| DNA methylation dynamics during B cell maturation underlie a continuum of disease phenotypes in chronic lymphocytic leukemia CC Oakes, M Seifert, Y Assenov, L Gu, M Przekopowitz, AS Ruppert, ... Nature genetics 48 (3), 253-264, 2016 | 331 | 2016 |
| Long noncoding RNA TARID directs demethylation and activation of the tumor suppressor TCF21 via GADD45A K Arab, YJ Park, AM Lindroth, A Schäfer, C Oakes, D Weichenhan, ... Molecular cell 55 (4), 604-614, 2014 | 313 | 2014 |
| DNMT and HDAC inhibitors induce cryptic transcription start sites encoded in long terminal repeats D Brocks, CR Schmidt, M Daskalakis, HS Jang, NM Shah, D Li, J Li, ... Nature genetics 49 (7), 1052-1060, 2017 | 293 | 2017 |
| Developmental acquisition of genome-wide DNA methylation occurs prior to meiosis in male germ cells CC Oakes, S La Salle, DJ Smiraglia, B Robaire, JM Trasler Developmental biology 307 (2), 368-379, 2007 | 281 | 2007 |
| Intratumor DNA methylation heterogeneity reflects clonal evolution in aggressive prostate cancer D Brocks, Y Assenov, S Minner, O Bogatyrova, R Simon, C Koop, ... Cell reports 8 (3), 798-806, 2014 | 273 | 2014 |
| Aging results in hypermethylation of ribosomal DNA in sperm and liver of male rats CC Oakes, DJ Smiraglia, C Plass, JM Trasler, B Robaire Proceedings of the National Academy of Sciences 100 (4), 1775-1780, 2003 | 238 | 2003 |
| p53-dependent non-coding RNA networks in chronic lymphocytic leukemia CJ Blume, A Hotz-Wagenblatt, J Hüllein, L Sellner, A Jethwa, T Stolz, ... Leukemia 29 (10), 2015 | 189 | 2015 |
| A unique configuration of genome-wide DNA methylation patterns in the testis CC Oakes, S La Salle, DJ Smiraglia, B Robaire, JM Trasler Proceedings of the National Academy of Sciences 104 (1), 228-233, 2007 | 181 | 2007 |
| Epigenetic Upregulation of lncRNAs at 13q14.3 in Leukemia Is Linked to the In Cis Downregulation of a Gene Cluster That Targets NF-kB A Garding, N Bhattacharya, R Claus, M Ruppel, C Tschuch, K Filarsky, ... PLoS genetics 9 (4), e1003373, 2013 | 178 | 2013 |
| Evolution of DNA methylation is linked to genetic aberrations in chronic lymphocytic leukemia CC Oakes, R Claus, L Gu, Y Assenov, J Hüllein, M Zucknick, M Bieg, ... Cancer discovery 4 (3), 348-361, 2014 | 164 | 2014 |
| Drug-perturbation-based stratification of blood cancer S Dietrich, M Oleś, J Lu, L Sellner, S Anders, B Velten, B Wu, J Huellein, ... The Journal of clinical investigation 128 (1), 427-445, 2018 | 156 | 2018 |
| BAZ2A (TIP5) is involved in epigenetic alterations in prostate cancer and its overexpression predicts disease recurrence L Gu, SC Frommel, CC Oakes, R Simon, K Grupp, CY Gerig, D Bär, ... Nature genetics 47 (1), 22-30, 2015 | 147 | 2015 |
| Quantitative DNA methylation analysis identifies a single CpG dinucleotide important for ZAP-70 expression and predictive of prognosis in chronic lymphocytic leukemia R Claus, DM Lucas, S Stilgenbauer, AS Ruppert, L Yu, M Zucknick, ... Journal of Clinical Oncology 30 (20), 2483-2491, 2012 | 146 | 2012 |
| Loss of spermatogonia and wide-spread DNA methylation defects in newborn male mice deficient in DNMT3L S La Salle, CC Oakes, OR Neaga, D Bourc'his, TH Bestor, JM Trasler BMC developmental biology 7, 1-18, 2007 | 120 | 2007 |
| Evaluation of a quantitative DNA methylation analysis technique using methylation-sensitive/dependent restriction enzymes and real-time PCR CC Oakes, S La Salle, B Robaire, JM Trasler Epigenetics 1 (3), 146-152, 2006 | 119 | 2006 |
| High-content screening identifies kinase inhibitors that overcome venetoclax resistance in activated CLL cells S Oppermann, J Ylanko, Y Shi, S Hariharan, CC Oakes, PM Brauer, ... Blood, The Journal of the American Society of Hematology 128 (7), 934-947, 2016 | 118 | 2016 |
| Epigenetics in acute myeloid leukemia C Plass, C Oakes, W Blum, G Marcucci Seminars in oncology 35 (4), 378-387, 2008 | 117 | 2008 |
| Genomic analysis of hairy cell leukemia identifies novel recurrent genetic alterations BH Durham, B Getta, S Dietrich, J Taylor, H Won, JM Bogenberger, ... Blood, The Journal of the American Society of Hematology 130 (14), 1644-1648, 2017 | 114 | 2017 |
| Validation of ZAP-70 methylation and its relative significance in predicting outcome in chronic lymphocytic leukemia R Claus, DM Lucas, AS Ruppert, KE Williams, D Weng, K Patterson, ... Blood, The Journal of the American Society of Hematology 124 (1), 42-48, 2014 | 93 | 2014 |
| Adverse effects of 5-aza-2′-deoxycytidine on spermatogenesis include reduced sperm function and selective inhibition of de novo DNA methylation CC Oakes, TLJ Kelly, B Robaire, JM Trasler Journal of Pharmacology and Experimental Therapeutics 322 (3), 1171-1180, 2007 | 90 | 2007 |
