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Marc Heitz, PhD
Marc Heitz, PhD
Verified email at roche.com - Homepage
Title
Cited by
Cited by
Year
Lipidated peptide dendrimers killing multidrug-resistant bacteria
TN Siriwardena, M Stach, R He, BH Gan, S Javor, M Heitz, L Ma, X Cai, ...
Journal of the American Chemical Society 140 (1), 423-432, 2018
1032018
Stereoselective pH responsive peptide dendrimers for siRNA transfection
M Heitz, S Javor, T Darbre, JL Reymond
Bioconjugate chemistry 30 (8), 2165-2182, 2019
292019
Efficient transfection of siRNA by peptide dendrimer–lipid conjugates
A Kwok, GA Eggimann, M Heitz, JL Reymond, F Hollfelder, T Darbre
ChemBioChem 17 (23), 2223-2229, 2016
262016
Selectivity, efficacy and toxicity studies of UCCB01-144, a dimeric neuroprotective PSD-95 inhibitor
A Bach, BH Clausen, LK Kristensen, MG Andersen, DG Ellman, ...
Neuropharmacology 150, 100-111, 2019
232019
Novel peptide-dendrimer/lipid/oligonucleotide ternary complexes for efficient cellular uptake and improved splice-switching activity
O Saher, CSJ Rocha, EM Zaghloul, OPB Wiklander, S Zamolo, M Heitz, ...
European Journal of Pharmaceutics and Biopharmaceutics 132, 29-40, 2018
212018
Peptide Dendrimer–Lipid Conjugates as DNA and siRNA Transfection Reagents: Role of Charge Distribution Across Generations
M Heitz, A Kwok, GA Eggimann, F Hollfelder, T Darbre, JL Reymond
CHIMIA International Journal for Chemistry 71 (4), 220-225, 2017
162017
Fluorescent peptide Dendrimers for siRNA transfection: tracking pH responsive aggregation, siRNA binding, and cell penetration
M Heitz, S Zamolo, S Javor, JL Reymond
Bioconjugate chemistry 31 (6), 1671-1684, 2020
142020
Lipophilic peptide dendrimers for delivery of splice-switching oligonucleotides
H Daralnakhla, O Saher, S Zamolo, S Bazaz, J P. Bost, M Heitz, ...
Pharmaceutics 13 (1), 116, 2021
72021
Mechanisms of stabilization of proteins by surfactants
TA Khan, DC Gomes, C Grapentin, M Heitz, C Mueller
Surfactants in Biopharmaceutical Development, 59-102, 2023
12023
Enzymatic degradation pattern of polysorbate 20 impacts interfacial properties of monoclonal antibody formulations
K Gregoritza, C Theodorou, M Heitz, T Graf, O Germershaus, M Gregoritza
European Journal of Pharmaceutics and Biopharmaceutics 194, 74-84, 2024
2024
Alternative surfactants as stabilizers for therapeutic protein formulations
M Heitz, T Khan, HS Kientz, C Mueller, JM Pfaff
US Patent App. 18/150,466, 2023
2023
Alternative surfactants as stabilizers for therapeutic protein formulations
Marc HEITZ, Tarik KHAN, Hannah Sophia KIENTZ, Claudia MUELLER, Janina ...
2022
Stereoselective pH Responsive Peptide Dendrimers for Nucleic Acid Transfection
JL Reymond, M Heitz, T Darbre, S Zamolo
DE Patent WO 2021/023891 A1, 2021
2021
Peptide Dendrimers as Nucleic Acid Transfection Reagents
M Heitz
Universität Bern, Philosophisch-naturwissenschaftliche Fakultät, 2018
2018
Frontiers in Medicinal Chemistry 2017 in Bern, Switzerland
D Probst, M Heitz, M Poirier, BH Gan, CØ Delalande, JL Reymond
clinical trials 1, 2, 2017
2017
PEPTIDE DENDRIMER AS SIRNA TRANSFECTION REAGENT
M Heitz, T Darbre, JL Reymond
JOURNAL OF PEPTIDE SCIENCE 22, S108-S110, 2016
2016
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