Gregory Stephanopoulos
Gregory Stephanopoulos
W.H. Dow Professor of Chemical Engineering and Biotechnology
Verified email at
Cited by
Cited by
Metabolic engineering: principles and methodologies
G Stephanopoulos, AA Aristidou, J Nielsen
Elsevier, 1998
Engineering cell shape and function
R Singhvi, A Kumar, GP Lopez, GN Stephanopoulos, DIC Wang, ...
Science 264 (5159), 696-698, 1994
Reductive glutamine metabolism by IDH1 mediates lipogenesis under hypoxia
CM Metallo, PA Gameiro, EL Bell, KR Mattaini, J Yang, K Hiller, ...
Nature 481 (7381), 380-384, 2012
Isoprenoid pathway optimization for Taxol precursor overproduction in Escherichia coli
PK Ajikumar, WH Xiao, KEJ Tyo, Y Wang, F Simeon, E Leonard, O Mucha, ...
Science 330 (6000), 70-74, 2010
Phosphoglycerate dehydrogenase diverts glycolytic flux and contributes to oncogenesis
JW Locasale, AR Grassian, T Melman, CA Lyssiotis, KR Mattaini, AJ Bass, ...
Nature genetics 43 (9), 869-874, 2011
Tuning genetic control through promoter engineering
H Alper, C Fischer, E Nevoigt, G Stephanopoulos
Proceedings of the National Academy of Sciences 102 (36), 12678-12683, 2005
Engineering yeast transcription machinery for improved ethanol tolerance and production
H Alper, J Moxley, E Nevoigt, GR Fink, G Stephanopoulos
Science 314 (5805), 1565-1568, 2006
Challenges in engineering microbes for biofuels production
G Stephanopoulos
Science 315 (5813), 801-804, 2007
Metabolic fluxes and metabolic engineering
G Stephanopoulos
Metabolic engineering 1 (1), 1-11, 1999
Pyruvate kinase M2 activators promote tetramer formation and suppress tumorigenesis
D Anastasiou, Y Yu, WJ Israelsen, JK Jiang, MB Boxer, BS Hong, ...
Nature chemical biology 8 (10), 839-847, 2012
Transcriptional control of autophagy–lysosome function drives pancreatic cancer metabolism
RM Perera, S Stoykova, BN Nicolay, KN Ross, J Fitamant, M Boukhali, ...
Nature 524 (7565), 361-365, 2015
Network rigidity and metabolic engineering in metabolite overproduction
G Stephanopoulos, JJ Vallino
Science 252 (5013), 1675-1681, 1991
Engineering the push and pull of lipid biosynthesis in oleaginous yeast Yarrowia lipolytica for biofuel production
M Tai, G Stephanopoulos
Metabolic engineering 15, 1-9, 2013
Metabolic flux distributions in Corynebacterium glutamicum during growth and lysine overproduction
JJ Vallino, G Stephanopoulos
Biotechnology and bioengineering 67 (6), 872-885, 2000
Distributing a metabolic pathway among a microbial consortium enhances production of natural products
K Zhou, K Qiao, S Edgar, G Stephanopoulos
Nature biotechnology 33 (4), 377-383, 2015
Elementary metabolite units (EMU): a novel framework for modeling isotopic distributions
MR Antoniewicz, JK Kelleher, G Stephanopoulos
Metabolic engineering 9 (1), 68-86, 2007
The mTORC1 pathway stimulates glutamine metabolism and cell proliferation by repressing SIRT4
A Csibi, SM Fendt, C Li, G Poulogiannis, AY Choo, DJ Chapski, SM Jeong, ...
Cell 153 (4), 840-854, 2013
A roadmap for interpreting 13C metabolite labeling patterns from cells
JM Buescher, MR Antoniewicz, LG Boros, SC Burgess, H Brunengraber, ...
Current opinion in biotechnology 34, 189-201, 2015
Identifying gene targets for the metabolic engineering of lycopene biosynthesis in Escherichia coli
H Alper, YS Jin, JF Moxley, G Stephanopoulos
Metabolic engineering 7 (3), 155-164, 2005
Construction of lycopene-overproducing E. coli strains by combining systematic and combinatorial gene knockout targets
H Alper, K Miyaoku, G Stephanopoulos
Nature biotechnology 23 (5), 612-616, 2005
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