| A SARS-CoV-2 protein interaction map reveals targets for drug repurposing DE Gordon, GM Jang, M Bouhaddou, J Xu, K Obernier, KM White, ... Nature 583 (7816), 459-468, 2020 | 4364 | 2020 |
| CIS is a potent checkpoint in NK cell–mediated tumor immunity RB Delconte, TB Kolesnik, LF Dagley, J Rautela, W Shi, EM Putz, ... Nature immunology 17 (7), 816-824, 2016 | 337 | 2016 |
| Comparative flavivirus-host protein interaction mapping reveals mechanisms of dengue and Zika virus pathogenesis PS Shah, N Link, GM Jang, PP Sharp, T Zhu, DL Swaney, JR Johnson, ... Cell 175 (7), 1931-1945. e18, 2018 | 274 | 2018 |
| BET bromodomain inhibitors: a patent review JM Garnier, PP Sharp, CJ Burns Expert opinion on therapeutic patents 24 (2), 185-199, 2014 | 140 | 2014 |
| BET inhibitors induce apoptosis through a MYC independent mechanism and synergise with CDK inhibitors to kill osteosarcoma cells EK Baker, S Taylor, A Gupte, PP Sharp, M Walia, NC Walsh, ... Scientific reports 5 (1), 10120, 2015 | 124 | 2015 |
| A RIPK2 inhibitor delays NOD signalling events yet prevents inflammatory cytokine production U Nachbur, CA Stafford, A Bankovacki, Y Zhan, LM Lindqvist, BK Fiil, ... Nature communications 6 (1), 6442, 2015 | 124 | 2015 |
| Consecutive Gold(I)-Catalyzed Cyclization Reactions of o-(Buta-1,3-diyn-1-yl-)-Substituted N-Aryl Ureas: A One-Pot Synthesis of Pyrimido[1,6-a]indol-1(2H)-ones … PP Sharp, MG Banwell, J Renner, K Lohmann, AC Willis Organic letters 15 (11), 2616-2619, 2013 | 62 | 2013 |
| A small molecule interacts with VDAC2 to block mouse BAK-driven apoptosis MF van Delft, S Chappaz, Y Khakham, CT Bui, MA Debrincat, KN Lowes, ... Nature chemical biology 15 (11), 1057-1066, 2019 | 37 | 2019 |
| BET inhibition represses miR17-92 to drive BIM-initiated apoptosis of normal and transformed hematopoietic cells Z Xu, PP Sharp, Y Yao, D Segal, CH Ang, SL Khaw, BJ Aubrey, J Gong, ... Leukemia 30 (7), 1531-1541, 2016 | 36 | 2016 |
| Dichlorocarbene adducts of alkyl enol ethers as precursors to furans: application to a total synthesis of the furanosesquiterpene (±)-pallescensin A JS Foot, AT Phillis, PP Sharp, AC Willis, MG Banwell Tetrahedron letters 47 (38), 6817-6820, 2006 | 35 | 2006 |
| Design, synthesis, and biological activity of 1, 2, 3-triazolobenzodiazepine BET bromodomain inhibitors PP Sharp, JM Garnier, T Hatfaludi, Z Xu, D Segal, KE Jarman, H Jousset, ... ACS Medicinal Chemistry Letters 8 (12), 1298-1303, 2017 | 28 | 2017 |
| Synthesis of rhamnosylated arginine glycopeptides and determination of the glycosidic linkage in bacterial elongation factor P S Wang, L Corcilius, PP Sharp, A Rajkovic, M Ibba, BL Parker, RJ Payne Chemical Science 8 (3), 2296-2302, 2017 | 27 | 2017 |
| Evaluation of functional groups as acetyl-lysine mimetics for BET bromodomain inhibition PP Sharp, JM Garnier, DCS Huang, CJ Burns MedChemComm 5 (12), 1834-1842, 2014 | 27 | 2014 |
| Simplified silvestrol analogues with potent cytotoxic activity BC Hawkins, LM Lindqvist, D Nhu, PP Sharp, D Segal, AK Powell, ... ChemMedChem 9 (7), 1556-1566, 2014 | 24 | 2014 |
| Inhibitors of eukaryotic translational machinery as therapeutic agents A Fan, PP Sharp Journal of Medicinal Chemistry 64 (5), 2436-2465, 2021 | 18 | 2021 |
| Florida initiative for quality cancer care: improvements in breast cancer quality indicators during a 3-year interval C Laronga, JE Gray, EM Siegel, JH Lee, WJ Fulp, M Fletcher, F Schreiber, ... Journal of the American College of Surgeons 219 (4), 638-645. e1, 2014 | 18 | 2014 |
| Total Syntheses of the 3H-Pyrrolo[2,3-c]quinolone-Containing Alkaloids Marinoquinolines A–F, K, and Aplidiopsamine A Using a Palladium-Catalyzed Ullmann … B Bolte, CS Bryan, PP Sharp, S Sayyahi, C Rihouey, A Kendrick, P Lan, ... The Journal of Organic Chemistry 85 (2), 650-663, 2019 | 16 | 2019 |
| Mechanistic Studies on the Base-Promoted Conversion of Alkoxy-Substituted, Ring-Fused gem-Dihalocyclopropanes into Furans: Evidence for a Process Involving … PP Sharp, J Mikusek, J Ho, EH Krenske, MG Banwell, ML Coote, JS Ward, ... The Journal of Organic Chemistry 83 (22), 13678-13690, 2018 | 9 | 2018 |
| Signal peptide mimicry primes Sec61 for client-selective inhibition S Rehan, D Tranter, PP Sharp, GB Craven, E Lowe, JL Anderl, ... Nature Chemical Biology 19 (9), 1054-1062, 2023 | 8 | 2023 |
| Synthesis of a GlcNAcylated arginine building block for the solid phase synthesis of death domain glycopeptide fragments S Wang, L Corcilius, PP Sharp, RJ Payne Bioorganic & Medicinal Chemistry 25 (11), 2895-2900, 2017 | 8 | 2017 |
