Stebėti
Ebbe Boedtkjer
Ebbe Boedtkjer
Department of Biomedicine, Aarhus University
Patvirtintas el. paštas biomed.au.dk
Pavadinimas
Cituota
Cituota
Metai
The acidic tumor microenvironment as a driver of cancer
E Boedtkjer, SF Pedersen
Annual review of physiology 82, 103-126, 2020
6682020
Physiology, pharmacology and pathophysiology of the pH regulatory transport proteins NHE1 and NBCn1: similarities, differences, and implications for cancer therapy
E Boedtkjer, L Bunch, S F Pedersen
Current pharmaceutical design 18 (10), 1345-1371, 2012
1522012
Regulation and roles of bicarbonate transport in cancer
A Gorbatenko, CW Olesen, E Boedtkjer, SF Pedersen
Frontiers in physiology 5, 73462, 2014
1432014
Disruption of Na+, HCO3− Cotransporter NBCn1 (slc4a7) Inhibits NO-Mediated Vasorelaxation, Smooth Muscle Ca2+ Sensitivity, and Hypertension Development in Mice
E Boedtkjer, J Praetorius, VV Matchkov, E Stankevicius, S Mogensen, ...
Circulation 124 (17), 1819-1829, 2011
1422011
Contribution of Na+,HCO3‐cotransport to cellular pH control in human breast cancer: A role for the breast cancer susceptibility locus NBCn1 (SLC4A7)
E Boedtkjer, JMA Moreira, M Mele, P Vahl, VT Wielenga, PM Christiansen, ...
International journal of cancer 132 (6), 1288-1299, 2013
1272013
NBCn1 and NHE1 expression and activity in ΔNErbB2 receptor-expressing MCF-7 breast cancer cells: contributions to pHi regulation and chemotherapy resistance
G Lauritzen, MBF Jensen, E Boedtkjer, R Dybboe, C Aalkjær, ...
Experimental cell research 316 (15), 2538-2553, 2010
1222010
Antibody-independent localization of the electroneutral Na+-HCO3 cotransporter NBCn1 (slc4a7) in mice
E Boedtkjer, J Praetorius, EM Fuchtbauer, C Aalkjaer
American Journal of Physiology-Cell Physiology 294 (2), C591-C603, 2008
932008
NBCn1 (slc4a7) Mediates the Na+-Dependent Bicarbonate Transport Important for Regulation of Intracellular pH in Mouse Vascular Smooth Muscle Cells
E Boedtkjer, J Praetorius, C Aalkjaer
Circulation research 98 (4), 515-523, 2006
922006
Disrupting Na+,HCO3–-cotransporter NBCn1 (Slc4a7) delays murine breast cancer development
S Lee, TV Axelsen, AP Andersen, P Vahl, SF Pedersen, E Boedtkjer
Oncogene, 2015
822015
The net acid extruders NHE1, NBCn1 and MCT4 promote mammary tumor growth through distinct but overlapping mechanisms
AP Andersen, J Samsøe‐Petersen, EK Oernbo, E Boedtkjer, JMA Moreira, ...
International journal of cancer 142 (12), 2529-2542, 2018
662018
Opening of small and intermediate calcium-activated potassium channels induces relaxation mainly mediated by nitric-oxide release in large arteries and endothelium-derived …
E Stankevičius, T Dalsgaard, C Kroigaard, L Beck, E Boedtkjer, ...
Journal of Pharmacology and Experimental Therapeutics 339 (3), 842-850, 2011
662011
Intracellular pH in the resistance vasculature: regulation and functional implications
E Boedtkjer, C Aalkjaer
Journal of vascular research 49 (6), 479-496, 2012
622012
Na+,HCO3 -cotransport is functionally upregulated during human breast carcinogenesis and required for the inverted pH gradient across the plasma …
S Lee, M Mele, P Vahl, PM Christiansen, VED Jensen, E Boedtkjer
Pflügers Archiv-European Journal of Physiology 467, 367-377, 2015
602015
NHE1 knockout reduces blood pressure and arterial media/lumen ratio with no effect on resting pHi in the vascular wall
E Boedtkjer, HH Damkier, C Aalkjaer
The Journal of physiology 590 (8), 1895-1906, 2012
572012
Cation‐coupled bicarbonate transporters
C Aalkjaer, E Boedtkjer, I Choi, S Lee
Comprehensive Physiology 4 (4), 1605-1637, 2014
552014
Vasomotion has chloride-dependency in rat mesenteric small arteries
DMB Boedtkjer, VV Matchkov, E Bødtkjer, H Nilsson, C Aalkjaer
Pflügers Archiv-European Journal of Physiology 457, 389-404, 2008
532008
Extracellular HCO3- is sensed by mouse cerebral arteries: Regulation of tone by receptor protein tyrosine phosphatase γ
E Boedtkjer, KB Hansen, DMB Boedtkjer, C Aalkjaer, WF Boron
Journal of Cerebral Blood Flow & Metabolism, 0271678X15610787, 2015
49*2015
Na+,HCO3−-cotransporter NBCn1 increases pHi gradients, filopodia, and migration of smooth muscle cells and promotes arterial remodelling
E Boedtkjer, JF Bentzon, VS Dam, C Aalkjaer
Cardiovascular research 111 (3), 227-239, 2016
462016
Insulin inhibits Na+/H+ exchange in vascular smooth muscle and endothelial cells in situ: involvement of H2O2 and tyrosine phosphatase SHP-2
E Boedtkjer, C Aalkjaer
American Journal of Physiology-Heart and Circulatory Physiology 296 (2 …, 2009
452009
Splice cassette II of Na+, HCO3− cotransporter NBCn1 (slc4a7) interacts with calcineurin A: implications for transporter activity and intracellular pH control during rat artery …
AA Danielsen, MD Parker, S Lee, WF Boron, C Aalkjaer, E Boedtkjer
Journal of Biological Chemistry 288 (12), 8146-8155, 2013
43*2013
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Straipsniai 1–20