Martijn J. Wilmer
Martijn J. Wilmer
Radboud University Nijmegen Medical Centre
Patvirtintas el. paštas
Kidney-on-a-chip technology for drug-induced nephrotoxicity screening
MJ Wilmer, CP Ng, HL Lanz, P Vulto, L Suter-Dick, R Masereeuw
Trends in biotechnology 34 (2), 156-170, 2016
Novel conditionally immortalized human proximal tubule cell line expressing functional influx and efflux transporters
MJ Wilmer, MA Saleem, R Masereeuw, L Ni, TJ van der Velden, ...
Cell and tissue research 339, 449-457, 2010
Cystinosis: practical tools for diagnosis and treatment
MJ Wilmer, JP Schoeber, LP van den Heuvel, EN Levtchenko
Pediatric nephrology 26, 205-215, 2011
Bioengineered kidney tubules efficiently excrete uremic toxins
J Jansen, M Fedecostante, MJ Wilmer, JG Peters, UM Kreuser, ...
Scientific reports 6 (1), 26715, 2016
Uremic toxins inhibit renal metabolic capacity through interference with glucuronidation and mitochondrial respiration
HAM Mutsaers, MJG Wilmer, D Reijnders, J Jansen, PHH van den Broek, ...
Biochimica et Biophysica Acta (BBA)-Molecular Basis of Disease 1832 (1), 142-150, 2013
A human renal proximal tubule cell line with stable organic anion transporter 1 and 3 expression predictive for antiviral-induced toxicity
TTG Nieskens, JGP Peters, MJ Schreurs, N Smits, R Woestenenk, ...
The AAPS journal 18, 465-475, 2016
Cysteamine restores glutathione redox status in cultured cystinotic proximal tubular epithelial cells
MJ Wilmer, LAJ Kluijtmans, TJ van Der Velden, PH Willems, PG Scheffer, ...
Biochimica et Biophysica Acta (BBA)-Molecular Basis of Disease 1812 (6), 643-651, 2011
Human proximal tubule epithelial cells cultured on hollow fibers: living membranes that actively transport organic cations
J Jansen, IE De Napoli, M Fedecostante, CMS Schophuizen, ...
Scientific reports 5 (1), 16702, 2015
Nephrotoxicity and kidney transport assessment on 3D perfused proximal tubules
MK Vormann, L Gijzen, S Hutter, L Boot, A Nicolas, A van den Heuvel, ...
The AAPS journal 20, 1-11, 2018
A morphological and functional comparison of proximal tubule cell lines established from human urine and kidney tissue
J Jansen, CMS Schophuizen, MJ Wilmer, SHM Lahham, HAM Mutsaers, ...
Experimental cell research 323 (1), 87-99, 2014
The pathogenesis of cystinosis: mechanisms beyond cystine accumulation
MJ Wilmer, F Emma, EN Levtchenko
American Journal of Physiology-Renal Physiology 299 (5), F905-F916, 2010
Receptor-mediated endocytosis and endosomal acidification is impaired in proximal tubule epithelial cells of Dent disease patients
CM Gorvin, MJ Wilmer, SE Piret, B Harding, LP Van Den Heuvel, O Wrong, ...
Proceedings of the National Academy of Sciences 110 (17), 7014-7019, 2013
Strict cysteamine dose regimen is required to prevent nocturnal cystine accumulation in cystinosis
EN Levtchenko, CM van Dael, AC de Graaf-Hess, MJG Wilmer, ...
Pediatric nephrology 21, 110-113, 2006
Elevated oxidized glutathione in cystinotic proximal tubular epithelial cells
MJG Wilmer, A de Graaf-Hess, HJ Blom, HBPM Dijkman, LA Monnens, ...
Biochemical and biophysical research communications 337 (2), 610-614, 2005
Screening of drug-transporter interactions in a 3D microfluidic renal proximal tubule on a chip
J Vriend, TTG Nieskens, MK Vormann, BT van den Berge, ...
The AAPS journal 20, 1-13, 2018
Kidney-on-a-chip technology for renal proximal tubule tissue reconstruction
TTG Nieskens, MJ Wilmer
European journal of pharmacology 790, 46-56, 2016
Alkaline phosphatase protects against renal inflammation through dephosphorylation of lipopolysaccharide and adenosine triphosphate
E Peters, S Geraci, S Heemskerk, MJ Wilmer, A Bilos, B Kraenzlin, ...
British journal of pharmacology 172 (20), 4932-4945, 2015
Altered status of glutathione and its metabolites in cystinotic cells
E Levtchenko, A de Graaf-Hess, M Wilmer, L van den Heuvel, L Monnens, ...
Nephrology Dialysis Transplantation 20 (9), 1828-1832, 2005
Epithelial-to-mesenchymal transition in fibrosis: collagen type I expression is highly upregulated after EMT, but does not contribute to collagen deposition
NA Hosper, PP van den Berg, S de Rond, ER Popa, MJ Wilmer, ...
Experimental cell research 319 (19), 3000-3009, 2013
Mesenchymal stem cell-conditioned medium accelerates regeneration of human renal proximal tubule epithelial cells after gentamicin toxicity
R Moghadasali, HAM Mutsaers, M Azarnia, N Aghdami, H Baharvand, ...
Experimental and Toxicologic Pathology 65 (5), 595-600, 2013
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Straipsniai 1–20