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Andrew Macintyre
Andrew Macintyre
Verified email at duke.edu
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Year
Cutting edge: distinct glycolytic and lipid oxidative metabolic programs are essential for effector and regulatory CD4+ T cell subsets
RD Michalek, VA Gerriets, SR Jacobs, AN Macintyre, NJ MacIver, ...
The Journal of immunology 186 (6), 3299-3303, 2011
20512011
Phosphoenolpyruvate is a metabolic checkpoint of anti-tumor T cell responses
PC Ho, JD Bihuniak, AN Macintyre, M Staron, X Liu, R Amezquita, ...
Cell 162 (6), 1217-1228, 2015
12332015
The glucose transporter Glut1 is selectively essential for CD4 T cell activation and effector function
AN Macintyre, VA Gerriets, AG Nichols, RD Michalek, MC Rudolph, ...
Cell metabolism 20 (1), 61-72, 2014
10742014
Metabolic reprogramming of macrophages: glucose transporter 1 (GLUT1)-mediated glucose metabolism drives a proinflammatory phenotype
AJ Freemerman, AR Johnson, GN Sacks, JJ Milner, EL Kirk, MA Troester, ...
Journal of Biological Chemistry 289 (11), 7884-7896, 2014
8602014
Metabolic programming and PDHK1 control CD4+ T cell subsets and inflammation
VA Gerriets, RJ Kishton, AG Nichols, AN Macintyre, M Inoue, O Ilkayeva, ...
The Journal of clinical investigation 125 (1), 194-207, 2015
6612015
Multi-omics analyses of radiation survivors identify radioprotective microbes and metabolites
H Guo, WC Chou, Y Lai, K Liang, JW Tam, WJ Brickey, L Chen, ...
Science 370 (6516), eaay9097, 2020
3032020
Protein kinase B controls transcriptional programs that direct cytotoxic T cell fate but is dispensable for T cell metabolism
AN Macintyre, D Finlay, G Preston, LV Sinclair, CM Waugh, P Tamas, ...
Immunity 34 (2), 224-236, 2011
2932011
In vitro and in vivo functions of SARS-CoV-2 infection-enhancing and neutralizing antibodies
D Li, RJ Edwards, K Manne, DR Martinez, A Schäfer, SM Alam, K Wiehe, ...
Cell 184 (16), 4203-4219. e32, 2021
2332021
AMPK is essential to balance glycolysis and mitochondrial metabolism to control T-ALL cell stress and survival
RJ Kishton, CE Barnes, AG Nichols, S Cohen, VA Gerriets, PJ Siska, ...
Cell metabolism 23 (4), 649-662, 2016
2242016
Compartmentalization of cAMP-dependent signaling by phosphodiesterase-4D is involved in the regulation of vasopressin-mediated water reabsorption in renal principal cells
E Stefan, B Wiesner, GS Baillie, R Mollajew, V Henn, D Lorenz, J Furkert, ...
Journal of the American Society of Nephrology 18 (1), 199-212, 2007
1692007
Metabolic reprogramming towards aerobic glycolysis correlates with greater proliferative ability and resistance to metabolic inhibition in CD8 versus CD4 T cells
Y Cao, JC Rathmell, AN Macintyre
PloS one 9 (8), e104104, 2014
1682014
Antigen receptor control of methionine metabolism in T cells
LV Sinclair, AJM Howden, A Brenes, L Spinelli, JL Hukelmann, ...
Elife 8, e44210, 2019
1512019
Autophagy is essential to suppress cell stress and to allow BCR-Abl-mediated leukemogenesis
BJ Altman, SR Jacobs, EF Mason, RD Michalek, AN MacIntyre, JL Coloff, ...
Oncogene 30 (16), 1855-1867, 2011
1512011
Akt-dependent glucose metabolism promotes Mcl-1 synthesis to maintain cell survival and resistance to Bcl-2 inhibition
JL Coloff, AN Macintyre, AG Nichols, T Liu, CA Gallo, DR Plas, ...
Cancer research 71 (15), 5204-5213, 2011
1392011
Activated lymphocytes as a metabolic model for carcinogenesis
AN Macintyre, JC Rathmell
Cancer & metabolism 1, 1-12, 2013
1182013
LKB1 is essential for the proliferation of T‐cell progenitors and mature peripheral T cells
P Tamás, A Macintyre, D Finlay, R Clarke, C Feijoo‐Carnero, A Ashworth, ...
European journal of immunology 40 (1), 242-253, 2010
992010
Glucose transporter 1-mediated glucose uptake is limiting for B-cell acute lymphoblastic leukemia anabolic metabolism and resistance to apoptosis
T Liu, RJ Kishton, AN Macintyre, VA Gerriets, H Xiang, X Liu, ED Abel, ...
Cell death & disease 5 (10), e1470-e1470, 2014
812014
Acetalated dextran microparticles for codelivery of STING and TLR7/8 agonists
MA Collier, RD Junkins, MD Gallovic, BM Johnson, MM Johnson, ...
Molecular pharmaceutics 15 (11), 4933-4946, 2018
762018
The serogroup B meningococcal outer membrane vesicle-based vaccine 4CMenB induces cross-species protection against Neisseria gonorrhoeae
I Leduc, KL Connolly, A Begum, K Underwood, S Darnell, WM Shafer, ...
PLoS pathogens 16 (12), e1008602, 2020
612020
The functions of SARS-CoV-2 neutralizing and infection-enhancing antibodies in vitro and in mice and nonhuman primates
D Li, RJ Edwards, K Manne, DR Martinez, A Schäfer, SM Alam, K Wiehe, ...
BioRxiv, 2020.12. 31.424729, 2021
592021
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