Priming in the Type IF CRISPR-Cas system triggers strand-independent spacer acquisition, bi-directionally from the primed protospacer C Richter, RL Dy, RE McKenzie, BNJ Watson, C Taylor, JT Chang, ... Nucleic acids research 42 (13), 8516-8526, 2014 | 200 | 2014 |
SdhE is a conserved protein required for flavinylation of succinate dehydrogenase in bacteria MB McNeil, JS Clulow, NM Wilf, GPC Salmond, PC Fineran Journal of Biological Chemistry 287 (22), 18418-18428, 2012 | 75 | 2012 |
PigS and PigP Regulate Prodigiosin Biosynthesis in Serratia via Differential Control of Divergent Operons, Which Include Predicted Transporters of Sulfur
T Gristwood, MB McNeil, JS Clulow, GPC Salmond, PC Fineran Journal of bacteriology 193 (5), 1076-1085, 2011 | 61 | 2011 |
Utilization of CRISPR Interference To Validate MmpL3 as a Drug Target in Mycobacterium tuberculosis MB McNeil, GM Cook Antimicrobial agents and chemotherapy 63 (8), e00629-19, 2019 | 36 | 2019 |
In Vitro Isolation and Characterization of Oxazolidinone-Resistant Mycobacterium tuberculosis MB McNeil, DD Dennison, CD Shelton, T Parish Antimicrobial Agents and Chemotherapy 61 (10), e01296-17, 2017 | 34 | 2017 |
The succinate dehydrogenase assembly factor, SdhE, is required for the flavinylation and activation of fumarate reductase in bacteria MB McNeil, HG Hampton, KJ Hards, BNJ Watson, GM Cook, PC Fineran FEBS letters 588 (3), 414-421, 2014 | 31 | 2014 |
Mutations in MmpL3 alter membrane potential, hydrophobicity and antibiotic susceptibility in Mycobacterium smegmatis MB McNeil, D Dennison, T Parish Microbiology 163 (7), 1065-1070, 2017 | 28 | 2017 |
Discovery of a cofactor-independent inhibitor of Mycobacterium tuberculosis InhA Y Xia, Y Zhou, DS Carter, MB McNeil, W Choi, J Halladay, PW Berry, ... Life Science Alliance 1 (3), 2018 | 27 | 2018 |
CRISPR-Cas gene-editing reveals RsmA and RsmC act through FlhDC to repress the SdhE flavinylation factor and control motility and prodigiosin production in Serratia HG Hampton, MB McNeil, TJ Paterson, B Ney, NR Williamson, ... Microbiology 162 (6), 1047, 2016 | 26 | 2016 |
Prokaryotic assembly factors for the attachment of flavin to complex II MB McNeil, PC Fineran Biochimica et Biophysica Acta (BBA)-Bioenergetics 1827 (5), 637-647, 2013 | 25 | 2013 |
MmpL3 inhibitors as antituberculosis drugs M Shao, M McNeil, GM Cook, X Lu European Journal of Medicinal Chemistry 200, 112390, 2020 | 24 | 2020 |
The conserved RGxxE motif of the bacterial FAD assembly factor SdhE is required for succinate dehydrogenase flavinylation and activity MB McNeil, PC Fineran Biochemistry 52 (43), 7628-7640, 2013 | 21 | 2013 |
Draft Genome Sequence of Serratia sp. Strain ATCC 39006, a Model Bacterium for Analysis of the Biosynthesis and Regulation of Prodigiosin, a Carbapenem, and
PC Fineran, MC Iglesias Cans, JP Ramsay, NM Wilf, D Cossyleon, ... Genome announcements 1 (6), e01039-13, 2013 | 20 | 2013 |
Two for the price of one: Attacking the energetic-metabolic hub of mycobacteria to produce new chemotherapeutic agents K Hards, C Adolph, LK Harold, MB McNeil, CY Cheung, A Jinich, ... Progress in Biophysics and Molecular Biology 152, 35-44, 2020 | 18 | 2020 |
Cell wall inhibitors increase the accumulation of rifampicin in Mycobacterium tuberculosis MB McNeil, S Chettiar, D Awasthi, T Parish Access Microbiology 1 (1), 2019 | 17 | 2019 |
Transcriptional Inhibition of the F1F0-Type ATP Synthase Has Bactericidal Consequences on the Viability of Mycobacteria MB McNeil, HWK Ryburn, LK Harold, JF Tirados, GM Cook Antimicrobial agents and chemotherapy 64 (8), e00492-20, 2020 | 15 | 2020 |
CRISPR interference identifies vulnerable cellular pathways with bactericidal phenotypes in Mycobacterium tuberculosis MB McNeil, LM Keighley, JR Cook, CY Cheung, GM Cook Molecular microbiology 116 (4), 1033-1043, 2021 | 14 | 2021 |
Multiple mutations in Mycobacterium tuberculosis MmpL3 increase resistance to MmpL3 inhibitors MB McNeil, T OMalley, D Dennison, CD Shelton, B Sunde, T Parish Msphere 5 (5), e00985-20, 2020 | 12* | 2020 |
Efficacy and improved resistance potential of a cofactor-independent InhA inhibitor of Mycobacterium tuberculosis in the C3HeB/FeJ mouse model GT Robertson, VA Ektnitphong, MS Scherman, MB McNeil, D Dennison, ... Antimicrobial Agents and Chemotherapy 63 (4), e02071-18, 2019 | 11 | 2019 |
YgfX (CptA) is a multimeric membrane protein that interacts with the succinate dehydrogenase assembly factor SdhE (YgfY) MB McNeil, MC Iglesias-Cans, JS Clulow, PC Fineran Microbiology 159 (Pt_7), 1352-1365, 2013 | 11 | 2013 |