Reuben S Harris
Reuben S Harris
Professor of Biochemistry and Structural Biology, HHMI and University of Texas Health San Antonio
Verified email at - Homepage
Cited by
Cited by
DNA deamination mediates innate immunity to retroviral infection
RS Harris, KN Bishop, AM Sheehy, HM Craig, SK Petersen-Mahrt, IN Watt, ...
Cell 113 (6), 803-809, 2003
AID mutates E. coli suggesting a DNA deamination mechanism for antibody diversification
SK Petersen-Mahrt, RS Harris, MS Neuberger
Nature 418 (6893), 99-104, 2002
APOBEC3B is an enzymatic source of mutation in breast cancer
MB Burns, L Lackey, MA Carpenter, A Rathore, AM Land, B Leonard, ...
Nature 494 (7437), 366-370, 2013
Retroviral restriction by APOBEC proteins
RS Harris, MT Liddament
Nature Reviews Immunology 4 (11), 868-877, 2004
Evidence for APOBEC3B mutagenesis in multiple human cancers
MB Burns, NA Temiz, RS Harris
Nature genetics 45 (9), 977-983, 2013
RNA editing enzyme APOBEC1 and some of its homologs can act as DNA mutators
RS Harris, SK Petersen-Mahrt, MS Neuberger
Molecular cell 10 (5), 1247-1253, 2002
The Vif protein of HIV triggers degradation of the human antiretroviral DNA deaminase APOBEC3G
SG Conticello, RS Harris, MS Neuberger
Current Biology 13 (22), 2009-2013, 2003
APOBEC3F properties and hypermutation preferences indicate activity against HIV-1 in vivo
MT Liddament, WL Brown, AJ Schumacher, RS Harris
Current Biology 14 (15), 1385-1391, 2004
APOBECs and virus restriction
RS Harris, JP Dudley
Virology 479, 131-145, 2015
APOBEC enzymes: mutagenic fuel for cancer evolution and heterogeneity
C Swanton, N McGranahan, GJ Starrett, RS Harris
Cancer discovery 5 (7), 704-712, 2015
Vif hijacks CBF-β to degrade APOBEC3G and promote HIV-1 infection
S Jäger, DY Kim, JF Hultquist, K Shindo, RS LaRue, E Kwon, M Li, ...
Nature 481 (7381), 371-375, 2012
Quantitative profiling of the full APOBEC3 mRNA repertoire in lymphocytes and tissues: implications for HIV-1 restriction
EW Refsland, MD Stenglein, K Shindo, JS Albin, WL Brown, RS Harris
Nucleic acids research 38 (13), 4274-4284, 2010
Human and rhesus APOBEC3D, APOBEC3F, APOBEC3G, and APOBEC3H demonstrate a conserved capacity to restrict Vif-deficient HIV-1
JF Hultquist, JA Lengyel, EW Refsland, RS LaRue, L Lackey, WL Brown, ...
Journal of virology 85 (21), 11220-11234, 2011
Comparison of the differential context-dependence of DNA deamination by APOBEC enzymes: correlation with mutation spectra in vivo
RCL Beale, SK Petersen-Mahrt, IN Watt, RS Harris, C Rada, ...
Journal of molecular biology 337 (3), 585-596, 2004
APOBEC3 proteins mediate the clearance of foreign DNA from human cells
MD Stenglein, MB Burns, M Li, J Lengyel, RS Harris
Nature structural & molecular biology 17 (2), 222-229, 2010
The restriction factors of human immunodeficiency virus
RS Harris, JF Hultquist, DT Evans
Journal of Biological Chemistry 287 (49), 40875-40883, 2012
The SOS response regulates adaptive mutation
GJ McKenzie, RS Harris, PL Lee, SM Rosenberg
Proceedings of the National Academy of Sciences 97 (12), 6646-6651, 2000
Human immunodeficiency virus type 1 cDNAs produced in the presence of APOBEC3G exhibit defects in plus-strand DNA transfer and integration
JL Mbisa, R Barr, JA Thomas, N Vandegraaff, IJ Dorweiler, ...
Journal of virology 81 (13), 7099-7110, 2007
APOBEC3B and APOBEC3F inhibit L1 retrotransposition by a DNA deamination-independent mechanism
MD Stenglein, RS Harris
Journal of Biological Chemistry 281 (25), 16837-16841, 2006
Recombination in adaptive mutation
RS Harris, S Longerich, SM Rosenberg
Science 264 (5156), 258-260, 1994
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