FUS phase separation is modulated by a molecular chaperone and methylation of arginine cation-π interactions S Qamar, GZ Wang, SJ Randle, FS Ruggeri, JA Varela, JQ Lin, ... Cell 173 (3), 720-734. e15, 2018 | 831 | 2018 |
Infrared nanospectroscopy characterization of oligomeric and fibrillar aggregates during amyloid formation FS Ruggeri, G Longo, S Faggiano, E Lipiec, A Pastore, G Dietler Nature communications 6 (1), 1-9, 2015 | 299 | 2015 |
Cholesterol catalyses Aβ42 aggregation through a heterogeneous nucleation pathway in the presence of lipid membranes J Habchi, S Chia, C Galvagnion, TCT Michaels, MMJ Bellaiche, ... Nature chemistry 10 (6), 673-683, 2018 | 229 | 2018 |
The H50Q mutation enhances α-synuclein aggregation, secretion, and toxicity O Khalaf, B Fauvet, A Oueslati, I Dikiy, AL Mahul-Mellier, FS Ruggeri, ... Journal of Biological Chemistry 289 (32), 21856-21876, 2014 | 224 | 2014 |
Measurement of intrinsic properties of amyloid fibrils by the peak force QNM method J Adamcik, C Lara, I Usov, JS Jeong, FS Ruggeri, G Dietler, HA Lashuel, ... Nanoscale 4 (15), 4426-4429, 2012 | 218 | 2012 |
Different soluble aggregates of Aβ42 can give rise to cellular toxicity through different mechanisms S De, DC Wirthensohn, P Flagmeier, C Hughes, FA Aprile, FS Ruggeri, ... Nature communications 10 (1), 1541, 2019 | 187 | 2019 |
Stabilized tilted-octahedra halide perovskites inhibit local formation of performance-limiting phases TAS Doherty, S Nagane, DJ Kubicki, YK Jung, DN Johnstone, AN Iqbal, ... Science 374 (6575), 1598-1605, 2021 | 180 | 2021 |
Influence of the β‐sheet content on the mechanical properties of aggregates during amyloid fibrillization FS Ruggeri, J Adamcik, JS Jeong, HA Lashuel, R Mezzenga, G Dietler Angewandte Chemie 127 (8), 2492-2496, 2015 | 159 | 2015 |
Atomic force microscopy for single molecule characterisation of protein aggregation FS Ruggeri, T Šneideris, M Vendruscolo, TPJ Knowles Archives of biochemistry and biophysics 664, 134-148, 2019 | 157 | 2019 |
Detecting nanoscale vibrations as signature of life S Kasas, FS Ruggeri, C Benadiba, C Maillard, P Stupar, H Tournu, ... Proceedings of the National Academy of Sciences 112 (2), 378-381, 2015 | 156 | 2015 |
Trodusquemine enhances Aβ42 aggregation but suppresses its toxicity by displacing oligomers from cell membranes R Limbocker, S Chia, FS Ruggeri, M Perni, R Cascella, GT Heller, G Meisl, ... Nature communications 10 (1), 225, 2019 | 149 | 2019 |
Nanoscale studies link amyloid maturity with polyglutamine diseases onset FS Ruggeri, S Vieweg, U Cendrowska, G Longo, A Chiki, HA Lashuel, ... Scientific reports 6 (1), 31155, 2016 | 149 | 2016 |
Biomolecular condensates undergo a generic shear-mediated liquid-to-solid transition Y Shen, FS Ruggeri, D Vigolo, A Kamada, S Qamar, A Levin, C Iserman, ... Nature Nanotechnology, 2020 | 142 | 2020 |
Nanoplasmonic mid-infrared biosensor for in vitro protein secondary structure detection D Etezadi, JB Warner IV, FS Ruggeri, G Dietler, HA Lashuel, H Altug Light: Science & Applications 6 (8), e17029-e17029, 2017 | 131 | 2017 |
Small molecule sequestration of amyloid-β as a drug discovery strategy for Alzheimer's disease GT Heller, FA Aprile, TCT Michaels, R Limbocker, M Perni, FS Ruggeri, ... Science Advances 6 (45), eabb5924, 2020 | 130 | 2020 |
Determination of polypeptide conformation with nanoscale resolution in water G Ramer, FS Ruggeri, A Levin, TPJ Knowles, A Centrone ACS nano 12 (7), 6612-6619, 2018 | 121 | 2018 |
Single molecule secondary structure determination of proteins through infrared absorption nanospectroscopy FS Ruggeri, B Mannini, R Schmid, M Vendruscolo, TPJ Knowles Nature Communications 11 (1), 2945, 2020 | 119 | 2020 |
Silk micrococoons for protein stabilisation and molecular encapsulation U Shimanovich, FS Ruggeri, E De Genst, J Adamcik, TP Barros, D Porter, ... Nature Communications 8, ncomms15902, 2017 | 117 | 2017 |
Small soluble α-synuclein aggregates are the toxic species in Parkinson’s disease D Emin, YP Zhang, E Lobanova, A Miller, X Li, Z Xia, H Dakin, DI Sideris, ... Nature communications 13 (1), 5512, 2022 | 107 | 2022 |
Identification and nanomechanical characterization of the fundamental single-strand protofilaments of amyloid α-synuclein fibrils FS Ruggeri, F Benedetti, TPJ Knowles, HA Lashuel, S Sekatskii, G Dietler Proceedings of the National Academy of Sciences 115 (28), 7230-7235, 2018 | 105 | 2018 |