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Francesco Simone Ruggeri
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FUS phase separation is modulated by a molecular chaperone and methylation of arginine cation-π interactions
S Qamar, GZ Wang, SJ Randle, FS Ruggeri, JA Varela, JQ Lin, ...
Cell 173 (3), 720-734. e15, 2018
8312018
Infrared nanospectroscopy characterization of oligomeric and fibrillar aggregates during amyloid formation
FS Ruggeri, G Longo, S Faggiano, E Lipiec, A Pastore, G Dietler
Nature communications 6 (1), 1-9, 2015
2992015
Cholesterol catalyses Aβ42 aggregation through a heterogeneous nucleation pathway in the presence of lipid membranes
J Habchi, S Chia, C Galvagnion, TCT Michaels, MMJ Bellaiche, ...
Nature chemistry 10 (6), 673-683, 2018
2292018
The H50Q mutation enhances α-synuclein aggregation, secretion, and toxicity
O Khalaf, B Fauvet, A Oueslati, I Dikiy, AL Mahul-Mellier, FS Ruggeri, ...
Journal of Biological Chemistry 289 (32), 21856-21876, 2014
2242014
Measurement of intrinsic properties of amyloid fibrils by the peak force QNM method
J Adamcik, C Lara, I Usov, JS Jeong, FS Ruggeri, G Dietler, HA Lashuel, ...
Nanoscale 4 (15), 4426-4429, 2012
2182012
Different soluble aggregates of Aβ42 can give rise to cellular toxicity through different mechanisms
S De, DC Wirthensohn, P Flagmeier, C Hughes, FA Aprile, FS Ruggeri, ...
Nature communications 10 (1), 1541, 2019
1872019
Stabilized tilted-octahedra halide perovskites inhibit local formation of performance-limiting phases
TAS Doherty, S Nagane, DJ Kubicki, YK Jung, DN Johnstone, AN Iqbal, ...
Science 374 (6575), 1598-1605, 2021
1802021
Influence of the β‐sheet content on the mechanical properties of aggregates during amyloid fibrillization
FS Ruggeri, J Adamcik, JS Jeong, HA Lashuel, R Mezzenga, G Dietler
Angewandte Chemie 127 (8), 2492-2496, 2015
1592015
Atomic force microscopy for single molecule characterisation of protein aggregation
FS Ruggeri, T Šneideris, M Vendruscolo, TPJ Knowles
Archives of biochemistry and biophysics 664, 134-148, 2019
1572019
Detecting nanoscale vibrations as signature of life
S Kasas, FS Ruggeri, C Benadiba, C Maillard, P Stupar, H Tournu, ...
Proceedings of the National Academy of Sciences 112 (2), 378-381, 2015
1562015
Trodusquemine enhances Aβ42 aggregation but suppresses its toxicity by displacing oligomers from cell membranes
R Limbocker, S Chia, FS Ruggeri, M Perni, R Cascella, GT Heller, G Meisl, ...
Nature communications 10 (1), 225, 2019
1492019
Nanoscale studies link amyloid maturity with polyglutamine diseases onset
FS Ruggeri, S Vieweg, U Cendrowska, G Longo, A Chiki, HA Lashuel, ...
Scientific reports 6 (1), 31155, 2016
1492016
Biomolecular condensates undergo a generic shear-mediated liquid-to-solid transition
Y Shen, FS Ruggeri, D Vigolo, A Kamada, S Qamar, A Levin, C Iserman, ...
Nature Nanotechnology, 2020
1422020
Nanoplasmonic mid-infrared biosensor for in vitro protein secondary structure detection
D Etezadi, JB Warner IV, FS Ruggeri, G Dietler, HA Lashuel, H Altug
Light: Science & Applications 6 (8), e17029-e17029, 2017
1312017
Small molecule sequestration of amyloid-β as a drug discovery strategy for Alzheimer's disease
GT Heller, FA Aprile, TCT Michaels, R Limbocker, M Perni, FS Ruggeri, ...
Science Advances 6 (45), eabb5924, 2020
1302020
Determination of polypeptide conformation with nanoscale resolution in water
G Ramer, FS Ruggeri, A Levin, TPJ Knowles, A Centrone
ACS nano 12 (7), 6612-6619, 2018
1212018
Single molecule secondary structure determination of proteins through infrared absorption nanospectroscopy
FS Ruggeri, B Mannini, R Schmid, M Vendruscolo, TPJ Knowles
Nature Communications 11 (1), 2945, 2020
1192020
Silk micrococoons for protein stabilisation and molecular encapsulation
U Shimanovich, FS Ruggeri, E De Genst, J Adamcik, TP Barros, D Porter, ...
Nature Communications 8, ncomms15902, 2017
1172017
Small soluble α-synuclein aggregates are the toxic species in Parkinson’s disease
D Emin, YP Zhang, E Lobanova, A Miller, X Li, Z Xia, H Dakin, DI Sideris, ...
Nature communications 13 (1), 5512, 2022
1072022
Identification and nanomechanical characterization of the fundamental single-strand protofilaments of amyloid α-synuclein fibrils
FS Ruggeri, F Benedetti, TPJ Knowles, HA Lashuel, S Sekatskii, G Dietler
Proceedings of the National Academy of Sciences 115 (28), 7230-7235, 2018
1052018
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