| Kidney-on-a-chip technology for drug-induced nephrotoxicity screening MJ Wilmer, CP Ng, HL Lanz, P Vulto, L Suter-Dick, R Masereeuw Trends in biotechnology 34 (2), 156-170, 2016 | 407 | 2016 |
| Novel conditionally immortalized human proximal tubule cell line expressing functional influx and efflux transporters MJ Wilmer, MA Saleem, R Masereeuw, L Ni, TJ Van Der Velden, ... Cell and tissue research 339, 449-457, 2010 | 252 | 2010 |
| Cystinosis: practical tools for diagnosis and treatment MJ Wilmer, JP Schoeber, LP Van Den Heuvel, EN Levtchenko Pediatric nephrology 26, 205-215, 2011 | 155 | 2011 |
| Bioengineered kidney tubules efficiently excrete uremic toxins J Jansen, M Fedecostante, MJ Wilmer, JG Peters, UM Kreuser, ... Scientific reports 6 (1), 26715, 2016 | 150 | 2016 |
| Uremic toxins inhibit renal metabolic capacity through interference with glucuronidation and mitochondrial respiration HAM Mutsaers, MJG Wilmer, D Reijnders, J Jansen, PHH van den Broek, ... Biochimica et Biophysica Acta (BBA)-Molecular Basis of Disease 1832 (1), 142-150, 2013 | 132 | 2013 |
| A human renal proximal tubule cell line with stable organic anion transporter 1 and 3 expression predictive for antiviral-induced toxicity TTG Nieskens, JGP Peters, MJ Schreurs, N Smits, R Woestenenk, ... The AAPS journal 18, 465-475, 2016 | 130 | 2016 |
| Nephrotoxicity and kidney transport assessment on 3D perfused proximal tubules MK Vormann, L Gijzen, S Hutter, L Boot, A Nicolas, A van den Heuvel, ... The AAPS journal 20, 1-11, 2018 | 127 | 2018 |
| Human proximal tubule epithelial cells cultured on hollow fibers: living membranes that actively transport organic cations J Jansen, IE De Napoli, M Fedecostante, CMS Schophuizen, ... Scientific reports 5 (1), 16702, 2015 | 120 | 2015 |
| A morphological and functional comparison of proximal tubule cell lines established from human urine and kidney tissue J Jansen, CMS Schophuizen, MJ Wilmer, SHM Lahham, HAM Mutsaers, ... Experimental cell research 323 (1), 87-99, 2014 | 120 | 2014 |
| Cysteamine restores glutathione redox status in cultured cystinotic proximal tubular epithelial cells MJ Wilmer, LAJ Kluijtmans, TJ van Der Velden, PH Willems, PG Scheffer, ... Biochimica et Biophysica Acta (BBA)-Molecular Basis of Disease 1812 (6), 643-651, 2011 | 120 | 2011 |
| The pathogenesis of cystinosis: mechanisms beyond cystine accumulation MJ Wilmer, F Emma, EN Levtchenko American Journal of Physiology-Renal Physiology 299 (5), F905-F916, 2010 | 111 | 2010 |
| Receptor-mediated endocytosis and endosomal acidification is impaired in proximal tubule epithelial cells of Dent disease patients CM Gorvin, MJ Wilmer, SE Piret, B Harding, LP Van Den Heuvel, O Wrong, ... Proceedings of the National Academy of Sciences 110 (17), 7014-7019, 2013 | 98 | 2013 |
| Kidney-on-a-chip technology for renal proximal tubule tissue reconstruction TTG Nieskens, MJ Wilmer European journal of pharmacology 790, 46-56, 2016 | 90 | 2016 |
| Strict cysteamine dose regimen is required to prevent nocturnal cystine accumulation in cystinosis EN Levtchenko, CM van Dael, AC de Graaf-Hess, MJG Wilmer, ... Pediatric nephrology 21, 110-113, 2006 | 89 | 2006 |
| Screening of drug-transporter interactions in a 3D microfluidic renal proximal tubule on a chip J Vriend, TTG Nieskens, MK Vormann, BT van den Berge, ... The AAPS journal 20, 1-13, 2018 | 87 | 2018 |
| Alkaline phosphatase protects against renal inflammation through dephosphorylation of lipopolysaccharide and adenosine triphosphate E Peters, S Geraci, S Heemskerk, MJ Wilmer, A Bilos, B Kraenzlin, ... British journal of pharmacology 172 (20), 4932-4945, 2015 | 86 | 2015 |
| Elevated oxidized glutathione in cystinotic proximal tubular epithelial cells MJG Wilmer, A de Graaf-Hess, HJ Blom, HBPM Dijkman, LA Monnens, ... Biochemical and biophysical research communications 337 (2), 610-614, 2005 | 85 | 2005 |
| Flow stimulates drug transport in a human kidney proximal tubule-on-a-chip independent of primary cilia J Vriend, JGP Peters, TTG Nieskens, R Škovroňová, N Blaimschein, ... Biochimica et Biophysica Acta (BBA)-General Subjects 1864 (1), 129433, 2020 | 77 | 2020 |
| Epithelial-to-mesenchymal transition in fibrosis: collagen type I expression is highly upregulated after EMT, but does not contribute to collagen deposition NA Hosper, PP van den Berg, S de Rond, ER Popa, MJ Wilmer, ... Experimental cell research 319 (19), 3000-3009, 2013 | 76 | 2013 |
| Implementation of a human renal proximal tubule on a chip for nephrotoxicity and drug interaction studies MK Vormann, J Vriend, HL Lanz, L Gijzen, A van den Heuvel, S Hutter, ... Journal of Pharmaceutical Sciences 110 (4), 1601-1614, 2021 | 75 | 2021 |
