Computational design of proteins targeting the conserved stem region of influenza hemagglutinin SJ Fleishman, TA Whitehead, DC Ekiert, C Dreyfus, JE Corn, EM Strauch, ... Science 332 (6031), 816-821, 2011 | 714 | 2011 |
De novo design of picomolar SARS-CoV-2 miniprotein inhibitors L Cao, I Goreshnik, B Coventry, JB Case, L Miller, L Kozodoy, RE Chen, ... Science 370 (6515), 426-431, 2020 | 657 | 2020 |
RosettaScripts: a scripting language interface to the Rosetta macromolecular modeling suite SJ Fleishman, A Leaver-Fay, JE Corn, EM Strauch, SD Khare, N Koga, ... PloS one 6 (6), e20161, 2011 | 643 | 2011 |
Design of protein-binding proteins from the target structure alone L Cao, B Coventry, I Goreshnik, B Huang, W Sheffler, JS Park, KM Jude, ... Nature 605 (7910), 551-560, 2022 | 338 | 2022 |
Community-wide assessment of protein-interface modeling suggests improvements to design methodology SJ Fleishman, TA Whitehead, EM Strauch, JE Corn, S Qin, HX Zhou, ... Journal of molecular biology 414 (2), 289-302, 2011 | 159 | 2011 |
Computational design of trimeric influenza-neutralizing proteins targeting the hemagglutinin receptor binding site EM Strauch, SM Bernard, D La, AJ Bohn, PS Lee, CE Anderson, ... Nature biotechnology 35 (7), 667-671, 2017 | 137 | 2017 |
Computational design of a pH-sensitive IgG binding protein EM Strauch, SJ Fleishman, D Baker Proceedings of the National Academy of Sciences 111 (2), 675-680, 2014 | 109 | 2014 |
Efficient production of membrane‐integrated and detergent‐soluble G protein‐coupled receptors in Escherichia coli AJ Link, G Skretas, EM Strauch, NS Chari, G Georgiou Protein Science 17 (10), 1857-1863, 2008 | 90 | 2008 |
Hotspot-Centric De Novo Design of Protein Binders SJ Fleishman, JE Corn, EM Strauch, TA Whitehead, J Karanicolas, ... Journal of molecular biology 413 (5), 1047-1062, 2011 | 65 | 2011 |
Escherichia coli tatC Mutations that Suppress Defective Twin-Arginine Transporter Signal Peptides EM Strauch, G Georgiou Journal of molecular biology 374 (2), 283-291, 2007 | 65 | 2007 |
Multiplex pairwise assembly of array-derived DNA oligonucleotides JC Klein, MJ Lajoie, JJ Schwartz, EM Strauch, J Nelson, D Baker, ... Nucleic acids research 44 (5), e43-e43, 2016 | 62 | 2016 |
A bacterial two‐hybrid system based on the twin‐arginine transporter pathway of E. coli EM Strauch, G Georgiou Protein science 16 (5), 1001-1008, 2007 | 35 | 2007 |
Large-scale design and refinement of stable proteins using sequence-only models JM Singer, S Novotney, D Strickland, HK Haddox, N Leiby, GJ Rocklin, ... PloS one 17 (3), e0265020, 2022 | 30 | 2022 |
Rosetta in CAPRI rounds 13–19 SJ Fleishman, JE Corn, EM Strauch, TA Whitehead, I Andre, J Thompson, ... Proteins: Structure, Function, and Bioinformatics 78 (15), 3212-3218, 2010 | 23 | 2010 |
Rapid diagnostic assay for intact influenza virus using a high affinity hemagglutinin binding protein CE Anderson, CA Holstein, EM Strauch, S Bennett, A Chevalier, J Nelson, ... Analytical chemistry 89 (12), 6608-6615, 2017 | 21 | 2017 |
Deep learning of protein sequence design of protein–protein interactions R Syrlybaeva, EM Strauch Bioinformatics 39 (1), btac733, 2023 | 18 | 2023 |
An integrated device for the rapid and sensitive detection of the influenza hemagglutinin CE Anderson, JR Buser, AM Fleming, EM Strauch, PD Ladd, J Englund, ... Lab on a Chip 19 (5), 885-896, 2019 | 16 | 2019 |
Sampling of structure and sequence space of small protein folds TW Linsky, K Noble, AR Tobin, R Crow, L Carter, JL Urbauer, D Baker, ... Nature communications 13 (1), 7151, 2022 | 15 | 2022 |
Robust de novo design of protein binding proteins from target structural information alone L Cao, B Coventry, I Goreshnik, B Huang, JS Park, KM Jude, I Marković, ... BioRxiv, 2021.09. 04.459002, 2021 | 15 | 2021 |
Skp1 dimerization conceals its F-box protein binding site HW Kim, A Eletsky, KJ Gonzalez, H Van Der Wel, EM Strauch, ... Biochemistry 59 (15), 1527-1536, 2020 | 15 | 2020 |