| A chemical probe selectively inhibits G9a and GLP methyltransferase activity in cells M Vedadi, D Barsyte-Lovejoy, F Liu, S Rival-Gervier, A Allali-Hassani, ... Nature chemical biology 7 (8), 566-574, 2011 | 547 | 2011 |
| 5-hmC in the brain is abundant in synaptic genes and shows differences at the exon-intron boundary T Khare, S Pai, K Koncevicius, M Pal, E Kriukiene, Z Liutkeviciute, M Irimia, ... Nature structural & molecular biology 19 (10), 1037-1043, 2012 | 281 | 2012 |
| The vermiform appendix impacts the risk of developing Parkinson’s disease BA Killinger, Z Madaj, JW Sikora, N Rey, AJ Haas, Y Vepa, D Lindqvist, ... Science translational medicine 10 (465), eaar5280, 2018 | 270 | 2018 |
| Triggers, facilitators, and aggravators: redefining Parkinson’s disease pathogenesis ME Johnson, B Stecher, V Labrie, L Brundin, P Brundin Trends in neurosciences 42 (1), 4-13, 2019 | 267 | 2019 |
| Serine racemase is associated with schizophrenia susceptibility in humans and in a mouse model V Labrie, R Fukumura, A Rastogi, LJ Fick, W Wang, PC Boutros, ... Human molecular genetics 18 (17), 3227-3243, 2009 | 204 | 2009 |
| D-serine augments NMDA-NR2B receptor-dependent hippocampal long-term depression and spatial reversal learning S Duffy, V Labrie, JC Roder Neuropsychopharmacology 33 (5), 1004-1018, 2008 | 204 | 2008 |
| Epigenetic dysregulation of enhancers in neurons is associated with Alzheimer’s disease pathology and cognitive symptoms P Li, L Marshall, G Oh, JL Jakubowski, D Groot, Y He, T Wang, A Petronis, ... Nature communications 10 (1), 2246, 2019 | 193 | 2019 |
| Modulators of the glycine site on NMDA receptors, d-serine and ALX 5407, display similar beneficial effects to clozapine in mouse models of schizophrenia T Lipina, V Labrie, I Weiner, J Roder Psychopharmacology 179, 54-67, 2005 | 183 | 2005 |
| The involvement of the NMDA receptor D-serine/glycine site in the pathophysiology and treatment of schizophrenia V Labrie, JC Roder Neuroscience & Biobehavioral Reviews 34 (3), 351-372, 2010 | 156 | 2010 |
| Mice with reduced NMDA receptor glycine affinity model some of the negative and cognitive symptoms of schizophrenia V Labrie, T Lipina, JC Roder Psychopharmacology 200, 217-230, 2008 | 154 | 2008 |
| Epigenetics of major psychosis: progress, problems and perspectives V Labrie, S Pai, A Petronis Trends in genetics 28 (9), 427-435, 2012 | 146 | 2012 |
| Contributions of the D-serine pathway to schizophrenia V Labrie, AHC Wong, JC Roder Neuropharmacology 62 (3), 1484-1503, 2012 | 118 | 2012 |
| Lactase nonpersistence is directed by DNA-variation-dependent epigenetic aging V Labrie, OJ Buske, E Oh, R Jeremian, C Ptak, G Gasiūnas, A Maleckas, ... Nature Structural & Molecular Biology 23 (6), 566-573, 2016 | 102 | 2016 |
| Genetic inactivation of D-amino acid oxidase enhances extinction and reversal learning in mice V Labrie, S Duffy, W Wang, SW Barger, GB Baker, JC Roder Learning & memory 16 (1), 28-37, 2009 | 94 | 2009 |
| Parkinson’s disease-linked D620N VPS35 knockin mice manifest tau neuropathology and dopaminergic neurodegeneration X Chen, JK Kordich, ET Williams, N Levine, A Cole-Strauss, L Marshall, ... Proceedings of the National Academy of Sciences 116 (12), 5765-5774, 2019 | 90 | 2019 |
| DNA unmethylome profiling by covalent capture of CpG sites E Kriukienė, V Labrie, T Khare, G Urbanavičiūtė, A Lapinaitė, ... Nature communications 4 (1), 2190, 2013 | 78 | 2013 |
| Gut microbiota dysbiosis is associated with elevated bile acids in Parkinson’s disease P Li, BA Killinger, E Ensink, I Beddows, A Yilmaz, N Lubben, J Lamp, ... Metabolites 11 (1), 29, 2021 | 76 | 2021 |
| Mutant mice with reduced NMDA-NR1 glycine affinity or lack of D-amino acid oxidase function exhibit altered anxiety-like behaviors V Labrie, SJ Clapcote, JC Roder Pharmacology Biochemistry and Behavior 91 (4), 610-620, 2009 | 76 | 2009 |
| Epigenomic analysis of Parkinson’s disease neurons identifies Tet2 loss as neuroprotective LL Marshall, BA Killinger, E Ensink, P Li, KX Li, W Cui, N Lubben, ... Nature neuroscience 23 (10), 1203-1214, 2020 | 64 | 2020 |
| Cytosine modifications exhibit circadian oscillations that are involved in epigenetic diversity and aging G Oh, S Ebrahimi, M Carlucci, A Zhang, A Nair, DE Groot, V Labrie, P Jia, ... Nature communications 9 (1), 644, 2018 | 63 | 2018 |
