Erlend Arnulf Nagelhus
Erlend Arnulf Nagelhus
Professor of Medicine, University of Oslo
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A paravascular pathway facilitates CSF flow through the brain parenchyma and the clearance of interstitial solutes, including amyloid β
JJ Iliff, M Wang, Y Liao, BA Plogg, W Peng, GA Gundersen, H Benveniste, ...
Science translational medicine 4 (147), 147ra111-147ra111, 2012
Specialized membrane domains for water transport in glial cells: high-resolution immunogold cytochemistry of aquaporin-4 in rat brain
S Nielsen, EA Nagelhus, M Amiry-Moghaddam, C Bourque, P Agre, ...
Journal of Neuroscience 17 (1), 171-180, 1997
Physiological roles of aquaporin-4 in brain
EA Nagelhus, OP Ottersen
Physiological reviews 93 (4), 1543-1562, 2013
Aquaporin-4 in the central nervous system: cellular and subcellular distribution and coexpression with KIR4. 1
EA Nagelhus, TM Mathiisen, OP Ottersen
Neuroscience 129 (4), 905-913, 2004
Immunogold evidence suggests that coupling of K+ siphoning and water transport in rat retinal Müller cells is mediated by a coenrichment of Kir4.1 and AQP4 in …
EA Nagelhus, Y Horio, A Inanobe, A Fujita, F Haug, S Nielsen, Y Kurachi, ...
Glia 26 (1), 47-54, 1999
Aquaporin-4 water channel protein in the rat retina and optic nerve: polarized expression in Müller cells and fibrous astrocytes
EA Nagelhus, ML Veruki, R Torp, FM Haug, JH Laake, S Nielsen, P Agre, ...
Journal of Neuroscience 18 (7), 2506-2519, 1998
Delayed K+ clearance associated with aquaporin-4 mislocalization: phenotypic defects in brains of α-syntrophin-null mice
M Amiry-Moghaddam, A Williamson, M Palomba, T Eid, NC De Lanerolle, ...
Proceedings of the National Academy of Sciences 100 (23), 13615-13620, 2003
Aquaporins in complex tissues: distribution of aquaporins 1–5 in human and rat eye
S Hamann, T Zeuthen, ML Cour, EA Nagelhus, OP Ottersen, P Agre, ...
American Journal of Physiology-Cell Physiology 274 (5), C1332-C1345, 1998
Glial-conditional deletion of aquaporin-4 (Aqp4) reduces blood–brain water uptake and confers barrier function on perivascular astrocyte endfeet
NN Haj-Yasein, GF Vindedal, M Eilert-Olsen, GA Gundersen, Ĝ Skare, ...
Proceedings of the National Academy of Sciences 108 (43), 17815-17820, 2011
General anesthesia selectively disrupts astrocyte calcium signaling in the awake mouse cortex
AS Thrane, V Rangroo Thrane, D Zeppenfeld, N Lou, Q Xu, EA Nagelhus, ...
Proceedings of the National Academy of Sciences 109 (46), 18974-18979, 2012
Critical role of aquaporin-4 (AQP4) in astrocytic Ca2+ signaling events elicited by cerebral edema
AS Thrane, PM Rappold, T Fujita, A Torres, LK Bekar, T Takano, W Peng, ...
Proceedings of the National Academy of Sciences 108 (2), 846-851, 2011
Impaired glymphatic function and clearance of tau in an Alzheimer’s disease model
IF Harrison, O Ismail, A Machhada, N Colgan, Y Ohene, P Nahavandi, ...
Brain 143 (8), 2576-2593, 2020
Ammonia triggers neuronal disinhibition and seizures by impairing astrocyte potassium buffering
V Rangroo Thrane, AS Thrane, F Wang, ML Cotrina, NA Smith, M Chen, ...
Nature medicine 19 (12), 1643-1648, 2013
Interstitial solute transport in 3D reconstructed neuropil occurs by diffusion rather than bulk flow
KE Holter, B Kehlet, A Devor, TJ Sejnowski, AM Dale, SW Omholt, ...
Proceedings of the National Academy of Sciences 114 (37), 9894-9899, 2017
Ontogeny of water transport in rat brain: Postnatal expression of the aquaporin‐4 water channel
H Wen, EA Nagelhus, M Amiry‐Moghaddam, P Agre, OP Ottersen, ...
European Journal of Neuroscience 11 (3), 935-945, 1999
Paravascular microcirculation facilitates rapid lipid transport and astrocyte signaling in the brain
VR Thrane, AS Thrane, BA Plog, M Thiyagarajan, JJ Iliff, R Deane, ...
Scientific reports 3 (1), 2582, 2013
Aquaporin‐4 and epilepsy
DK Binder, EA Nagelhus, OP Ottersen
Glia 60 (8), 1203-1214, 2012
LTP induction boosts glutamate spillover by driving withdrawal of perisynaptic astroglia
C Henneberger, L Bard, A Panatier, JP Reynolds, O Kopach, ...
Neuron 108 (5), 919-936. e11, 2020
Dynamics of ionic shifts in cortical spreading depression
R Enger, W Tang, GF Vindedal, V Jensen, P Johannes Helm, R Sprengel, ...
Cerebral Cortex 25 (11), 4469-4476, 2015
Evidence that compromised K+ spatial buffering contributes to the epileptogenic effect of mutations in the human kir4.1 gene (KCNJ10)
NN Haj‐Yasein, V Jensen, GF Vindedal, GA Gundersen, A Klungland, ...
Glia 59 (11), 1635-1642, 2011
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