Wei Li
Wei Li
Children's National Hospital, George Washington University
Patvirtintas el. paštas - Pagrindinis puslapis
MAGeCK enables robust identification of essential genes from genome-scale CRISPR/Cas9 knockout screens
W Li, H Xu, T Xiao, L Cong, MI Love, F Zhang, RA Irizarry, JS Liu, ...
Genome Biology 15 (554), 2014
Genomic correlates of response to immune checkpoint therapies in clear cell renal cell carcinoma
D Miao, CA Margolis, W Gao, MH Voss, W Li, DJ Martini, C Norton, ...
Science 359 (6377), 801-806, 2018
Bioconda: sustainable and comprehensive software distribution for the life sciences
B Grüning, R Dale, A Sjödin, BA Chapman, J Rowe, CH Tomkins-Tinch, ...
Nature methods 15 (7), 475-476, 2018
Sequence determinants of improved CRISPR sgRNA design
H Xu, T Xiao, CH Chen, W Li, CA Meyer, Q Wu, D Wu, L Cong, F Zhang, ...
Genome research 25 (8), 1147-1157, 2015
Genome-scale deletion screening of human long non-coding RNAs using a paired-guide RNA CRISPR-Cas9 library
S Zhu, W Li, J Liu, CH Chen, Q Liao, P Xu, H Xu, T Xiao, Z Cao, J Peng, ...
Nature biotechnology 34 (12), 1279-1286, 2016
Overcoming Therapeutic Resistance in HER2-Positive Breast Cancers with CDK4/6 Inhibitors
S Goel, Q Wang, AC Watt, SM Tolaney, DA Dillon, W Li, S Ramm, ...
Cancer cell 29 (3), 255-269, 2016
Quality control, modeling, and visualization of CRISPR screens with MAGeCK-VISPR
W Li, J Köster, H Xu, CH Chen, T Xiao, JS Liu, M Brown, XS Liu
Genome biology 16 (1), 1-13, 2015
High-content CRISPR screening
C Bock, P Datlinger, F Chardon, MA Coelho, MB Dong, KA Lawson, T Lu, ...
Nature Reviews Methods Primers 2 (1), 1-23, 2022
Genome-wide CRISPR screen identifies HNRNPL as a prostate cancer dependency regulating RNA splicing
T Fei, Y Chen, T Xiao, W Li, L Cato, P Zhang, MB Cotter, M Bowden, ...
Proceedings of the National Academy of Sciences 114 (26), E5207-E5215, 2017
Integrative analysis of pooled CRISPR genetic screens using MAGeCKFlute
B Wang, M Wang, W Zhang, T Xiao, CH Chen, A Wu, F Wu, N Traugh, ...
Nature protocols 14 (3), 756-780, 2019
Allele-specific chromatin recruitment and therapeutic vulnerabilities of ESR1 activating mutations
R Jeselsohn, JS Bergholz, M Pun, MI Cornwell, W Liu, A Nardone, T Xiao, ...
Cancer cell 33 (2), 173-186. e5, 2018
Isolasso: a lasso regression approach to RNA-seq based transcriptome assembly
W Li, J Feng, T Jiang
Research in Computational Molecular Biology, 168-188, 2011
ARv7 Represses Tumor-Suppressor Genes in Castration-Resistant Prostate Cancer
L Cato, J de Tribolet-Hardy, I Lee, J T. Rottenberg, I Coleman, D Melchers, ...
Cancer Cell 35 (3), 401-413, 2019
RAS/MAPK activation drives resistance to Smo inhibition, metastasis, and tumor evolution in Shh pathway–dependent tumors
X Zhao, T Ponomaryov, KJ Ornell, P Zhou, SK Dabral, E Pak, W Li, ...
Cancer research 75 (17), 3623-3635, 2015
Inactivation of the PBRM1 tumor suppressor gene amplifies the HIF-response in VHL−/− clear cell renal carcinoma
W Gao, W Li, T Xiao, XS Liu, WG Kaelin
Proceedings of the National Academy of Sciences 114 (5), 1027-1032, 2017
Synthetic lethal and resistance interactions with BET bromodomain inhibitors in triple-negative breast cancer
S Shu, HJ Wu, YG Jennifer, R Zeid, IS Harris, B Jovanović, K Murphy, ...
Molecular cell 78 (6), 1096-1113. e8, 2020
Transcriptome Assembly and Isoform Expression Level Estimation from Biased RNA-Seq Reads
W Li, T Jiang
Bioinformatics, 2012
In vivo CRISPR screens identify the E3 ligase Cop1 as a modulator of macrophage infiltration and cancer immunotherapy target
X Wang, C Tokheim, SS Gu, B Wang, Q Tang, Y Li, N Traugh, Z Zeng, ...
Cell 184 (21), 5357-5374. e22, 2021
MethylPurify: tumor purity deconvolution and differential methylation detection from single tumor DNA methylomes
X Zheng, Q Zhao, HJ Wu, W Li, H Wang, CA Meyer, QA Qin, H Xu, C Zang, ...
Genome biology 15 (7), 1-13, 2014
Inference of isoforms from short sequence reads
J Feng, W Li, T Jiang
Journal of computational biology 18 (3), 305-321, 2011
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Straipsniai 1–20