Birgit Obermeier
Birgit Obermeier
Voyager Therapeutics
Patvirtintas el. paštas
Development, maintenance and disruption of the blood-brain barrier
B Obermeier, R Daneman, RM Ransohoff
Nature medicine 19 (12), 1584-1596, 2013
Matching of oligoclonal immunoglobulin transcriptomes and proteomes of cerebrospinal fluid in multiple sclerosis
B Obermeier, R Mentele, J Malotka, J Kellermann, T Kümpfel, H Wekerle, ...
Nature medicine 14 (6), 688-693, 2008
A perfused human blood–brain barrier on-a-chip for high-throughput assessment of barrier function and antibody transport
NR Wevers, DG Kasi, T Gray, KJ Wilschut, B Smith, R Van Vught, ...
Fluids and Barriers of the CNS 15 (1), 1-12, 2018
The blood-brain barrier
B Obermeier, A Verma, RM Ransohoff
Handb. Clin. Neurol. 133, 39-59, 2016
Distinct oligoclonal band antibodies in multiple sclerosis recognize ubiquitous self-proteins
SM Brändle, B Obermeier, M Senel, J Bruder, R Mentele, M Khademi, ...
Proceedings of the National Academy of Sciences 113 (28), 7864-7869, 2016
Effects of neuromyelitis optica–IgG at the blood–brain barrier in vitro
Y Takeshita, B Obermeier, AC Cotleur, SF Spampinato, F Shimizu, ...
Neurology® Neuroimmunology & Neuroinflammation 4 (1), 2017
Related B cell clones that populate the CSF and CNS of patients with multiple sclerosis produce CSF immunoglobulin
B Obermeier, L Lovato, R Mentele, W Brück, I Forne, A Imhof, F Lottspeich, ...
Journal of neuroimmunology 233 (1-2), 245-248, 2011
Glucose-regulated protein 78 autoantibody associates with blood-brain barrier disruption in neuromyelitis optica
F Shimizu, KL Schaller, GP Owens, AC Cotleur, D Kellner, Y Takeshita, ...
Science translational medicine 9 (397), eaai9111, 2017
Design and validation of a human brain endothelial microvessel-on-a-chip open microfluidic model enabling advanced optical imaging
MM Salman, G Marsh, I Küsters, M Delincé, GD Caprio, S Upadhyayula, ...
Front. Bioeng. Biotechnol 8, 1077, 2020
Intrathecal somatic hypermutation of IgM in multiple sclerosis and neuroinflammation
E Beltrán, B Obermeier, M Moser, F Coret, M Simó-Castelló, I Boscá, ...
Brain 137 (10), 2703-2714, 2014
Sphingosine 1 phosphate at the blood brain barrier: can the modulation of s1p receptor 1 influence the response of endothelial cells and astrocytes to inflammatory stimuli?
SF Spampinato, B Obermeier, A Cotleur, A Love, Y Takeshita, Y Sano, ...
PloS one 10 (7), e0133392, 2015
An in vitro blood–brain barrier model combining shear stress and endothelial cell/astrocyte co-culture
Y Takeshita, B Obermeier, A Cotleur, Y Sano, T Kanda, RM Ransohoff
Journal of neuroscience methods 232, 165-172, 2014
Target specificity of an autoreactive pathogenic human γδ-T cell receptor in myositis
J Bruder, K Siewert, B Obermeier, J Malotka, P Scheinert, J Kellermann, ...
Journal of Biological Chemistry 287 (25), 20986-20995, 2012
An In Vitro Model of the Blood–Brain Barrier to Study Alzheimer’s Disease: The Role of β-Amyloid and Its Influence on PBMC Infiltration
SF Spampinato, Y Takeshita, B Obermeier
The Blood-Brain Barrier: Methods and Protocols, 333-352, 2022
Analysis of patient-specific immunoglobulin proteomes and transcriptomes by PCR cloning and mass spectrometry
B Obermeier, R Mentele, J Malotka, K Dornmair
Molecular characterization of paired immunoglobulin heavy and light chains of clonally expanded antibodies in the presence of a strong polyclonal background
B Obermeier, E Beltrán, R Hohlfeld, K Dornmair
Effects of Neuromyelitis Optica (NMO)-IgG for leukocyte transmigration at the Blood-Brain Barrier (S46. 003)
Y Takeshita, B Obermeier, A Cotleur, F Shimizu, S Spampinato, T Kryzer, ...
Neurology 84 (14 Supplement), 2015
Modulation of S1P receptors at the Blood Brain Barrier: do astrocytes play an essential role?
S Spampinato, B Obermeier, A Cotleur, A Love, Y Takeshita, R Ransohoff
Glia, ---, 2015
Novel insights into cell-cell interactions at the blood-brain barrier revealed by a fully-human flow-based in vitro model
B Obermeier, BL Benson, H Lu, G Kidd, S Spampinato, Y Takeshita, ...
Journal of Neuroimmunology 275 (1), 32, 2014
Characterization of individual IgM oligoclonal band antibodies from the cerebrospinal fluid (CSF) of multiple sclerosis patients to identify their antigens
E Beltran, B Obermeier, F Coret, M Simo-Castello, FC Perez-Miralles, ...
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Straipsniai 1–20