| NLRP3 inflammasome activation drives tau pathology C Ising, C Venegas, S Zhang, H Scheiblich, SV Schmidt, A Vieira-Saecker, ... Nature 575 (7784), 669-673, 2019 | 935 | 2019 |
| Inflammasome signalling in brain function and neurodegenerative disease MT Heneka, RM McManus, E Latz Nature Reviews Neuroscience 19 (10), 610-621, 2018 | 606 | 2018 |
| IFN-γ production by amyloid β–specific Th1 cells promotes microglial activation and increases plaque burden in a mouse model of Alzheimer’s disease TC Browne, K McQuillan, RM McManus, JA O’Reilly, KHG Mills, MA Lynch The Journal of Immunology 190 (5), 2241-2251, 2013 | 295 | 2013 |
| Role of neuroinflammation in neurodegeneration: new insights RM McManus, MT Heneka Alzheimer's research & therapy 9, 1-7, 2017 | 256 | 2017 |
| Targeting neuroinflammation to treat Alzheimer’s disease A Ardura-Fabregat, E Boddeke, A Boza-Serrano, S Brioschi, ... CNS drugs 31, 1057-1082, 2017 | 237 | 2017 |
| Lung CD4 tissue-resident memory T cells mediate adaptive immunity induced by previous infection of mice with Bordetella pertussis MM Wilk, A Misiak, RM McManus, AC Allen, MA Lynch, KHG Mills The Journal of Immunology 199 (1), 233-243, 2017 | 154 | 2017 |
| Respiratory infection promotes T cell infiltration and amyloid-β deposition in APP/PS1 mice RM McManus, SC Higgins, KHG Mills, MA Lynch Neurobiology of aging 35 (1), 109-121, 2014 | 130 | 2014 |
| Soluble Aβ oligomers and protofibrils induce NLRP3 inflammasome activation in microglia A Lučiūnaitė, RM McManus, M Jankunec, I Rácz, C Dansokho, ... Journal of neurochemistry 155 (6), 650-661, 2020 | 125 | 2020 |
| How location and cellular signaling combine to activate the NLRP3 inflammasome A Akbal, A Dernst, M Lovotti, MSJ Mangan, RM McManus, E Latz Cellular & molecular immunology 19 (11), 1201-1214, 2022 | 62 | 2022 |
| T cells—protective or pathogenic in Alzheimer’s disease? RM McManus, KHG Mills, MA Lynch Journal of Neuroimmune Pharmacology 10, 547-560, 2015 | 43 | 2015 |
| Soluble TAM receptors sAXL and sTyro3 predict structural and functional protection in Alzheimer’s disease F Brosseron, A Maass, L Kleineidam, KA Ravichandran, PG González, ... Neuron 110 (6), 1009-1022. e4, 2022 | 30 | 2022 |
| FTY720 attenuates infection-induced enhancement of Aβ accumulation in APP/PS1 mice by modulating astrocytic activation RM McManus, OM Finucane, MM Wilk, KHG Mills, MA Lynch Journal of Neuroimmune Pharmacology 12, 670-681, 2017 | 30 | 2017 |
| The age-related neuroinflammatory environment promotes macrophage activation, which negatively impacts synaptic function DA Costello, K Keenan, RM McManus, A Falvey, MA Lynch Neurobiology of aging 43, 140-148, 2016 | 26 | 2016 |
| Serum IL-6, sAXL, and YKL-40 as systemic correlates of reduced brain structure and function in Alzheimer’s disease: results from the DELCODE study F Brosseron, A Maass, L Kleineidam, KA Ravichandran, CC Kolbe, ... Alzheimer's research & therapy 15 (1), 13, 2023 | 15 | 2023 |
| T cells in Alzheimer's disease: space invaders RM McManus, MT Heneka The Lancet Neurology 19 (4), 285-287, 2020 | 12 | 2020 |
| p38 inhibition decreases Tau toxicity in microglia and improves their phagocytic function JR Perea, M Bolós, R Cuadros, E García, V García-Escudero, ... Molecular neurobiology 59 (3), 1632-1648, 2022 | 11 | 2022 |
| Author correction: inflammasome signalling in brain function and neurodegenerative disease MT Heneka, RM McManus, E Latz Nature Reviews Neuroscience 20 (3), 187-187, 2019 | 11 | 2019 |
| The role of immunity in Alzheimer's disease RM McManus Advanced Biology 6 (5), 2101166, 2022 | 10 | 2022 |
| NLRP3‐directed antisense oligonucleotides reduce microglial immunoactivities in vitro C Braatz, MP Komes, KA Ravichandran, MG de Fragas, A Griep, ... Journal of Neurochemistry, 2023 | 5 | 2023 |
| NLRP3-mediated glutaminolysis regulates microglia in Alzheimer's disease R McManus, MP Komes, A Griep, F Santarelli, S Schwartz, JR Perea, ... | 3 | 2022 |
