Nanomaterial-based blood-brain-barrier (BBB) crossing strategies J Xie, Z Shen, Y Anraku, K Kataoka, X Chen Biomaterials 224, 119491, 2019 | 359 | 2019 |
Therapeutic polymersome nanoreactors with tumor-specific activable cascade reactions for cooperative cancer therapy W Ke, J Li, F Mohammed, Y Wang, K Tou, X Liu, P Wen, H Kinoh, ... Acs Nano 13 (2), 2357-2369, 2019 | 248 | 2019 |
Spontaneous formation of nanosized unilamellar polyion complex vesicles with tunable size and properties Y Anraku, A Kishimura, M Oba, Y Yamasaki, K Kataoka Journal of the American Chemical Society 132 (5), 1631-1636, 2010 | 243 | 2010 |
Glycaemic control boosts glucosylated nanocarrier crossing the BBB into the brain Y Anraku, H Kuwahara, Y Fukusato, A Mizoguchi, T Ishii, K Nitta, ... Nature communications 8 (1), 1001, 2017 | 235 | 2017 |
Therapeutic vesicular nanoreactors with tumor‐specific activation and self‐destruction for synergistic tumor ablation J Li, A Dirisala, Z Ge, Y Wang, W Yin, W Ke, K Toh, J Xie, Y Matsumoto, ... Angewandte Chemie 129 (45), 14213-14218, 2017 | 206 | 2017 |
Systemically injectable enzyme‐loaded polyion complex vesicles as in vivo nanoreactors functioning in tumors Y Anraku, A Kishimura, M Kamiya, S Tanaka, T Nomoto, K Toh, ... Angewandte Chemie International Edition 55 (2), 560-565, 2016 | 182 | 2016 |
Polyion complex vesicles for photoinduced intracellular delivery of amphiphilic photosensitizer H Chen, L Xiao, Y Anraku, P Mi, X Liu, H Cabral, A Inoue, T Nomoto, ... Journal of the American Chemical Society 136 (1), 157-163, 2014 | 177 | 2014 |
Monodispersed polymeric nanocapsules: spontaneous evolution and morphology transition from reducible hetero-PEG PICmicelles by controlled degradation WF Dong, A Kishimura, Y Anraku, S Chuanoi, K Kataoka Journal of the American Chemical Society 131 (11), 3804-3805, 2009 | 171 | 2009 |
Blood-brain barrier–penetrating siRNA nanomedicine for Alzheimer’s disease therapy Y Zhou, F Zhu, Y Liu, M Zheng, Y Wang, D Zhang, Y Anraku, Y Zou, J Li, ... Science advances 6 (41), eabc7031, 2020 | 154 | 2020 |
Systemic brain delivery of antisense oligonucleotides across the blood–brain barrier with a glucose‐coated polymeric nanocarrier HS Min, HJ Kim, M Naito, S Ogura, K Toh, K Hayashi, BS Kim, ... Angewandte Chemie International Edition 59 (21), 8173-8180, 2020 | 139 | 2020 |
Size-controlled long-circulating PICsome as a ruler to measure critical cut-off disposition size into normal and tumor tissues Y Anraku, A Kishimura, A Kobayashi, M Oba, K Kataoka Chemical communications 47 (21), 6054-6056, 2011 | 119 | 2011 |
Smart multilayered assembly for biocompatible siRNA delivery featuring dissolvable silica, endosome-disrupting polycation, and detachable PEG T Suma, K Miyata, Y Anraku, S Watanabe, RJ Christie, H Takemoto, ... ACS nano 6 (8), 6693-6705, 2012 | 110 | 2012 |
Self‐boosting catalytic nanoreactors integrated with triggerable crosslinking membrane networks for initiation of immunogenic cell death by pyroptosis J Li, Y Anraku, K Kataoka Angewandte Chemie 132 (32), 13628-13632, 2020 | 101 | 2020 |
Targeting nanoparticles to the brain by exploiting the blood–brain barrier impermeability to selectively label the brain endothelium D Gonzalez-Carter, X Liu, TA Tockary, A Dirisala, K Toh, Y Anraku, ... Proceedings of the National Academy of Sciences 117 (32), 19141-19150, 2020 | 93 | 2020 |
Functionalization of single-walled carbon nanotube by the covalent modification with polymer chains H Kitano, K Tachimoto, Y Anraku Journal of colloid and interface science 306 (1), 28-33, 2007 | 90 | 2007 |
Bioactive polymeric metallosomes self-assembled through block copolymer–metal complexation K Osada, H Cabral, Y Mochida, S Lee, K Nagata, T Matsuura, ... Journal of the American Chemical Society 134 (32), 13172-13175, 2012 | 83 | 2012 |
Fabrication of polyion complex vesicles with enhanced salt and temperature resistance and their potential applications as enzymatic nanoreactors S Chuanoi, Y Anraku, M Hori, A Kishimura, K Kataoka Biomacromolecules 15 (7), 2389-2397, 2014 | 82 | 2014 |
Living unimodal growth of polyion complex vesicles via two-dimensional supramolecular polymerization Y Anraku, A Kishimura, Y Yamasaki, K Kataoka Journal of the American Chemical Society 135 (4), 1423-1429, 2013 | 79 | 2013 |
SPIO-PICsome: development of a highly sensitive and stealth-capable MRI nano-agent for tumor detection using SPIO-loaded unilamellar polyion complex vesicles (PICsomes) D Kokuryo, Y Anraku, A Kishimura, S Tanaka, MR Kano, J Kershaw, ... Journal of controlled release 169 (3), 220-227, 2013 | 72 | 2013 |
Enzyme-loaded polyion complex vesicles as in vivo nanoreactors working sustainably under the blood circulation: characterization and functional evaluation D Sueyoshi, Y Anraku, T Komatsu, Y Urano, K Kataoka Biomacromolecules 18 (4), 1189-1196, 2017 | 68 | 2017 |