| An antibody exo Diels-Alderase inhibitor complex at 1.95 angstrom resolution A Heine, EA Stura, JT Yli-Kauhaluoma, C Gao, Q Deng, BR Beno, ... Science 279 (5358), 1934-1940, 1998 | 179 | 1998 |
| Evolution of shape complementarity and catalytic efficiency from a primordial antibody template J Xu, Q Deng, J Chen, KN Houk, J Bartek, D Hilvert, IA Wilson Science 286 (5448), 2345-2348, 1999 | 154 | 1999 |
| A single point mutation in ecdysone receptor leads to increased ligand specificity: Implication for gene switch applications MB Kumar, T Fujimoto, DW Potter, Q Deng, SR Palli Proceedings of the National Academy of Sciences 99 (23), 14710-14715, 2002 | 118 | 2002 |
| Benzannulation reactions of Fischer carbene complexes for the synthesis of indolocarbazoles CA Merlic, Y You, DM McInnes, AL Zechman, MM Miller, Q Deng Tetrahedron 57 (24), 5199-5212, 2001 | 101 | 2001 |
| Discovery of novel tricyclic full agonists for the G-protein-coupled niacin receptor 109A with minimized flushing in rats HC Shen, FX Ding, Q Deng, LC Wilsie, ML Krsmanovic, AK Taggart, ... Journal of medicinal chemistry 52 (8), 2587-2602, 2009 | 77 | 2009 |
| CETP inhibitors A Ali, JM Napolitano, Q Deng, Z Lu, PJ Sinclair, GE Taylor, CF Thompson, ... US Patent 7,652,049, 2010 | 71 | 2010 |
| CETP inhibitors A Ali, JM Napolitano, Q Deng, Z Lu, PJ Sinclair, GE Taylor, CF Thompson, ... US Patent 7,652,049, 2010 | 69 | 2010 |
| Shape Complementarity, Binding‐Site Dynamics, and Transition State Stabilization: A Theoretical Study of Diels–Alder Catalysis by Antibody 1E9 J Chen, Q Deng, R Wang, KN Houk, D Hilvert ChemBioChem 1 (4), 255-261, 2000 | 68 | 2000 |
| CETP inhibitors A Ali, JM Napolitano, Q Deng, Z Lu, PJ Sinclair, GE Taylor, CF Thompson, ... US Patent 7,652,049, 2010 | 66 | 2010 |
| CETP inhibitors A Ali, JM Napolitano, Q Deng, Z Lu, PJ Sinclair, GE Taylor, CF Thompson, ... US Patent 7,652,049, 2010 | 66 | 2010 |
| CETP inhibitors A Ali, JM Napolitano, Q Deng, Z Lu, PJ Sinclair, GE Taylor, CF Thompson, ... US Patent 7,652,049, 2010 | 66 | 2010 |
| 1-benzyl-4-[4'-fluoro-5'-isopropyl-2'-methoxy-4-(trifluoromethyl) biphenyl-2-yl] imidazolidin-2-one; cholesteryl ester transfer protein inhibitor; raising HDL-cholesterol … A Ali, JM Napolitano, Q Deng, Z Lu, PJ Sinclair, GE Taylor, CF Thompson, ... US Patent 7,652,049, 2010 | 66* | 2010 |
| Novel 3, 4-dihydroquinolin-2 (1H)-one inhibitors of human glycogen phosphorylase a KG Rosauer, AK Ogawa, CA Willoughby, KP Ellsworth, WM Geissler, ... Bioorganic & Medicinal Chemistry Letters 13 (24), 4385-4388, 2003 | 59 | 2003 |
| A strategy of employing aminoheterocycles as amide mimics to identify novel, potent and bioavailable soluble epoxide hydrolase inhibitors HC Shen, FX Ding, Q Deng, S Xu, X Tong, X Zhang, Y Chen, G Zhou, ... Bioorganic & medicinal chemistry letters 19 (19), 5716-5721, 2009 | 57 | 2009 |
| Transition structures of the ene reactions of cyclopropene Q Deng, BE Thomas, KN Houk, P Dowd Journal of the American Chemical Society 119 (29), 6902-6908, 1997 | 57 | 1997 |
| Discovery of a biaryl cyclohexene carboxylic acid (MK-6892): a potent and selective high affinity niacin receptor full agonist with reduced flushing profiles in animals as a … HC Shen, FX Ding, S Raghavan, Q Deng, S Luell, MJ Forrest, ... Journal of medicinal chemistry 53 (6), 2666-2670, 2010 | 54 | 2010 |
| Identification of Leu276 of the S1P1 receptor and Phe263 of the S1P3 receptor in interaction with receptor specific agonists by molecular modeling, site-directed mutagenesis … Q Deng, JA Clemas, G Chrebet, P Fischer, JJ Hale, Z Li, SG Mills, ... Molecular pharmacology 71 (3), 724-735, 2007 | 53 | 2007 |
| Discovery of biaryl anthranilides as full agonists for the high affinity niacin receptor HC Shen, FX Ding, S Luell, MJ Forrest, E Carballo-Jane, KK Wu, TJ Wu, ... Journal of medicinal chemistry 50 (25), 6303-6306, 2007 | 51 | 2007 |
| A new class of glycogen phosphorylase inhibitors Z Lu, J Bohn, R Bergeron, Q Deng, KP Ellsworth, WM Geissler, G Harris, ... Bioorganic & medicinal chemistry letters 13 (22), 4125-4128, 2003 | 51 | 2003 |
| Discovery of a highly potent, selective, and bioavailable soluble epoxide hydrolase inhibitor with excellent ex vivo target engagement HC Shen, FX Ding, S Wang, Q Deng, X Zhang, Y Chen, G Zhou, S Xu, ... Journal of medicinal chemistry 52 (16), 5009-5012, 2009 | 49 | 2009 |
