Design of an in vitro biocatalytic cascade for the manufacture of islatravir MA Huffman, A Fryszkowska, O Alvizo, M Borra-Garske, KR Campos, ... Science 366 (6470), 1255-1259, 2019 | 495 | 2019 |
Laboratory evolution of P450 BM3 for mediated electron transfer yielding an activity-improved and reductase-independent variant J Nazor, S Dannenmann, RO Adjei, YB Fordjour, IT Ghampson, ... Protein Engineering, Design & Selection 21 (1), 29-35, 2008 | 90 | 2008 |
Ultra-high-throughput screening method for the directed evolution of glucose oxidase R Ostafe, R Prodanovic, J Nazor, R Fischer Chemistry & biology 21 (3), 414-421, 2014 | 78 | 2014 |
Baeyer–Villiger monooxygenase-mediated synthesis of esomeprazole as an alternative for kagan sulfoxidation YK Bong, S Song, J Nazor, M Vogel, M Widegren, D Smith, SJ Collier, ... The Journal of organic chemistry 83 (14), 7453-7458, 2018 | 68 | 2018 |
Directed evolution of glucose oxidase from Aspergillus niger for ferrocenemethanol‐mediated electron transfer Z Zhu, M Wang, A Gautam, J Nazor, C Momeu, R Prodanovic, ... Biotechnology Journal: Healthcare Nutrition Technology 2 (2), 241-248, 2007 | 68 | 2007 |
Laboratory evolution of P450 BM‐3 for mediated electron transfer J Nazor, U Schwaneberg ChemBioChem 7 (4), 638-644, 2006 | 66 | 2006 |
Enzyme evolution for industrial biocatalytic cascades J Nazor, J Liu, G Huisman Current Opinion in Biotechnology 69, 182-190, 2021 | 57 | 2021 |
Engineered imine reductases and methods for the reductive amination of ketone and amine compounds H Chen, SJ Collier, J Nazor, J Sukumaran, D Smith, JC Moore, G Hughes, ... US Patent 9,487,760, 2016 | 52 | 2016 |
Synthesis of prazole compounds YK Bong, MD Clay, SJ Collier, B Mijts, M Vogel, X Zhang, J Zhu, J Nazor, ... | 49 | 2011 |
A chemoenzymatic strategy for site-selective functionalization of native peptides and proteins A Fryszkowska, C An, O Alvizo, G Banerjee, KA Canada, Y Cao, ... Science 376 (6599), 1321-1327, 2022 | 34 | 2022 |
Production of fatty alcohols from engineered microorganisms K Chan, F Valle, Y Barak, L Clark, K Karlshoej, J Vroom, J Nazor, ... US Patent 9,714,437, 2017 | 33 | 2017 |
Biocatalysts and methods for synthesizing derivatives of tryptamine and tryptamine analogs J Nazor, D Smith, M Crowe, S Song, SJ Collier US Patent 9,139,821, 2015 | 16 | 2015 |
Polynucleotides encoding engineered imine reductases H Chen, SJ Collier, J Nazor, J Sukumaran, D Smith, JC Moore, G Hughes, ... US Patent 9,695,451, 2017 | 13 | 2017 |
Engineered imine reductases and methods for the reductive amination of ketone and amine compounds H Chen, SJ Collier, J Nazor, J Sukumaran, D Smith, JC Moore, G Hughes, ... US Patent 9,296,993, 2016 | 13 | 2016 |
Engineered imine reductases and methods for the reductive amination of ketone and amine compounds H Chen, SJ Collier, J Nazor, J Sukumaran, D Smith, JC Moore, G Hughes, ... US Patent 9,828,614, 2017 | 10 | 2017 |
Biocatalysts and methods for synthesizing derivatives of tryptamine and tryptamine analogs J Nazor, D Smith, M Crowe, S Song, SJ Collier US Patent 9,388,395, 2016 | 10 | 2016 |
Synthesis of prazole compounds YK Bong, MD Clay, SJ Collier, B Mijts, M Vogel, X Zhang, J Zhu, J Nazor, ... US Patent 8,895,271, 2014 | 10 | 2014 |
Biocatalysts and methods for hydroxylation of chemical compounds J Nazor, R Osborne, J Liang, J VROOM, X Zhang, D Entwistle, R Voladri, ... | 9 | 2017 |
Chemical process for preparing spiroindolones and intermediates thereof M Crowe, M Foulkes, G Francese, D Grimler, E Kuesters, K Laumen, Y Li, ... | 8 | 2023 |
Biocatalysts and methods for hydroxylation of chemical compounds J Nazor, R Osborne, J Liang, J Vroom, X Zhang, D Entwistle, R Voladri, ... US Patent 10,184,117, 2019 | 8 | 2019 |