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Bence Hegyi
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Metabolic maturation media improve physiological function of human iPSC-derived cardiomyocytes
DAM Feyen, WL McKeithan, AAN Bruyneel, S Spiering, L Hörmann, ...
Cell reports 32 (3), 2020
2662020
CaMKII signaling in heart diseases: emerging role in diabetic cardiomyopathy
B Hegyi, DM Bers, J Bossuyt
Journal of Molecular and Cellular Cardiology 127, 246-259, 2019
1142019
KCNJ15/Kir4.2 couples with polyamines to sense weak extracellular electric fields in galvanotaxis
K Nakajima, K Zhu, YH Sun, B Hegyi, Q Zeng, CJ Murphy, JV Small, ...
Nature communications 6 (1), 8532, 2015
1062015
Dynamics of the late Na+ current during cardiac action potential and its contribution to afterdepolarizations
B Horvath, T Banyasz, Z Jian, B Hegyi, K Kistamas, PP Nanasi, LT Izu, ...
Journal of molecular and cellular cardiology 64, 59-68, 2013
1022013
Complex electrophysiological remodeling in postinfarction ischemic heart failure
B Hegyi, J Bossuyt, LG Griffiths, R Shimkunas, Z Coulibaly, Z Jian, ...
Proceedings of the National Academy of Sciences 115 (13), E3036-E3044, 2018
882018
β-adrenergic regulation of late Na+ current during cardiac action potential is mediated by both PKA and CaMKII
B Hegyi, T Bányász, LT Izu, L Belardinelli, DM Bers, Y Chen-Izu
Journal of molecular and cellular cardiology 123, 168-179, 2018
692018
Contribution of ion currents to beat-to-beat variability of action potential duration in canine ventricular myocytes
N Szentandrássy, K Kistamás, B Hegyi, B Horváth, F Ruzsnavszky, ...
Pflügers Archiv-European Journal of Physiology 467, 1431-1443, 2015
622015
Hyperglycemia regulates cardiac K+ channels via O-GlcNAc-CaMKII and NOX2-ROS-PKC pathways
B Hegyi, JM Borst, LRJ Bailey, EY Shen, AJ Lucena, MF Navedo, ...
Basic research in cardiology 115, 1-19, 2020
562020
CaMKII serine 280 O-GlcNAcylation links diabetic hyperglycemia to proarrhythmia
B Hegyi, A Fasoli, CY Ko, BW Van, CC Alim, EY Shen, MM Ciccozzi, ...
Circulation research 129 (1), 98-113, 2021
492021
Cardiomyocyte Na+ and Ca2+ mishandling drives vicious cycle involving CaMKII, ROS, and ryanodine receptors
B Hegyi, RP Pölönen, KT Hellgren, CY Ko, KS Ginsburg, J Bossuyt, ...
Basic research in cardiology 116, 1-16, 2021
452021
KN-93 inhibits IKr in mammalian cardiomyocytes
B Hegyi, Y Chen-Izu, Z Jian, R Shimkunas, LT Izu, T Banyasz
Journal of molecular and cellular cardiology 89, 173-176, 2015
402015
Empagliflozin Reverses Late Na+ Current Enhancement and Cardiomyocyte Proarrhythmia in a Translational Murine Model of Heart Failure With Preserved …
B Hegyi, J Mira Hernandez, EY Shen, NR Habibi, J Bossuyt, DM Bers
Circulation 145 (13), 1029-1031, 2022
372022
Altered repolarization reserve in failing rabbit ventricular myocytes: calcium and β-adrenergic effects on delayed-and inward-rectifier potassium currents
B Hegyi, J Bossuyt, KS Ginsburg, LM Mendoza, L Talken, WT Ferrier, ...
Circulation: Arrhythmia and Electrophysiology 11 (2), e005852, 2018
372018
Enhanced depolarization drive in failing rabbit ventricular myocytes: calcium-dependent and β-adrenergic effects on late sodium, L-type calcium, and sodium-calcium exchange …
B Hegyi, S Morotti, C Liu, KS Ginsburg, J Bossuyt, L Belardinelli, LT Izu, ...
Circulation: Arrhythmia and Electrophysiology 12 (3), e007061, 2019
342019
Sarcolemmal Ca2+-entry through L-type Ca2+ channels controls the profile of Ca2+-activated Cl− current in canine ventricular myocytes
B Horváth, K Váczi, B Hegyi, M Gönczi, B Dienes, K Kistamás, T Bányász, ...
Journal of molecular and cellular cardiology 97, 125-139, 2016
322016
Hypermuscular mice with mutation in the myostatin gene display altered calcium signalling
D Bodnár, N Geyer, O Ruzsnavszky, T Oláh, B Hegyi, M Sztretye, J Fodor, ...
The Journal of physiology 592 (6), 1353-1365, 2014
322014
Quantitative cross-species translators of cardiac myocyte electrophysiology: Model training, experimental validation, and applications
S Morotti, C Liu, B Hegyi, H Ni, A Fogli Iseppe, L Wang, M Pritoni, ...
Science Advances 7 (47), eabg0927, 2021
302021
The Janus face of adenosine: antiarrhythmic and proarrhythmic actions
A Jozsef Szentmiklosi, Z Galajda, A Cseppento, R Gesztelyi, Z Susán, ...
Current Pharmaceutical Design 21 (8), 965-976, 2015
302015
Changes in intracellular calcium concentration influence beat-to-beat variability of action potential duration in canine ventricular myocytes
K Kistamas, N Szentandrassy, B Hegyi, K Vaczi, F Ruzsnavszky, ...
J. Physiol. Pharmacol 66 (1), 73-81, 2015
302015
Two-hit mechanism of cardiac arrhythmias in diabetic hyperglycaemia: reduced repolarization reserve, neurohormonal stimulation, and heart failure exacerbate susceptibility
B Hegyi, CY Ko, J Bossuyt, DM Bers
Cardiovascular research 117 (14), 2781-2793, 2021
262021
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