| Evidence that BCL-2 represses apoptosis by regulating endoplasmic reticulum-associated Ca2+ fluxes. M Lam, G Dubyak, L Chen, G Nunez, RL Miesfeld, CW Distelhorst Proceedings of the National Academy of Sciences 91 (14), 6569-6573, 1994 | 895 | 1994 |
| Photodynamic therapy-induced apoptosis in epidermoid carcinoma cells: reactive oxygen species and mitochondrial inner membrane permeabilization M Lam, NL Oleinick, AL Nieminen Journal of Biological Chemistry 276 (50), 47379-47386, 2001 | 403 | 2001 |
| Maintenance of calcium homeostasis in the endoplasmic reticulum by Bcl-2 H He, M Lam, TS McCormick, CW Distelhorst The Journal of cell biology 138 (6), 1219-1228, 1997 | 401 | 1997 |
| The Artificial Sweetener Splenda Promotes Gut Proteobacteria, Dysbiosis, and Myeloperoxidase Reactivity in Crohn’s Disease–Like Ileitis A Rodriguez-Palacios, A Harding, P Menghini, C Himmelman, M Retuerto, ... Inflammatory bowel diseases 24 (5), 1005-1020, 2018 | 189 | 2018 |
| Domain-dependent photodamage to Bcl-2: A membrane anchorage region is needed to form the target of phthalocyanine photosensitization J Usuda, S Chiu, ES Murphy, M Lam, AL Nieminen, NL Oleinick Journal of Biological Chemistry 278 (3), 2021-2029, 2003 | 158 | 2003 |
| Bcl-2 inhibits hydrogen peroxide-induced ER Ca2+ pool depletion. CW Distelhorst, M Lam, TS McCormick Oncogene 12 (10), 2051-2055, 1996 | 153 | 1996 |
| Induction of Ca2+-driven apoptosis in chronic lymphocytic leukemia cells by peptide-mediated disruption of Bcl-2–IP3 receptor interaction F Zhong, MW Harr, G Bultynck, G Monaco, JB Parys, H De Smedt, ... Blood, The Journal of the American Society of Hematology 117 (10), 2924-2934, 2011 | 143 | 2011 |
| Effect of glucocorticosteroid treatment on intracellular calcium homeostasis in mouse lymphoma cells. M Lam, G Dubyak, CW Distelhorst Molecular Endocrinology 7 (5), 686-693, 1993 | 142 | 1993 |
| Fluorescence resonance energy transfer reveals a binding site of a photosensitizer for photodynamic therapy RL Morris, K Azizuddin, M Lam, J Berlin, AL Nieminen, ME Kenney, ... Cancer research 63 (17), 5194-5197, 2003 | 127 | 2003 |
| Structural factors and mechanisms underlying the improved photodynamic cell killing with silicon phthalocyanine photosensitizers directed to lysosomes versus mitochondria ME Rodriguez, P Zhang, K Azizuddin, GB Delos Santos, S Chiu, L Xue, ... Photochemistry and Photobiology 85 (5), 1189-1200, 2009 | 106 | 2009 |
| Promotion of Photodynamic Therapy‐Induced Apoptosis by the Mitochondrial Protein Smac/DIABLO: Dependence on Bax¶ J Usuda, S Chiu, K Azizuddin, L Xue, M Lam, AL Nieminen, NL Oleinick Photochemistry and photobiology 76 (2), 217-223, 2002 | 99 | 2002 |
| Glucocorticoid elevation of dexamethasone-induced gene 2 (Dig2/RTP801/REDD1) protein mediates autophagy in lymphocytes JK Molitoris, KS McColl, S Swerdlow, M Matsuyama, M Lam, TH Finkel, ... Journal of Biological Chemistry 286 (34), 30181-30189, 2011 | 97 | 2011 |
| Regulation of Bcl-xl channel activity by calcium M Lam, MB Bhat, G Nunez, J Ma, CW Distelhorst Journal of Biological Chemistry 273 (28), 17307-17310, 1998 | 80 | 1998 |
| Apoptosis inhibition by Bcl-2 gives way to autophagy in glucocorticoid-treated lymphocytes S Swerdlow, K McColl, Y Rong, M Lam, A Gupta, CW Distelhorst Autophagy 4 (5), 612-620, 2008 | 71 | 2008 |
| Photodynamic Therapy with Pc 4 Induces Apoptosis of Candida albicans M Lam, PC Jou, AA Lattif, Y Lee, CL Malbasa, PK Mukherjee, NL Oleinick, ... Photochemistry and photobiology 87 (4), 904-909, 2011 | 67 | 2011 |
| Phthalocyanine 4 photodynamic therapy-induced apoptosis of mouse L5178Y-R cells results from a delayed but extensive release of cytochrome c from mitochondria SM Chiu, HH Evans, M Lam, AL Nieminen, NL Oleinick Cancer letters 165 (1), 51-58, 2001 | 59 | 2001 |
| Targeting of mitochondria by 10-N-alkyl acridine orange analogues: role of alkyl chain length in determining cellular uptake and localization ME Rodriguez, K Azizuddin, P Zhang, S Chiu, M Lam, ME Kenney, ... Mitochondrion 8 (3), 237-246, 2008 | 54 | 2008 |
| PEGylated dendrimers as drug delivery vehicles for the photosensitizer silicon phthalocyanine Pc 4 for candidal infections MA Hutnick, S Ahsanuddin, L Guan, M Lam, ED Baron, JK Pokorski Biomacromolecules 18 (2), 379-385, 2017 | 48 | 2017 |
| A requirement for bid for induction of apoptosis by photodynamic therapy with a lysosome‐but not a mitochondrion‐targeted photosensitizer S Chiu, L Xue, M Lam, ME Rodriguez, P Zhang, ME Kenney, AL Nieminen, ... Photochemistry and photobiology 86 (5), 1161-1173, 2010 | 45 | 2010 |
| Neutralization of IL-1α ameliorates Crohn’s disease-like ileitis by functional alterations of the gut microbiome P Menghini, D Corridoni, LF Buttó, A Osme, S Shivaswamy, M Lam, ... Proceedings of the National Academy of Sciences 116 (52), 26717-26726, 2019 | 44 | 2019 |
