| MiRNA-21 silencing mediated by tumor-targeted nanoparticles combined with sunitinib: A new multimodal gene therapy approach for glioblastoma PM Costa, AL Cardoso, C Custódia, P Cunha, LP de Almeida, ... Journal of Controlled Release 207, 31-39, 2015 | 190 | 2015 |
| Translocation of LRP1 targeted carbon nanotubes of different diameters across the blood–brain barrier in vitro and in vivo H Kafa, JTW Wang, N Rubio, R Klippstein, PM Costa, HAFM Hassan, ... Journal of Controlled Release 225, 217-229, 2016 | 119 | 2016 |
| Tumor-targeted chlorotoxin-coupled nanoparticles for nucleic acid delivery to glioblastoma cells: a promising system for glioblastoma treatment PM Costa, AL Cardoso, LS Mendonça, A Serani, C Custódia, ... Molecular Therapy-Nucleic Acids 2, 2013 | 116 | 2013 |
| Intravenous administration of brain-targeted stable nucleic acid lipid particles alleviates Machado-Joseph disease neurological phenotype M Conceição, L Mendonça, C Nóbrega, C Gomes, P Costa, H Hirai, ... Biomaterials 82, 124-137, 2016 | 99 | 2016 |
| MicroRNA-21 silencing enhances the cytotoxic effect of the antiangiogenic drug sunitinib in glioblastoma PM Costa, AL Cardoso, C Nobrega, LF Pereira de Almeida, JN Bruce, ... Human molecular genetics 22 (5), 904-918, 2013 | 94 | 2013 |
| MicroRNAs as molecular targets for cancer therapy: on the modulation of microRNA expression PM Costa, MC Pedroso de Lima Pharmaceuticals 6 (10), 1195-1220, 2013 | 91 | 2013 |
| Tf-lipoplex-mediated c-Jun silencing improves neuronal survival following excitotoxic damage in vivo ALC Cardoso, P Costa, LP De Almeida, S Simoes, N Plesnila, C Culmsee, ... Journal of Controlled Release 142 (3), 392-403, 2010 | 55 | 2010 |
| Synthesis of double-clickable functionalised graphene oxide for biological applications KC Mei, N Rubio, PM Costa, H Kafa, V Abbate, F Festy, SS Bansal, ... Chemical communications 51 (81), 14981-14984, 2015 | 50 | 2015 |
| MicroRNAs in glioblastoma: role in pathogenesis and opportunities for targeted therapies P M Costa, A L Cardoso, M Mano, M C Pedroso de Lima CNS & Neurological Disorders-Drug Targets (Formerly Current Drug Targets-CNS …, 2015 | 43 | 2015 |
| Solvent-free click-mechanochemistry for the preparation of cancer cell targeting graphene oxide N Rubio, KC Mei, R Klippstein, PM Costa, N Hodgins, JTW Wang, F Festy, ... ACS applied materials & interfaces 7 (34), 18920-18923, 2015 | 36 | 2015 |
| Organic solvent-free, one-step engineering of graphene-based magnetic-responsive hybrids using design of experiment-driven mechanochemistry KC Mei, Y Guo, J Bai, PM Costa, H Kafa, A Protti, RC Hider, KT Al-Jamal ACS applied materials & interfaces 7 (26), 14176-14181, 2015 | 36 | 2015 |
| PDGF-B-mediated downregulation of miR-21: new insights into PDGF signaling in glioblastoma PM Costa, AL Cardoso, LF Pereira de Almeida, JN Bruce, P Canoll, ... Human molecular genetics 21 (23), 5118-5130, 2012 | 30 | 2012 |
| Safety profile of the intravenous administration of brain-targeted stable nucleic acid lipid particles M Conceição, L Mendonça, C Nóbrega, C Gomes, P Costa, H Hirai, ... Data in brief 6, 700-705, 2016 | 12 | 2016 |
| Viral and non-viral gene therapy for glioblastoma: new insights into the treatment of malignant brain tumors PM Costa, MCP de Lima J Genet Syndr Gene Ther 4 (7), 161, 2013 | 6 | 2013 |
| MicroRNA modulation renders glioblastoma cells sensitive to chemotherapy PP Cunha, P Costa, R Costa, C Custodia, R Branco, CM Morais, ... EUROPEAN JOURNAL OF CLINICAL INVESTIGATION 45, 72-73, 2015 | | 2015 |
| MIR-21 AND MIR-128 DEREGULATION IN GLIOBLASTOMA: EFFECT OF MIRNA MODULATION ON CELL VIABILITY P Costa, ALC Cardoso, LP de Almeida, MC de Lima, P Canoll, J Bruce NEURO-ONCOLOGY 12, 9-10, 2010 | | 2010 |
| Tf-lipoplex-mediated c-Jun knockdown results in neuroprotection following excitotoxic injury in the mouse brain A Cardoso, P Costa, S Simoes, L Almeida, N Plesnila, C Culmsee, ... HUMAN GENE THERAPY 19 (10), 1127-1128, 2008 | | 2008 |
Luis Pereira de AlmeidaUniversity of Coimbra, CNC - Center for Neuroscience and Cell Biology & Faculty of Pharmacy & CIBBVerified email at cnc.uc.pt
