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Alexandra Mazharian
Alexandra Mazharian
Research Fellow
Verified email at efs.sante.fr
Title
Cited by
Cited by
Year
Src family kinases: at the forefront of platelet activation
YA Senis, A Mazharian, J Mori
Blood, The Journal of the American Society of Hematology 124 (13), 2013-2024, 2014
3102014
The tyrosine phosphatase CD148 is an essential positive regulator of platelet activation and thrombosis
YA Senis, MG Tomlinson, S Ellison, A Mazharian, J Lim, Y Zhao, ...
Blood, The Journal of the American Society of Hematology 113 (20), 4942-4954, 2009
1582009
JAK2V617F leads to intrinsic changes in platelet formation and reactivity in a knock-in mouse model of essential thrombocythemia
CM Hobbs, H Manning, C Bennett, L Vasquez, S Severin, L Brain, ...
Blood, The Journal of the American Society of Hematology 122 (23), 3787-3797, 2013
1332013
Dasatinib enhances megakaryocyte differentiation but inhibits platelet formation
A Mazharian, C Ghevaert, L Zhang, S Massberg, SP Watson
Blood, The Journal of the American Society of Hematology 117 (19), 5198-5206, 2011
1032011
Critical role for ERK1/2 in bone marrow and fetal liver–derived primary megakaryocyte differentiation, motility, and proplatelet formation
A Mazharian, SP Watson, S Séverin
Experimental hematology 37 (10), 1238-1249. e5, 2009
1032009
The mitogen‐activated protein kinase signaling pathways: role in megakaryocyte differentiation
S Severin, C Ghevaert, A Mazharian
Journal of Thrombosis and Haemostasis 8 (1), 17-26, 2010
942010
Megakaryocyte-specific deletion of the protein-tyrosine phosphatases Shp1 and Shp2 causes abnormal megakaryocyte development, platelet production, and function
A Mazharian, J Mori, YJ Wang, S Heising, BG Neel, SP Watson, YA Senis
Blood, The Journal of the American Society of Hematology 121 (20), 4205-4220, 2013
922013
Mice lacking the ITIM-containing receptor G6b-B exhibit macrothrombocytopenia and aberrant platelet function
A Mazharian, YJ Wang, J Mori, D Bem, B Finney, S Heising, P Gissen, ...
Science signaling 5 (248), ra78-ra78, 2012
792012
Protease-activating receptor-4 induces full platelet spreading on a fibrinogen matrix: involvement of ERK2 and p38 and Ca2+ mobilization
A Mazharian, E Berrou, A Kauskot, P Nurden, M Jandrot-Perrus, ...
Journal of biological chemistry 282 (8), 5478-5487, 2007
792007
Critical role of Src-Syk-PLCγ2 signaling in megakaryocyte migration and thrombopoiesis
A Mazharian, SG Thomas, TS Dhanjal, CD Buckley, SP Watson
Blood, The Journal of the American Society of Hematology 116 (5), 793-800, 2010
632010
Differential involvement of ERK2 and p38 in platelet adhesion to collagen
A Mazharian, S Roger, P Maurice, E Berrou, MR Popoff, MF Hoylaerts, ...
Journal of Biological Chemistry 280 (28), 26002-26010, 2005
632005
Sphingosine kinase 2 (Sphk2) regulates platelet biogenesis by providing intracellular sphingosine 1-phosphate (S1P)
L Zhang, N Urtz, F Gaertner, KR Legate, T Petzold, M Lorenz, ...
Blood, The Journal of the American Society of Hematology 122 (5), 791-802, 2013
622013
Cyclin D3 is a cofactor of retinoic acid receptors, modulating their activity in the presence of cellular retinoic acid-binding protein II
G Despouy, JN Bastie, S Deshaies, N Balitrand, A Mazharian, ...
Journal of Biological Chemistry 278 (8), 6355-6362, 2003
522003
The Gp1ba-Cre transgenic mouse: a new model to delineate platelet and leukocyte functions
Z Nagy, T Vögtle, MJ Geer, J Mori, S Heising, G Di Nunzio, R Gareus, ...
Blood, The Journal of the American Society of Hematology 133 (4), 331-343, 2019
492019
Involvement of the mitogen-activated protein kinase c-Jun NH2-terminal kinase 1 in thrombus formation
A Kauskot, F Adam, A Mazharian, N Ajzenberg, E Berrou, A Bonnefoy, ...
Journal of biological chemistry 282 (44), 31990-31999, 2007
492007
Heparan sulfates are critical regulators of the inhibitory megakaryocyte-platelet receptor G6b-B
T Vögtle, S Sharma, J Mori, Z Nagy, D Semeniak, C Scandola, MJ Geer, ...
Elife 8, e46840, 2019
472019
TREM-like transcript 1: a more sensitive marker of platelet activation than P-selectin in humans and mice
CW Smith, Z Raslan, L Parfitt, AO Khan, P Patel, YA Senis, A Mazharian
Blood advances 2 (16), 2072-2078, 2018
432018
Maintenance of murine platelet homeostasis by the kinase Csk and phosphatase CD148
J Mori, Z Nagy, G Di Nunzio, CW Smith, MJ Geer, R Al Ghaithi, ...
Blood, The Journal of the American Society of Hematology 131 (10), 1122-1144, 2018
382018
Congenital macrothrombocytopenia with focal myelofibrosis due to mutations in human G6b-B is rescued in humanized mice
I Hofmann, MJ Geer, T Vögtle, A Crispin, DR Campagna, A Barr, ...
Blood, The Journal of the American Society of Hematology 132 (13), 1399-1412, 2018
372018
Mice lacking the inhibitory collagen receptor LAIR-1 exhibit a mild thrombocytosis and hyperactive platelets
CW Smith, SG Thomas, Z Raslan, P Patel, M Byrne, M Lordkipanidzé, ...
Arteriosclerosis, thrombosis, and vascular biology 37 (5), 823-835, 2017
372017
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