Yong Zhou
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Membrane potential modulates plasma membrane phospholipid dynamics and K-Ras signaling
Y Zhou, CO Wong, K Cho, D Van Der Hoeven, H Liang, DP Thakur, J Luo, ...
Science 349 (6250), 873-876, 2015
Inhibition of RAS function through targeting an allosteric regulatory site
R Spencer-Smith, A Koide, Y Zhou, RR Eguchi, F Sha, P Gajwani, ...
Nature chemical biology 13 (1), 62-68, 2017
Lipid-sorting specificity encoded in K-Ras membrane anchor regulates signal output
Y Zhou, P Prakash, H Liang, KJ Cho, AA Gorfe, JF Hancock
Cell 168 (1), 239-251. e16, 2017
Ras nanoclusters: Versatile lipid-based signaling platforms
Y Zhou, JF Hancock
Biochimica et Biophysica Acta (BBA)-Molecular Cell Research 1853 (4), 841-849, 2015
Tumor induces muscle wasting in mice through releasing extracellular Hsp70 and Hsp90
G Zhang, Z Liu, H Ding, Y Zhou, HA Doan, KWT Sin, ZJ Zhu, R Flores, ...
Nature communications 8 (1), 589, 2017
NSAID injury to the gastrointestinal tract: evidence that NSAIDs interact with phospholipids to weaken the hydrophobic surface barrier and induce the formation of unstable …
LM Lichtenberger, Y Zhou, EJ Dial, RM Raphael
journal of pharmacy and pharmacology 58 (11), 1421-1428, 2006
Signal integration by lipid-mediated spatial cross talk between Ras nanoclusters
Y Zhou, H Liang, T Rodkey, N Ariotti, RG Parton, JF Hancock
Molecular and cellular biology 34 (5), 862-876, 2014
Insight into NSAID-induced membrane alterations, pathogenesis and therapeutics: characterization of interaction of NSAIDs with phosphatidylcholine
LM Lichtenberger, Y Zhou, V Jayaraman, JR Doyen, RG O'Neil, EJ Dial, ...
Biochimica et Biophysica Acta (BBA)-Molecular and Cell Biology of Lipids …, 2012
Solution pH alters mechanical and electrical properties of phosphatidylcholine membranes: relation between interfacial electrostatics, intramembrane potential, and bending …
Y Zhou, RM Raphael
Biophysical journal 92 (7), 2451-2462, 2007
Single-molecule analysis reveals self assembly and nanoscale segregation of two distinct cavin subcomplexes on caveolae
Y Gambin, N Ariotti, KA McMahon, M Bastiani, E Sierecki, O Kovtun, ...
elife 3, e01434, 2014
Caveolae regulate the nanoscale organization of the plasma membrane to remotely control Ras signaling
N Ariotti, MA Fernández-Rojo, Y Zhou, MM Hill, TL Rodkey, KL Inder, ...
Journal of Cell Biology 204 (5), 777-792, 2014
Oncogenic K-Ras binds to an anionic membrane in two distinct orientations: a molecular dynamics analysis
P Prakash, Y Zhou, H Liang, JF Hancock, AA Gorfe
Biophysical journal 110 (5), 1125-1138, 2016
ω-3 polyunsaturated fatty acids direct differentiation of the membrane phenotype in mesenchymal stem cells to potentiate osteogenesis
KR Levental, MA Surma, AD Skinkle, JH Lorent, Y Zhou, C Klose, ...
Science advances 3 (11), eaao1193, 2017
Temporal production of the signaling lipid phosphatidic acid by phospholipase D2 determines the output of extracellular signal-regulated kinase signaling in cancer cells
F Zhang, Z Wang, M Lu, Y Yonekubo, X Liang, Y Zhang, P Wu, Y Zhou, ...
Molecular and cellular biology 34 (1), 84-95, 2014
Inhibition of acid sphingomyelinase depletes cellular phosphatidylserine and mislocalizes K-Ras from the plasma membrane
K Cho, D van der Hoeven, Y Zhou, M Maekawa, X Ma, W Chen, GD Fairn, ...
Molecular and cellular biology 36 (2), 363-374, 2016
Bile acids modulate signaling by functional perturbation of plasma membrane domains
Y Zhou, KN Maxwell, E Sezgin, M Lu, H Liang, JF Hancock, EJ Dial, ...
Journal of Biological Chemistry 288 (50), 35660-35670, 2013
Effect of salicylate on the elasticity, bending stiffness, and strength of SOPC membranes
Y Zhou, RM Raphael
Biophysical journal 89 (3), 1789-1801, 2005
Distinct binding preferences between Ras and Raf family members and the impact on oncogenic Ras signaling
EM Terrell, DE Durrant, DA Ritt, NE Sealover, E Sheffels, ...
Molecular cell 76 (6), 872-884. e5, 2019
Effect of indomethacin on bile acid-phospholipid interactions: implication for small intestinal injury induced by nonsteroidal anti-inflammatory drugs
Y Zhou, EJ Dial, R Doyen, LM Lichtenberger
American Journal of Physiology-Gastrointestinal and Liver Physiology 298 (5 …, 2010
HRAS‐driven cancer cells are vulnerable to TRPML1 inhibition
J Jung, KJ Cho, AK Naji, KN Clemons, CO Wong, M Villanueva, ...
EMBO reports 20 (4), e46685, 2019
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