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Vijaykumar Karuppiah
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Year
Structure of the PilM-PilN inner membrane type IV pilus biogenesis complex from Thermus thermophilus
V Karuppiah, JP Derrick
Journal of Biological Chemistry 286 (27), 24434-24442, 2011
982011
Structure and assembly of an inner membrane platform for initiation of type IV pilus biogenesis
V Karuppiah, RF Collins, A Thistlethwaite, Y Gao, JP Derrick
Proceedings of the National Academy of Sciences 110 (48), E4638-E4647, 2013
652013
Structural basis of catalysis in the bacterial monoterpene synthases linalool synthase and 1, 8-cineole synthase
V Karuppiah, KE Ranaghan, NGH Leferink, LO Johannissen, ...
Acs Catalysis 7 (9), 6268-6282, 2017
572017
Structure and oligomerization of the PilC type IV pilus biogenesis protein from Thermus thermophilus
V Karuppiah, D Hassan, M Saleem, JP Derrick
Proteins: Structure, Function, and Bioinformatics 78 (9), 2049-2057, 2010
572010
Biocatalytic routes to lactone monomers for polymer production
HL Messiha, ST Ahmed, V Karuppiah, R Suardíaz, GA Ascue Avalos, ...
Biochemistry 57 (13), 1997-2008, 2018
452018
Experiment and simulation reveal how mutations in functional plasticity regions guide plant monoterpene synthase product outcome
NGH Leferink, KE Ranaghan, V Karuppiah, A Currin, MW Van Der Kamp, ...
ACS catalysis 8 (5), 3780-3791, 2018
352018
Neuronal calcium sensor-1 binds the D2 dopamine receptor and G-protein-coupled receptor kinase 1 (GRK1) peptides using different modes of interactions
S Pandalaneni, V Karuppiah, M Saleem, LP Haynes, RD Burgoyne, ...
Journal of Biological Chemistry 290 (30), 18744-18756, 2015
342015
Pinpointing a Mechanistic Switch Between Ketoreduction and “Ene” Reduction in Short‐Chain Dehydrogenases/Reductases
A Lygidakis, V Karuppiah, R Hoeven, A Ní Cheallaigh, D Leys, ...
Angewandte Chemie 128 (33), 9748-9752, 2016
312016
Structure and mechanism of the PilF DNA transformation ATPase from Thermus thermophilus
RF Collins, D Hassan, V Karuppiah, A Thistlethwaite, JP Derrick
Biochemical Journal 450 (2), 417-425, 2013
302013
Therapeutic high affinity T cell receptor targeting a KRASG12D cancer neoantigen
A Poole, V Karuppiah, A Hartt, JN Haidar, S Moureau, T Dobrzycki, ...
Nature Communications 13 (1), 5333, 2022
262022
Outer membrane translocons: structural insights into channel formation
V Karuppiah, JL Berry, JP Derrick
Trends in Microbiology 19 (1), 40-48, 2011
242011
Structural insights into the ene-reductase synthesis of profens
J Waller, HS Toogood, V Karuppiah, NJW Rattray, DJ Mansell, D Leys, ...
Organic & Biomolecular Chemistry 15 (20), 4440-4448, 2017
232017
Structure of the Cannabis sativa olivetol‐producing enzyme reveals cyclization plasticity in type III polyketide synthases
LJ Kearsey, N Prandi, V Karuppiah, C Yan, D Leys, H Toogood, E Takano, ...
The FEBS Journal 287 (8), 1511-1524, 2020
222020
Structural cycle of the Thermus thermophilus PilF ATPase: the powering of type IVa pilus assembly
R Collins, V Karuppiah, CA Siebert, R Dajani, A Thistlethwaite, JP Derrick
Scientific Reports 8 (1), 14022, 2018
212018
Structure and properties of a natural competence-associated pilin suggest a unique pilus tip-associated DNA receptor
MZ Salleh, V Karuppiah, M Snee, A Thistlethwaite, CW Levy, D Knight, ...
MBio 10 (3), 10.1128/mbio. 00614-19, 2019
192019
Structures of type IV pilins from Thermus thermophilus demonstrate similarities with type II secretion system pseudopilins
V Karuppiah, A Thistlethwaite, JP Derrick
Journal of Structural Biology 196 (3), 375-384, 2016
152016
Structure and mechanism of the bifunctional CinA enzyme from Thermus thermophilus
V Karuppiah, A Thistlethwaite, R Dajani, J Warwicker, JP Derrick
Journal of Biological Chemistry 289 (48), 33187-33197, 2014
152014
Structure‐guided stabilization of pathogen‐derived peptide‐HLA‐E complexes using non‐natural amino acids conserves native TCR recognition
C Barber, VA De Souza, RL Paterson, M Martin‐Urdiroz, NC Mulakkal, ...
European Journal of Immunology 52 (4), 618-632, 2022
62022
Promiscuous recognition of MR1 drives self-reactive mucosal-associated invariant T cell responses
A Chancellor, R Alan Simmons, RC Khanolkar, V Nosi, A Beshirova, ...
Journal of Experimental Medicine 220 (9), e20221939, 2023
42023
Type IV pili—a numbers game
V Karuppiah, JP Derrick
The EMBO Journal 33 (16), 1732-1734, 2014
22014
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Articles 1–20