Ramesh Neelamegam
Ramesh Neelamegam
Unknown affiliation
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Late Stage Benzylic C–H Fluorination with [18F]Fluoride for PET Imaging
X Huang, W Liu, H Ren, R Neelamegam, JM Hooker, JT Groves
Journal of the American Chemical Society 136 (19), 6842-6845, 2014
Brain-penetrant LSD1 inhibitors can block memory consolidation
R Neelamegam, EL Ricq, M Malvaez, D Patnaik, S Norton, SM Carlin, ...
ACS chemical neuroscience 3 (2), 120-128, 2012
Autoradiography validation of novel tau PET tracer [F-18]-MK-6240 on human postmortem brain tissue
C Aguero, M Dhaynaut, MD Normandin, AC Amaral, NJ Guehl, ...
Acta neuropathologica communications 7 (1), 1-15, 2019
Synthesis and Imaging Validation of [18F]MDL100907 Enabled by Ni-Mediated Fluorination
H Ren, HY Wey, M Strebl, R Neelamegam, T Ritter, JM Hooker
ACS Chemical Neuroscience 5 (7), 611-615, 2014
Imaging Evaluation of 5HT2C Agonists, [11C]WAY-163909 and [11C]Vabicaserin, Formed by Pictet–Spengler Cyclization
R Neelamegam, T Hellenbrand, FA Schroeder, C Wang, JM Hooker
Journal of Medicinal Chemistry 57 (4), 1488-1494, 2014
A simple iodination protocol via in situ generated ICl using NaI/FeCl3
AK Mohanakrishnan, C Prakash, N Ramesh
Tetrahedron 62 (14), 3242-3247, 2006
PET imaging demonstrates histone deacetylase target engagement and clarifies brain penetrance of known and novel small molecule inhibitors in rat
FA Schroeder, C Wang, GC Van de Bittner, R Neelamegam, ...
ACS chemical neuroscience 5 (10), 1055-1062, 2014
Design, synthesis, and evaluation of hydroxamic acid-based molecular probes for in vivo imaging of histone deacetylase (HDAC) in brain
C Wang, TE Eessalu, VN Barth, CH Mitch, FF Wagner, Y Hong, ...
American journal of nuclear medicine and molecular imaging 4 (1), 29, 2014
Development of a fluorinated class-I HDAC radiotracer reveals key chemical determinants of brain penetrance
MG Strebl, C Wang, FA Schroeder, MS Placzek, HY Wey, ...
ACS chemical neuroscience 7 (5), 528-533, 2016
Synthesis of di-, tri-, and tetra-substituted carbazole analogs involving annulation methodology
N Ramesh, GG Rajeshwaran, AK Mohanakrishnan
Tetrahedron 65 (18), 3592-3602, 2009
cGMP production of the radiopharmaceutical [18F] MK‐6240 for PET imaging of human neurofibrillary tangles
TL Collier, DL Yokell, E Livni, PA Rice, S Celen, K Serdons, ...
Journal of Labelled Compounds and Radiopharmaceuticals 60 (5), 263-269, 2017
Discrepancies in kappa opioid agonist binding revealed through PET imaging
MS Placzek, FA Schroeder, T Che, HY Wey, R Neelamegam, C Wang, ...
ACS Chemical Neuroscience 10 (1), 384-395, 2018
An Efficient and Practical Radiosynthesis of [11C]Temozolomide
CK Moseley, SM Carlin, R Neelamegam, JM Hooker
Organic letters 14 (23), 5872-5875, 2012
Radiosynthesis and evaluation of [11C] EMPA as a potential PET tracer for orexin 2 receptors
C Wang, CK Moseley, SM Carlin, CM Wilson, R Neelamegam, JM Hooker
Bioorganic & medicinal chemistry letters 23 (11), 3389-3392, 2013
Synthesis and Evaluation of Methylated Arylazepine Compounds for PET Imaging of 5-HT2c Receptors
ML Granda, SM Carlin, CK Moseley, R Neelamegam, JB Mandeville, ...
ACS Chemical Neuroscience 4 (2), 261-265, 2013
Evaluation of the potassium channel tracer [18F]3F4AP in rhesus macaques
NJ Guehl, KM Ramos-Torres, C Linnman, SH Moon, M Dhaynaut, ...
Journal of Cerebral Blood Flow & Metabolism 41 (7), 1721-1733, 2021
Novel radioligands for imaging sigma-1 receptor in brain using positron emission tomography (PET)
Y Lan, P Bai, Z Chen, R Neelamegam, MS Placzek, H Wang, SA Fiedler, ...
Acta Pharmaceutica Sinica B 9 (6), 1204-1215, 2019
Ethyl 2-bromomethyl-1-phenylsulfonyl-1H-indole-3-carboxylate
G Chakkaravarthi, N Ramesh, AK Mohanakrishnan, V Manivannan
Acta Crystallographica Section E: Structure Reports Online 63 (8), o3564-o3564, 2007
An efficient preparation of 1-phenylsulfonylindolyl methyl sulfoxides using KF/m-CPBA
AK Mohanakrishnan, N Ramesh
Tetrahedron letters 46 (24), 4231-4233, 2005
In vivo imaging of mGlu5 receptor expression in humans with Fragile X Syndrome towards development of a potential biomarker
M Mody, Y Petibon, P Han, D Kuruppu, C Ma, D Yokell, R Neelamegam, ...
Scientific reports 11 (1), 15897, 2021
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