SwissTargetPrediction: a web server for target prediction of bioactive small molecules D Gfeller, A Grosdidier, M Wirth, A Daina, O Michielin, V Zoete Nucleic acids research 42 (W1), W32-W38, 2014 | 1438 | 2014 |
Intratumoral Tcf1+ PD-1+ CD8+ T cells with stem-like properties promote tumor control in response to vaccination and checkpoint blockade immunotherapy I Siddiqui, K Schaeuble, V Chennupati, SAF Marraco, S Calderon-Copete, ... Immunity 50 (1), 195-211. e10, 2019 | 1274 | 2019 |
Simultaneous enumeration of cancer and immune cell types from bulk tumor gene expression data J Racle, K de Jonge, P Baumgaertner, DE Speiser, D Gfeller elife 6, e26476, 2017 | 1046 | 2017 |
Shaping the interaction landscape of bioactive molecules D Gfeller, O Michielin, V Zoete Bioinformatics 29 (23), 3073-3079, 2013 | 498 | 2013 |
Personalized cancer vaccine effectively mobilizes antitumor T cell immunity in ovarian cancer JL Tanyi, S Bobisse, E Ophir, S Tuyaerts, A Roberti, R Genolet, ... Science translational medicine 10 (436), eaao5931, 2018 | 420 | 2018 |
Key parameters of tumor epitope immunogenicity revealed through a consortium approach improve neoantigen prediction DK Wells, MM van Buuren, KK Dang, VM Hubbard-Lucey, KCF Sheehan, ... Cell 183 (3), 818-834. e13, 2020 | 407 | 2020 |
EPIC: a tool to estimate the proportions of different cell types from bulk gene expression data J Racle, D Gfeller Bioinformatics for cancer immunotherapy: methods and protocols, 233-248, 2020 | 375 | 2020 |
Deciphering HLA-I motifs across HLA peptidomes improves neo-antigen predictions and identifies allostery regulating HLA specificity M Bassani-Sternberg, C Chong, P Guillaume, M Solleder, HS Pak, ... PLoS computational biology 13 (8), e1005725, 2017 | 258 | 2017 |
Robust prediction of HLA class II epitopes by deep motif deconvolution of immunopeptidomes J Racle, J Michaux, GA Rockinger, M Arnaud, S Bobisse, C Chong, ... Nature biotechnology 37 (11), 1283-1286, 2019 | 255 | 2019 |
Functional complexes between YAP2 and ZO-2 are PDZ domain-dependent, and regulate YAP2 nuclear localization and signalling T Oka, E Remue, K Meerschaert, B Vanloo, C Boucherie, D Gfeller, ... Biochemical Journal 432 (3), 461-478, 2010 | 239 | 2010 |
Tumor-specific cytolytic CD4 T cells mediate immunity against human cancer A Cachot, M Bilous, YC Liu, X Li, M Saillard, M Cenerenti, GA Rockinger, ... Science advances 7 (9), eabe3348, 2021 | 224 | 2021 |
Bayesian modeling of the yeast SH3 domain interactome predicts spatiotemporal dynamics of endocytosis proteins R Tonikian, X Xin, CP Toret, D Gfeller, C Landgraf, S Panni, S Paoluzi, ... PLoS biology 7 (10), e1000218, 2009 | 217 | 2009 |
Tumour-derived PGD2 and NKp30-B7H6 engagement drives an immunosuppressive ILC2-MDSC axis S Trabanelli, MF Chevalier, A Martinez-Usatorre, A Gomez-Cadena, ... Nature communications 8 (1), 593, 2017 | 208 | 2017 |
High-throughput and sensitive immunopeptidomics platform reveals profound interferonγ-mediated remodeling of the human leukocyte antigen (HLA) ligandome C Chong, F Marino, HS Pak, J Racle, RT Daniel, M Müller, D Gfeller, ... Molecular & Cellular Proteomics 17 (3), 533-548, 2018 | 205 | 2018 |
ILC2-modulated T cell–to-MDSC balance is associated with bladder cancer recurrence MF Chevalier, S Trabanelli, J Racle, B Salomé, V Cesson, D Gharbi, ... The Journal of clinical investigation 127 (8), 2916-2929, 2017 | 203 | 2017 |
Complex network analysis of free-energy landscapes D Gfeller, P De Los Rios, A Caflisch, F Rao Proceedings of the National Academy of Sciences 104 (6), 1817-1822, 2007 | 200 | 2007 |
Spectral coarse graining of complex networks D Gfeller, P De Los Rios Physical review letters 99 (3), 038701, 2007 | 174 | 2007 |
Finding instabilities in the community structure of complex networks D Gfeller, JC Chappelier, P De Los Rios Physical Review E—Statistical, Nonlinear, and Soft Matter Physics 72 (5 …, 2005 | 169 | 2005 |
Predicting antigen presentation—what could we learn from a million peptides? D Gfeller, M Bassani-Sternberg Frontiers in immunology 9, 1716, 2018 | 164 | 2018 |
Sensitive and frequent identification of high avidity neo-epitope specific CD8+ T cells in immunotherapy-naive ovarian cancer S Bobisse, R Genolet, A Roberti, JL Tanyi, J Racle, BJ Stevenson, C Iseli, ... Nature communications 9 (1), 1092, 2018 | 156 | 2018 |