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Jessica J Field
Jessica J Field
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Year
Molecular mechanism of action of microtubule-stabilizing anticancer agents
AE Prota, K Bargsten, D Zurwerra, JJ Field, JF Díaz, KH Altmann, ...
Science 339 (6119), 587-590, 2013
5082013
Microtubule-targeting agents are clinically successful due to both mitotic and interphase impairment of microtubule function
JJ Field, A Kanakkanthara, JH Miller
Bioorganic & medicinal chemistry 22 (18), 5050-5059, 2014
2612014
The binding sites of microtubule-stabilizing agents
JJ Field, JF Díaz, JH Miller
Chemistry & biology 20 (3), 301-315, 2013
1432013
Microtubule-Stabilizing Activity of Zampanolide, a Potent Macrolide Isolated from the Tongan Marine Sponge Cacospongia mycofijiensis
JJ Field, AJ Singh, A Kanakkanthara, T Halafihi, PT Northcote, JH Miller
Journal of medicinal chemistry 52 (22), 7328-7332, 2009
1202009
Zampanolide, a potent new microtubule-stabilizing agent, covalently reacts with the taxane luminal site in tubulin α, β-heterodimers and microtubules
JJ Field, B Pera, E Calvo, A Canales, D Zurwerra, C Trigili, ...
Chemistry & biology 19 (6), 686-698, 2012
1032012
Marine invertebrate natural products that target microtubules
JH Miller, JJ Field, A Kanakkanthara, JG Owen, AJ Singh, PT Northcote
Journal of natural products 81 (3), 691-702, 2018
542018
Structurally diverse hamigerans from the New Zealand marine sponge Hamigera tarangaensis: NMR-directed isolation, structure elucidation and antifungal activity
AJ Singh, JD Dattelbaum, JJ Field, Z Smart, EF Woolly, JM Barber, ...
Organic & Biomolecular Chemistry 11 (46), 8041-8051, 2013
392013
Polyhalogenated Indoles from the Red Alga Rhodophyllis membranacea: The First Isolation of Bromo-Chloro-Iodo Secondary Metabolites
VH Woolner, CM Jones, JJ Field, NH Fadzilah, AB Munkacsi, JH Miller, ...
Journal of natural products 79 (3), 463-469, 2016
362016
The Nitrogenous Hamigerans: Unusual Amino Acid-Derivatized Aromatic Diterpenoid Metabolites from the New Zealand Marine Sponge Hamigera tarangaensis
JD Dattelbaum, AJ Singh, JJ Field, JH Miller, PT Northcote
The Journal of Organic Chemistry 80 (1), 304-312, 2015
352015
Zampanolide, a microtubule-stabilizing agent, is active in resistant cancer cells and inhibits cell migration
JJ Field, PT Northcote, I Paterson, KH Altmann, JF Díaz, JH Miller
International journal of molecular sciences 18 (5), 971, 2017
302017
A previously undescribed tubulin binder
JJ Field, AB Waight, PD Senter
Proceedings of the National Academy of Sciences 111 (38), 13684-13685, 2014
212014
Use of substitute Nonidet P-40 nonionic detergents in intracellular tubulin polymerization assays for screening of microtubule targeting agents
S Sinha, JJ Field, JH Miller
Biochemistry and Cell Biology 95 (3), 379-384, 2017
192017
βI-tubulin mutations in the laulimalide/peloruside binding site mediate drug sensitivity by altering drug–tubulin interactions and microtubule stability
A Kanakkanthara, MR Rowe, JJ Field, PT Northcote, PH Teesdale-Spittle, ...
Cancer letters 365 (2), 251-260, 2015
192015
Zampanolide binding to tubulin indicates cross-talk of taxane site with colchicine and nucleotide sites
JJ Field, B Pera, JE Gallego, E Calvo, J Rodríguez-Salarichs, ...
Journal of natural products 81 (3), 494-505, 2017
152017
Synthesis of a simplified triazole analogue of pateamine A
AH Cumming, SL Brown, X Tao, C Cuyamendous, JJ Field, JH Miller, ...
Organic & biomolecular chemistry 14 (22), 5117-5127, 2016
132016
31st annual meeting and associated programs of the society for immunotherapy of cancer (Sitc 2016): Part two: National harbor, md, USA. 9-13 November 2016
C Ager, M Reilley, C Nicholas, T Bartkowiak, A Jaiswal, M Curran, ...
Journal for ImmunoTherapy of Cancer 4, 107-221, 2016
122016
Synthesis of Bioactive Side‐Chain Analogues of TAN‐2483B
KK Somarathne, JAJ McCone, A Brackovic, JLP Rivera, JR Fulton, ...
Chemistry–An Asian Journal 14 (8), 1230-1237, 2019
112019
Microtubule-stabilizing properties of the avocado-derived toxins (+)-(R)-persin and (+)-(R)-tetrahydropersin in cancer cells and activity of related synthetic analogs
JJ Field, A Kanakkanthara, DG Brooke, S Sinha, SD Pillai, WA Denny, ...
Investigational new drugs 34, 277-289, 2016
102016
Synthesis of mycothiol conjugate analogues and evaluation of their antimycobacterial activity
SW Riordan, JJ Field, HM Corkran, N Dasyam, BL Stocker, MSM Timmer, ...
Bioorganic & medicinal chemistry letters 25 (10), 2152-2155, 2015
102015
Understanding the mechanism of 2FF-induced immune modulation
JJ Field, NM Okeley, W Zeng, CL Law, PD Senter, SJ Gardai
Cancer Research 76 (14_Supplement), 4005-4005, 2016
82016
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