| Chemical genetic control of protein levels: selective in vivo targeted degradation JS Schneekloth Jr, FN Fonseca, M Koldobskiy, A Mandal, R Deshaies, ... Journal of the American Chemical Society 126 (12), 3748-3754, 2004 | 508 | 2004 |
| The emerging role of RNA as a therapeutic target for small molecules CM Connelly, MH Moon, JS Schneekloth Cell chemical biology 23 (9), 1077-1090, 2016 | 289 | 2016 |
| Targeting the RNA polymerase I transcription for cancer therapy comes of age R Ferreira, JS Schneekloth Jr, KI Panov, KM Hannan, RD Hannan Cells 9 (2), 266, 2020 | 150 | 2020 |
| Chemical and structural studies provide a mechanistic basis for recognition of the MYC G-quadruplex DR Calabrese, X Chen, EC Leon, SM Gaikwad, Z Phyo, WM Hewitt, ... Nature communications 9 (1), 4229, 2018 | 142 | 2018 |
| Selective Small-Molecule Targeting of a Triple Helix Encoded by the Long Noncoding RNA, MALAT1 FA Abulwerdi, W Xu, AA Ageeli, MJ Yonkunas, G Arun, H Nam, ... ACS chemical biology 14 (2), 223-235, 2019 | 139 | 2019 |
| Identification of biologically active, HIV TAR RNA-binding small molecules using small molecule microarrays J Sztuba-Solinska, SR Shenoy, P Gareiss, LRH Krumpe, SFJ Le Grice, ... Journal of the American Chemical Society 136 (23), 8402-8410, 2014 | 136 | 2014 |
| Small molecule microarrays enable the identification of a selective, quadruplex-binding inhibitor of MYC expression KM Felsenstein, LB Saunders, JK Simmons, E Leon, DR Calabrese, ... ACS chemical biology 11 (1), 139-148, 2016 | 127 | 2016 |
| Structure and Synthesis of the Natural Heptachloro‐1′‐methyl‐1, 2′‐bipyrrole (Q1) J Wu, W Vetter, GW Gribble, JS Schneekloth, Jr, DH Blank, H Görls Angewandte Chemie International Edition 41 (10), 1740-1743, 2002 | 100 | 2002 |
| Development of small molecules with a noncanonical binding mode to HIV-1 trans activation response (TAR) RNA FA Abulwerdi, MD Shortridge, J Sztuba-Solinska, R Wilson, SFJ Le Grice, ... Journal of medicinal chemistry 59 (24), 11148-11160, 2016 | 93 | 2016 |
| An electrophoretic mobility shift assay identifies a mechanistically unique inhibitor of protein sumoylation YS Kim, K Nagy, S Keyser, JS Schneekloth Chemistry & biology 20 (4), 604-613, 2013 | 89 | 2013 |
| Measuring RNA–ligand interactions with microscale thermophoresis MH Moon, TA Hilimire, AM Sanders, JS Schneekloth Jr Biochemistry 57 (31), 4638-4643, 2018 | 86 | 2018 |
| Discovery of inhibitors of microRNA-21 processing using small molecule microarrays CM Connelly, RE Boer, MH Moon, P Gareiss, JS Schneekloth Jr ACS chemical biology 12 (2), 435-443, 2017 | 78 | 2017 |
| Synthetic ligands for PreQ1 riboswitches provide structural and mechanistic insights into targeting RNA tertiary structure CM Connelly, T Numata, RE Boer, MH Moon, RS Sinniah, JJ Barchi, ... Nature communications 10 (1), 1501, 2019 | 69 | 2019 |
| Synthetic studies on amphidinolide B1 AK Mandal, JS Schneekloth, K Kuramochi, CM Crews Organic letters 8 (3), 427-430, 2006 | 65 | 2006 |
| Synthesis of 2′, 3′, 4′-trihydroxyflavone (2-D08), an inhibitor of protein sumoylation YS Kim, SGL Keyser, JS Schneekloth Jr Bioorganic & medicinal chemistry letters 24 (4), 1094-1097, 2014 | 64 | 2014 |
| Stereoselective Assembly of a 1,3-Diene via Coupling between an Allenic Acetate and a (B)-Alkylborane: Synthetic Studies on Amphidinolide B1 AK Mandal, JS Schneekloth, CM Crews Organic letters 7 (17), 3645-3648, 2005 | 57 | 2005 |
| Targeting the oncogenic long non-coding RNA SLNCR1 by blocking its sequence-specific binding to the androgen receptor K Schmidt, CA Weidmann, TA Hilimire, E Yee, BM Hatfield, ... Cell reports 30 (2), 541-554. e5, 2020 | 52 | 2020 |
| Evidence for ligandable sites in structured RNA throughout the Protein Data Bank WM Hewitt, DR Calabrese, JS Schneekloth Jr Bioorganic & medicinal chemistry 27 (11), 2253-2260, 2019 | 52 | 2019 |
| Chemical approaches to controlling intracellular protein degradation JS Schneekloth Jr, CM Crews Chembiochem: a European journal of chemical biology 6 (1), 40, 2005 | 52 | 2005 |
| Custom DNA microarrays reveal diverse binding preferences of proteins and small molecules to thousands of G-quadruplexes S Ray, D Tillo, RE Boer, N Assad, M Barshai, G Wu, Y Orenstein, D Yang, ... ACS chemical biology 15 (4), 925-935, 2020 | 44 | 2020 |
