Martin O. Leonard
Martin O. Leonard
Principal Research Scientist, UK Health Security Agency
Verified email at
Cited by
Cited by
Coordinated adenine nucleotide phosphohydrolysis and nucleoside signaling in posthypoxic endothelium: role of ectonucleotidases and adenosine A2B receptors
HK Eltzschig, JC Ibla, GT Furuta, MO Leonard, KA Jacobson, K Enjyoji, ...
The Journal of experimental medicine 198 (5), 783-796, 2003
MicroRNA-155 promotes resolution of hypoxia-inducible factor 1α activity during prolonged hypoxia
U Bruning, L Cerone, Z Neufeld, SF Fitzpatrick, A Cheong, CC Scholz, ...
Molecular and cellular biology 31 (19), 4087-4096, 2011
Reoxygenation‐specific activation of the antioxidant transcription factor Nrf2 mediates cytoprotective gene expression in ischemia‐reperfusion injury
MO Leonard, NE Kieran, K Howell, MJ Burne, R Varadarajan, ...
The FASEB Journal 20 (14), 2624-2626, 2006
Small ubiquitin-related modifier-1 modification mediates resolution of CREB-dependent responses to hypoxia
KM Comerford, MO Leonard, J Karhausen, R Carey, SP Colgan, ...
Proceedings of the National Academy of Sciences 100 (3), 986-991, 2003
The role of HIF-1α in transcriptional regulation of the proximal tubular epithelial cell response to hypoxia
MO Leonard, DC Cottell, C Godson, HR Brady, CT Taylor
Journal of Biological Chemistry 278 (41), 40296-40304, 2003
Modification of the transcriptomic response to renal ischemia/reperfusion injury by lipoxin analog
NE Kieran, PP Doran, SB Connolly, MC Greenan, DF Higgins, M Leonard, ...
Kidney international 64 (2), 480-492, 2003
BRIEF COMMUNICATION-15-Epi-16-(Para-Fluorophenoxy)-Lipoxin A4-Methyl Ester, a Synthetic Analogue of 15-epi-Lipoxin A4, Is Protective in Experimental Ischemic Acute Renal Failure
MO Leonard, K Hannan, MJ Burne, DWP Lappin, P Doran, P Coleman, ...
Journal of the American Society of Nephrology 13 (6), 1657-1662, 2002
Application of integrated transcriptomic, proteomic and metabolomic profiling for the delineation of mechanisms of drug induced cell stress
A Wilmes, A Limonciel, L Aschauer, K Moenks, C Bielow, MO Leonard, ...
Journal of proteomics 79, 180-194, 2013
An overview of transcriptional regulation in response to toxicological insult
P Jennings, A Limonciel, L Felice, MO Leonard
Archives of toxicology 87, 49-72, 2013
Role of MAP kinase pathways in mediating IL-6 production in human primary mesangial and proximal tubular cells
M Leonard, MP Ryan, AJ Watson, H Schramek, E Healy
Kidney international 56 (4), 1366-1377, 1999
TGF-β superfamily members modulate growth, branching, shaping, and patterning of the ureteric bud
KT Bush, H Sakurai, DL Steer, MO Leonard, RV Sampogna, TN Meyer, ...
Developmental biology 266 (2), 285-298, 2004
Potentiation of glucocorticoid activity in hypoxia through induction of the glucocorticoid receptor
MO Leonard, C Godson, HR Brady, CT Taylor
The Journal of Immunology 174 (4), 2250-2257, 2005
Mechanism of cisplatin proximal tubule toxicity revealed by integrating transcriptomics, proteomics, metabolomics and biokinetics
A Wilmes, C Bielow, C Ranninger, P Bellwon, L Aschauer, A Limonciel, ...
Toxicology in Vitro 30 (1), 117-127, 2015
NF-κB links CO2 sensing to innate immunity and inflammation in mammalian cells
EP Cummins, KM Oliver, CR Lenihan, SF Fitzpatrick, U Bruning, ...
The Journal of Immunology 185 (7), 4439-4445, 2010
Gremlin plays a key role in the pathogenesis of pulmonary hypertension
E Cahill, CM Costello, SC Rowan, S Harkin, K Howell, MO Leonard, ...
Circulation 125 (7), 920-930, 2012
Transforming growth factor‐β‐regulated gene transcription and protein expression in human GFAP‐negative lamina cribrosa cells
RP Kirwan, MO Leonard, M Murphy, AF Clark, CJ O'Brien
Glia 52 (4), 309-324, 2005
Multi-method characterization of the human circulating microbiome
E Whittle, MO Leonard, R Harrison, TW Gant, DP Tonge
Frontiers in microbiology 9, 3266, 2019
Identification and dissection of the Nrf2 mediated oxidative stress pathway in human renal proximal tubule toxicity
A Wilmes, D Crean, S Aydin, W Pfaller, P Jennings, MO Leonard
Toxicology In Vitro 25 (3), 613-622, 2011
Lactate is an ideal non-invasive marker for evaluating temporal alterations in cell stress and toxicity in repeat dose testing regimes
A Limonciel, L Aschauer, A Wilmes, S Prajczer, MO Leonard, W Pfaller, ...
Toxicology in Vitro 25 (8), 1855-1862, 2011
Delineation of the key aspects in the regulation of epithelial monolayer formation
L Aschauer, LN Gruber, W Pfaller, A Limonciel, TJ Athersuch, R Cavill, ...
Molecular and cellular biology 33 (13), 2535-2550, 2013
The system can't perform the operation now. Try again later.
Articles 1–20