Revealing the competition between peeled ssDNA, melting bubbles, and S-DNA during DNA overstretching by single-molecule calorimetry X Zhang, H Chen, S Le, I Rouzina, PS Doyle, J Yan Proceedings of the National Academy of Sciences 110 (10), 3865-3870, 2013 | 163 | 2013 |
Two distinct overstretched DNA structures revealed by single-molecule thermodynamics measurements X Zhang, H Chen, H Fu, PS Doyle, J Yan Proceedings of the National Academy of Sciences 109 (21), 8103-8108, 2012 | 145 | 2012 |
Cisplatin induces loop structures and condensation of single DNA molecules XM Hou, XH Zhang, KJ Wei, C Ji, SX Dou, WC Wang, M Li, PY Wang Nucleic acids research 37 (5), 1400-1410, 2009 | 141 | 2009 |
Transition dynamics and selection of the distinct S-DNA and strand unpeeling modes of double helix overstretching H Fu, H Chen, X Zhang, Y Qu, JF Marko, J Yan Nucleic acids research 39 (8), 3473-3481, 2011 | 117 | 2011 |
Impediment of E. coli UvrD by DNA‐destabilizing force reveals a strained‐inchworm mechanism of DNA unwinding B Sun, KJ Wei, B Zhang, XH Zhang, SX Dou, M Li, XG Xi The EMBO journal 27 (24), 3279-3287, 2008 | 80 | 2008 |
Compaction dynamics of single DNA molecules under tension WB Fu, XL Wang, XH Zhang, SY Ran, J Yan, M Li Journal of the American Chemical Society 128 (47), 15040-15041, 2006 | 64 | 2006 |
A Cas12a ortholog with stringent PAM recognition followed by low off-target editing rates for genome editing P Chen, J Zhou, Y Wan, H Liu, Y Li, Z Liu, H Wang, J Lei, K Zhao, Y Zhang, ... Genome biology 21, 1-13, 2020 | 60 | 2020 |
The mechanical properties of RNA-DNA hybrid duplex stretched by magnetic tweezers C Zhang, H Fu, Y Yang, E Zhou, Z Tan, H You, X Zhang Biophysical journal 116 (2), 196-204, 2019 | 45 | 2019 |
Gemini surfactant-induced DNA condensation into a beadlike structure XL Wang, XH Zhang, M Cao, HZ Zheng, B Xiao, Y Wang, M Li The Journal of Physical Chemistry B 113 (8), 2328-2332, 2009 | 44 | 2009 |
A reversible shearing DNA probe for visualizing mechanically strong receptors in living cells H Li, C Zhang, Y Hu, P Liu, F Sun, W Chen, X Zhang, J Ma, W Wang, ... Nature Cell Biology 23 (6), 642-651, 2021 | 41 | 2021 |
Interconversion between three overstretched DNA structures X Zhang, Y Qu, H Chen, I Rouzina, S Zhang, PS Doyle, J Yan Journal of the American Chemical Society 136 (45), 16073-16080, 2014 | 41 | 2014 |
Structural flexibility of DNA-RNA hybrid duplex: stretching and twist-stretch coupling JH Liu, K Xi, X Zhang, L Bao, X Zhang, ZJ Tan Biophysical journal 117 (1), 74-86, 2019 | 36 | 2019 |
Opposite effects of high-valent cations on the elasticities of DNA and RNA duplexes revealed by magnetic tweezers H Fu, C Zhang, XW Qiang, YJ Yang, L Dai, ZJ Tan, XH Zhang Physical Review Letters 124 (5), 058101, 2020 | 35 | 2020 |
Cytosine methylation enhances DNA condensation revealed by equilibrium measurements using magnetic tweezers YJ Yang, HL Dong, XW Qiang, H Fu, EC Zhou, C Zhang, L Yin, XF Chen, ... Journal of the American Chemical Society 142 (20), 9203-9209, 2020 | 27 | 2020 |
Mechanical force antagonizes the inhibitory effects of RecX on RecA filament formation in Mycobacterium tuberculosis S Le, H Chen, X Zhang, J Chen, KN Patil, K Muniyappa, J Yan Nucleic acids research 42 (19), 11992-11999, 2014 | 22 | 2014 |
Rtt105 promotes high-fidelity DNA replication and repair by regulating the single-stranded DNA-binding factor RPA X Wang, Y Dong, X Zhao, J Li, J Lee, Z Yan, S Yang, W Wu, X Hou, G Liu, ... Proceedings of the National Academy of Sciences 118 (25), e2106393118, 2021 | 13 | 2021 |
High mechanical stability and slow unfolding rates are prevalent in parallel-stranded DNA G-quadruplexes Y Cheng, Y Zhang, Z Gong, X Zhang, Y Li, X Shi, Y Pei, H You The Journal of Physical Chemistry Letters 11 (19), 7966-7971, 2020 | 12 | 2020 |
Detecting the formation kinetics of doxorubicin-DNA interstrand cross-link at the single-molecule level and clinically relevant concentrations of doxorubicin Y Pei, Y Liu, C Xie, X Zhang, H You Analytical chemistry 92 (6), 4504-4511, 2020 | 12 | 2020 |
A universal assay for making DNA, RNA, and RNA–DNA hybrid configurations for single-molecule manipulation in two or three steps without ligation YJ Yang, L Song, XC Zhao, C Zhang, WQ Wu, HJ You, H Fu, EC Zhou, ... ACS Synthetic Biology 8 (7), 1663-1672, 2019 | 11 | 2019 |
Twist-diameter coupling drives DNA twist changes with salt and temperature C Zhang, F Tian, Y Lu, B Yuan, ZJ Tan, XH Zhang, L Dai Science Advances 8 (12), eabn1384, 2022 | 10 | 2022 |