| Therapeutic uses of furin and its inhibitors: a patent review F Couture, A Kwiatkowska, YL Dory, R Day Expert opinion on therapeutic patents 25 (4), 379-396, 2015 | 86 | 2015 |
| The Multi-Leu peptide inhibitor discriminates between PACE4 and furin and exhibits antiproliferative effects on prostate cancer cells C Levesque, M Fugère, A Kwiatkowska, F Couture, R Desjardins, ... Journal of Medicinal Chemistry 55 (23), 10501-10511, 2012 | 57 | 2012 |
| PACE4 undergoes an oncogenic alternative splicing switch in cancer F Couture, R Sabbagh, A Kwiatkowska, R Desjardins, SP Guay, ... Cancer Research 77 (24), 6863-6879, 2017 | 49 | 2017 |
| Design, synthesis, and structureactivity relationship studies of a potent PACE4 inhibitor A Kwiatkowska, F Couture, C Levesque, K Ly, R Desjardins, ... Journal of medicinal chemistry 57 (1), 98-109, 2014 | 42 | 2014 |
| PACE4 inhibitors and their peptidomimetic analogs block prostate cancer tumor progression through quiescence induction, increased apoptosis and impaired neovascularisation C Levesque, F Couture, A Kwiatkowska, R Desjardins, B Guérin, ... Oncotarget 6 (6), 3680, 2015 | 37 | 2015 |
| Implications of proprotein convertases in ovarian cancer cell proliferation and tumor progression: insights for PACE4 as a therapeutic target R Longuespée, F Couture, C Levesque, A Kwiatkowska, R Desjardins, ... Translational Oncology 7 (3), 410-419, 2014 | 37 | 2014 |
| Optimization of furin inhibitors to protect against the activation of influenza hemagglutinin H5 and Shiga toxin H Gagnon, S Beauchemin, A Kwiatkowska, F Couture, F DAnjou, ... Journal of Medicinal Chemistry 57 (1), 29-41, 2014 | 36 | 2014 |
| Trypsin inhibitors from the garden four oclock (Mirabilis jalapa) and spinach (Spinacia oleracea) seeds: isolation, characterization and chemical synthesis J Kowalska, K Pszczoła, A Wilimowska-Pelc, I Lorenc-Kubis, E Zuziak, ... Phytochemistry 68 (11), 1487-1496, 2007 | 31 | 2007 |
| PACE4 is an important driver of ZR-75-1 estrogen receptor-positive breast cancer proliferation and tumor progression F Panet, F Couture, A Kwiatkowska, R Desjardins, B Guérin, R Day European journal of cell biology 96 (5), 469-475, 2017 | 24 | 2017 |
| Arginine vasopressin and its analoguesThe influence of position 2 modification with 3, 3-diphenylalanine enantiomers. Highly potent V2 agonists A Kwiatkowska, D Sobolewski, A Prahl, L Borovičková, J Slaninová, ... European journal of medicinal chemistry 44 (7), 2862-2867, 2009 | 20 | 2009 |
| Membrane structure and interactions of peptide hormones with model lipid bilayers E Sikorska, E Iłowska, D Wyrzykowski, A Kwiatkowska Biochimica et Biophysica Acta (BBA)-Biomembranes 1818 (12), 2982-2993, 2012 | 17 | 2012 |
| Novel Insights into StructureActivity Relationships of N‐Terminally Modified PACE4 Inhibitors A Kwiatkowska, F Couture, C Levesque, K Ly, S Beauchemin, ... ChemMedChem 11 (3), 289-301, 2016 | 16 | 2016 |
| NMR studies of new arginine vasopressin analogs modified with α-2-indanylglycine enantiomers at position 2 bound to sodium dodecyl sulfate micelles E Lubecka, A Kwiatkowska, J Ciarkowski, E Sikorska Biophysical chemistry 151 (3), 139-148, 2010 | 12 | 2010 |
| Enhanced anti-tumor activity of the Multi-Leu peptide PACE4 inhibitor transformed into an albumin-bound tumor-targeting prodrug A Kwiatkowska, F Couture, S Ait-Mohand, R Desjardins, YL Dory, ... Scientific Reports 9 (1), 2118, 2019 | 10 | 2019 |
| Rational design of a highly potent and selective peptide inhibitor of PACE4 by salt bridge interaction with D160 at position P3 V Dianati, A Shamloo, A Kwiatkowska, R Desjardins, A Soldera, R Day, ... ChemMedChem 12 (15), 1169-1172, 2017 | 10 | 2017 |
| Macrocyclization of a potent PACE4 inhibitor: Benefits and limitations T Łepek, A Kwiatkowska, F Couture, K Ly, R Desjardins, Y Dory, A Prahl, ... European journal of cell biology 96 (5), 476-485, 2017 | 10 | 2017 |
| Positional scanning identifies the molecular determinants of a high affinity multi-leucine inhibitor for furin and PACE4 I Małuch, C Levesque, A Kwiatkowska, F Couture, K Ly, R Desjardins, ... Journal of Medicinal Chemistry 60 (7), 2732-2744, 2017 | 10 | 2017 |
| Influence of bulky 3, 3′-diphenylalanine enantiomers replacing position 2 of AVP analogues on their conformations: NMR and molecular modeling studies E Sikorska, A Kwiatkowska, D Sobolewski, R Ślusarz, MJ Ślusarz European journal of medicinal chemistry 45 (9), 4065-4073, 2010 | 10 | 2010 |
| The path to therapeutic furin inhibitors: From yeast pheromones to SARS-CoV-2 G Thomas, F Couture, A Kwiatkowska International Journal of Molecular Sciences 23 (7), 3435, 2022 | 8 | 2022 |
| Design and StructureActivity Relationship of a Potent Furin Inhibitor Derived from Influenza Hemagglutinin MA Lewandowska-Goch, A Kwiatkowska, T Łepek, K Ly, P Navals, ... ACS Medicinal Chemistry Letters 12 (3), 365-372, 2021 | 8 | 2021 |
Robert Day PhDPhenoswitch Bioscience IncPatvirtintas el. paštas psbinc.ca
