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Jure Borišek
Jure Borišek
National Institute of Chemistry
Verified email at ki.si
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Year
Decrypting the information exchange pathways across the spliceosome machinery
A Saltalamacchia, L Casalino, J Borisek, VS Batista, I Rivalta, ...
Journal of the American Chemical Society 142 (18), 8403-8411, 2020
352020
Allosteric cross-talk among spike’s receptor-binding domain mutations of the SARS-CoV-2 South African variant triggers an effective hijacking of human cell receptor
A Spinello, A Saltalamacchia, J Borišek, A Magistrato
The Journal of Physical Chemistry Letters 12 (25), 5987-5993, 2021
312021
Senescent cells as promising targets to tackle age-related diseases
E Prašnikar, J Borišek, A Perdih
Ageing Research Reviews 66, 101251, 2021
302021
Peptide inhibitors of bacterial protein synthesis with broad spectrum and SbmA-independent bactericidal activity against clinical pathogens
M Mardirossian, R Sola, B Beckert, E Valencic, DWP Collis, J Borišek, ...
Journal of medicinal chemistry 63 (17), 9590-9602, 2020
302020
The CWB2 cell wall-anchoring module is revealed by the crystal structures of the Clostridium difficile cell wall proteins Cwp8 and Cwp6
A Usenik, M Renko, M Mihelič, N Lindič, J Borišek, A Perdih, G Pretnar, ...
Structure 25 (3), 514-521, 2017
302017
Disclosing the impact of carcinogenic SF3b mutations on pre-mRNA recognition via all-atom simulations
J Borišek, A Saltalamacchia, A Gallì, G Palermo, E Molteni, L Malcovati, ...
Biomolecules 9 (10), 633, 2019
292019
Exploiting cryo-EM structural information and all-atom simulations to decrypt the molecular mechanism of splicing modulators
J Borisek, A Saltalamacchia, A Spinello, A Magistrato
Journal of Chemical Information and Modeling 60 (5), 2510-2521, 2019
292019
All-atom simulations decrypt the molecular terms of RNA catalysis in the exon-ligation step of the spliceosome
J Borišek, A Magistrato
ACS Catalysis 10 (9), 5328-5334, 2020
282020
Atomic-level mechanism of Pre-mRNA splicing in health and disease
J Borisek, L Casalino, A Saltalamacchia, SG Mays, L Malcovati, ...
Accounts of Chemical Research 54 (1), 144-154, 2020
262020
Development of N-(Functionalized benzoyl)-homocycloleucyl-glycinonitriles as Potent Cathepsin K Inhibitors
J Borisek, M Vizovisek, P Sosnowski, B Turk, D Turk, B Mohar, M Novic
Journal of medicinal chemistry 58 (17), 6928-6937, 2015
262015
Molecular basis for functional diversity among microbial Nep1-like proteins
T Lenarčič, K Pirc, V Hodnik, I Albert, J Borišek, A Magistrato, ...
PLoS pathogens 15 (9), e1007951, 2019
242019
The comparison of docking search algorithms and scoring functions: an overview and case studies
M Novič, T Tibaut, M Anderluh, J Borišek, T Tomašič
Methods and algorithms for molecular docking-based drug design and discovery …, 2016
162016
A Water-Assisted Catalytic Mechanism in Glycoside Hydrolases Demonstrated on the Staphylococcus aureus Autolysin E
J Borišek, S Pintar, M Ogrizek, D Turk, A Perdih, M Novič
ACS Catalysis 8 (5), 4334-4345, 2018
132018
An oomycete NLP cytolysin forms transient small pores in lipid membranes
K Pirc, LA Clifton, N Yilmaz, A Saltalamacchia, M Mally, T Snoj, ...
Science Advances 8 (10), eabj9406, 2022
122022
Mechanistic interpretation of artificial neural network‐based QSAR model for prediction of cathepsin K inhibition potency
J Borišek, V Drgan, N Minovski, M Novič
Journal of Chemometrics 28 (4), 272-281, 2014
112014
Nep1-like proteins as a target for plant pathogen control
K Pirc, V Hodnik, T Snoj, T Lenarčič, S Caserman, M Podobnik, H Böhm, ...
PLoS Pathogens 17 (4), e1009477, 2021
102021
Investigating the molecular mechanism of H3B-8800: a splicing modulator inducing preferential lethality in spliceosome-mutant cancers
A Spinello, J Borišek, L Malcovati, A Magistrato
International Journal of Molecular Sciences 22 (20), 11222, 2021
92021
Computing metal‐binding proteins for therapeutic benefit
A Spinello, J Borišek, M Pavlin, P Janoš, A Magistrato
ChemMedChem 16 (13), 2034-2049, 2021
92021
Comparison of in silico tools for binding site prediction applied for structure-based design of autolysin inhibitors
T Tibaut, J Borišek, M Novič, D Turk
SAR and QSAR in Environmental Research 27 (7), 573-587, 2016
92016
Establishing the catalytic and regulatory mechanism of RNA‐based machineries
J Borišek, J Aupič, A Magistrato
Wiley Interdisciplinary Reviews: Computational Molecular Science 13 (3), e1643, 2023
82023
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