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Thomas B. Knudsen
Thomas B. Knudsen
Developmental Systems Biologist, US EPA
Verified email at epa.gov
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Year
Translocator protein (18 kDa): new nomenclature for the peripheral-type benzodiazepine receptor based on its structure and molecular function
V Papadopoulos, M Baraldi, TR Guilarte, TB Knudsen, JJ Lacapère, ...
Trends in pharmacological sciences 27 (8), 402-409, 2006
14342006
Biological stress response terminology: integrating the concepts of adaptive response and preconditioning stress within a hormetic dose–response framework
EJ Calabrese, KA Bachmann, AJ Bailer, PM Bolger, J Borak, L Cai, ...
Toxicology and applied pharmacology 222 (1), 122-128, 2007
7012007
In Vitro Screening of Environmental Chemicals for Targeted Testing Prioritization: The ToxCast Project
RS Judson, KA Houck, RJ Kavlock, TB Knudsen, MT Martin, ...
Environmental health perspectives 118 (4), 485-492, 2010
5482010
ToxCast chemical landscape: paving the road to 21st century toxicology
AM Richard, RS Judson, KA Houck, CM Grulke, P Volarath, ...
Chemical research in toxicology 29 (8), 1225-1251, 2016
4512016
Update on EPA’s ToxCast program: providing high throughput decision support tools for chemical risk management
R Kavlock, K Chandler, K Houck, S Hunter, R Judson, N Kleinstreuer, ...
Chemical research in toxicology 25 (7), 1287-1302, 2012
4432012
Endocrine profiling and prioritization of environmental chemicals using ToxCast data
DM Reif, MT Martin, SW Tan, KA Houck, RS Judson, AM Richard, ...
Environmental health perspectives 118 (12), 1714-1720, 2010
3032010
Zebrafish developmental screening of the ToxCast™ Phase I chemical library
S Padilla, D Corum, B Padnos, DL Hunter, A Beam, KA Houck, N Sipes, ...
Reproductive toxicology 33 (2), 174-187, 2012
2982012
Zebrafish—As an integrative model for twenty‐first century toxicity testing
NS Sipes, S Padilla, TB Knudsen
Birth Defects Research Part C: Embryo Today: Reviews 93 (3), 256-267, 2011
2752011
Integrated Model of Chemical Perturbations of a Biological Pathway Using 18 In Vitro High-Throughput Screening Assays for the Estrogen Receptor
RS Judson, FM Magpantay, V Chickarmane, C Haskell, N Tania, J Taylor, ...
Toxicological Sciences 148 (1), 137-154, 2015
2462015
High-throughput models for exposure-based chemical prioritization in the ExpoCast project
JF Wambaugh, RW Setzer, DM Reif, S Gangwal, J Mitchell-Blackwood, ...
Environmental science & technology 47 (15), 8479-8488, 2013
2382013
A roadmap for the development of alternative (non-animal) methods for systemic toxicity testing
D Basketter, H Clewell, I Kimber, A Rossi, B Blaauboer, R Burrier, ...
2222012
Editor's Highlight: Analysis of the Effects of Cell Stress and Cytotoxicity on In Vitro Assay Activity Across a Diverse Chemical and Assay Space
R Judson, K Houck, M Martin, AM Richard, TB Knudsen, I Shah, S Little, ...
Toxicological Sciences 152 (2), 323-339, 2016
2152016
Estimating toxicity-related biological pathway altering doses for high-throughput chemical risk assessment
RS Judson, RJ Kavlock, RW Setzer, EA Cohen Hubal, MT Martin, ...
Chemical research in toxicology 24 (4), 451-462, 2011
2102011
Analysis of eight oil spill dispersants using rapid, in vitro tests for endocrine and other biological activity
RS Judson, MT Martin, DM Reif, KA Houck, TB Knudsen, DM Rotroff, ...
Environmental science & technology 44 (15), 5979-5985, 2010
2042010
Predictive models of prenatal developmental toxicity from ToxCast high-throughput screening data
NS Sipes, MT Martin, DM Reif, NC Kleinstreuer, RS Judson, AV Singh, ...
Toxicological Sciences 124 (1), 109-127, 2011
1872011
Profiling 976 ToxCast chemicals across 331 enzymatic and receptor signaling assays
NS Sipes, MT Martin, P Kothiya, DM Reif, RS Judson, AM Richard, ...
Chemical research in toxicology 26 (6), 878-895, 2013
1862013
The next generation blueprint of computational toxicology at the US Environmental Protection Agency
RS Thomas, T Bahadori, TJ Buckley, J Cowden, C Deisenroth, ...
Toxicological Sciences 169 (2), 317-332, 2019
1842019
Phenotypic screening of the ToxCast chemical library to classify toxic and therapeutic mechanisms
NC Kleinstreuer, J Yang, EL Berg, TB Knudsen, AM Richard, MT Martin, ...
Nature biotechnology 32 (6), 583-591, 2014
1752014
Consensus report on the future of animal-free systemic toxicity testing
M Leist, N Hasiwa, C Rovida, M Daneshian, D Basketter, I Kimber, ...
Alternatives to Animal Experimentation: ALTEX 31 (3), 341-356, 2014
1612014
Modulation of TLR2 protein expression by miR-105 in human oral keratinocytes
MR Benakanakere, Q Li, MA Eskan, AV Singh, J Zhao, JC Galicia, ...
Journal of biological chemistry 284 (34), 23107-23115, 2009
1602009
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