR)-associated complex for antiviral defense (CASCADE) NG Lintner, M Kerou, SK Brumfield, S Graham, H Liu, JH Naismith, ... Journal of Biological Chemistry 286 (24), 21643-21656, 2011 | 329 | 2011 |
| Two nitridergic peptides are encoded by the gene capability in Drosophila melanogaster L Kean, W Cazenave, L Costes, KE Broderick, S Graham, VP Pollock, ... American Journal of Physiology-Regulatory, Integrative and Comparative
, 2002 | 230 | 2002 |
| Structure of the CRISPR interference complex CSM reveals key similarities with cascade C Rouillon, M Zhou, J Zhang, A Politis, V Beilsten-Edmands, G Cannone, ... Molecular cell 52 (1), 124-134, 2013 | 228 | 2013 |
| Control of cyclic oligoadenylate synthesis in a type III CRISPR system C Rouillon, JS Athukoralage, S Graham, S Grüschow, MF White Elife 7, e36734, 2018 | 115 | 2018 |
| An anti-CRISPR viral ring nuclease subverts type III CRISPR immunity JS Athukoralage, SA McMahon, C Zhang, S Grüschow, S Graham, ... Nature 577 (7791), 572-575, 2020 | 111 | 2020 |
| Ring nucleases deactivate type III CRISPR ribonucleases by degrading cyclic oligoadenylate JS Athukoralage, C Rouillon, S Graham, S Grüschow, MF White Nature 562 (7726), 277-280, 2018 | 89 | 2018 |
| Molecular Genetic Analysis of V-ATPase Function in Drosophila Melanogaster JAT Dow, SA Davies, Y Guo, S Graham, ME Finbow, K Kaiser Journal of Experimental Biology 200 (2), 237-245, 1997 | 82 | 1997 |
| Structure and mechanism of a Type III CRISPR defence DNA nuclease activated by cyclic oligoadenylate SA McMahon, W Zhu, S Graham, R Rambo, MF White, TM Gloster Nature communications 11 (1), 500, 2020 | 77 | 2020 |
| Prespacer processing and specific integration in a Type IA CRISPR system C Rollie, S Graham, C Rouillon, MF White Nucleic acids research 46 (3), 1007-1020, 2018 | 74 | 2018 |
| Multiple nucleic acid cleavage modes in divergent type III CRISPR systems J Zhang, S Graham, A Tello, H Liu, MF White Nucleic acids research 44 (4), 1789-1799, 2016 | 73 | 2016 |
| Cas6 specificity and CRISPR RNA loading in a complex CRISPR-Cas system RD Sokolowski, S Graham, MF White Nucleic acids research 42 (10), 6532-6541, 2014 | 61 | 2014 |
| Potent, synergistic inhibition of Staphylococcus aureus upon exposure to a combination of the endopeptidase lysostaphin and the cationic peptide ranalexin S Graham, PJ Coote Journal of Antimicrobial Chemotherapy 59 (4), 759-762, 2007 | 55 | 2007 |
| A type III CRISPR ancillary ribonuclease degrades its cyclic oligoadenylate activator JS Athukoralage, S Graham, S Grüschow, C Rouillon, MF White Journal of Molecular Biology 431 (15), 2894-2899, 2019 | 53 | 2019 |
| Structure of a dimeric crenarchaeal Cas6 enzyme with an atypical active site for CRISPR RNA processing J Reeks, RD Sokolowski, S Graham, H Liu, JH Naismith, MF White Biochemical Journal 452 (2), 223-230, 2013 | 45 | 2013 |
| The dynamic interplay of host and viral enzymes in type III CRISPR-mediated cyclic nucleotide signalling JS Athukoralage, S Graham, C Rouillon, S Grüschow, CM Czekster, ... Elife 9, e55852, 2020 | 43 | 2020 |
| Cyclic oligoadenylate signalling mediates Mycobacterium tuberculosis CRISPR defence S Grüschow, JS Athukoralage, S Graham, T Hoogeboom, MF White Nucleic acids research 47 (17), 9259-9270, 2019 | 41 | 2019 |
| Global network analysis of drug tolerance, mode of action and virulence in methicillin-resistant S. aureus IM Overton, S Graham, KA Gould, J Hinds, CH Botting, S Shirran, ... BMC systems biology 5 (1), 68, 2011 | 39 | 2011 |
| Displacement of the canonical single-stranded DNA-binding protein in the Thermoproteales S Paytubi, SA McMahon, S Graham, H Liu, CH Botting, KS Makarova, ... Proceedings of the National Academy of Sciences 109 (7), E398-E405, 2012 | 34 | 2012 |
| The dg2 (for) gene confers a renal phenotype in Drosophila by modulation of cGMP-specific phosphodiesterase MR MacPherson, KE Broderick, S Graham, JP Day, MD Houslay, ... Journal of Experimental Biology 207 (16), 2769-2776, 2004 | 34 | 2004 |
