Rosiglitazone abrogates bleomycin-induced scleroderma and blocks profibrotic responses through peroxisome proliferator-activated receptor-γ M Wu, DS Melichian, E Chang, M Warner-Blankenship, AK Ghosh, ... The American journal of pathology 174 (2), 519-533, 2009 | 260 | 2009 |
Hypoxia-induced alveolar epithelial-mesenchymal transition requires mitochondrial ROS and hypoxia-inducible factor 1 G Zhou, LA Dada, M Wu, A Kelly, H Trejo, Q Zhou, J Varga, JI Sznajder American Journal of Physiology-Lung Cellular and Molecular Physiology 297 (6 …, 2009 | 257 | 2009 |
Tenascin-C drives persistence of organ fibrosis S Bhattacharyya, W Wang, L Morales-Nebreda, G Feng, M Wu, X Zhou, ... Nature communications 7 (1), 11703, 2016 | 247 | 2016 |
PPARγ downregulation by TGFß in fibroblast and impaired expression and function in systemic sclerosis: a novel mechanism for progressive fibrogenesis J Wei, AK Ghosh, JL Sargent, K Komura, M Wu, QQ Huang, M Jain, ... PloS one 5 (11), e13778, 2010 | 209 | 2010 |
Cadherin-11 contributes to pulmonary fibrosis: potential role in TGF-β production and epithelial to mesenchymal transition DJ Schneider, M Wu, TT Le, SH Cho, MB Brenner, MR Blackburn, ... The FASEB Journal 26 (2), 503, 2012 | 163 | 2012 |
Dissecting the heterogeneity of skin gene expression patterns in systemic sclerosis S Assassi, WR Swindell, M Wu, FD Tan, D Khanna, DE Furst, DP Tashkin, ... Arthritis & rheumatology 67 (11), 3016-3026, 2015 | 155 | 2015 |
Early growth response transcription factors: key mediators of fibrosis and novel targets for anti-fibrotic therapy S Bhattacharyya, M Wu, F Fang, W Tourtellotte, C Feghali-Bostwick, ... Matrix Biology 30 (4), 235-242, 2011 | 141 | 2011 |
Essential roles for early growth response transcription factor Egr-1 in tissue fibrosis and wound healing M Wu, DS Melichian, M De La Garza, K Gruner, S Bhattacharyya, L Barr, ... The American journal of pathology 175 (3), 1041-1055, 2009 | 130 | 2009 |
Global skin gene expression analysis of early diffuse cutaneous systemic sclerosis shows a prominent innate and adaptive inflammatory profile B Skaug, D Khanna, WR Swindell, ME Hinchcliff, TM Frech, VD Steen, ... Annals of the rheumatic diseases 79 (3), 379-386, 2020 | 124 | 2020 |
The role of type 1 interferon in systemic sclerosis M Wu, S Assassi Frontiers in immunology 4, 59278, 2013 | 119 | 2013 |
Smad-independent transforming growth factor-β regulation of early growth response-1 and sustained expression in fibrosis: Implications for scleroderma S Bhattacharyya, SJ Chen, M Wu, M Warner-Blankenship, H Ning, ... The American journal of pathology 173 (4), 1085-1099, 2008 | 115 | 2008 |
Correlation of interferon‐inducible chemokine plasma levels with disease severity in systemic sclerosis X Liu, MD Mayes, FK Tan, M Wu, JD Reveille, BE Harper, HT Draeger, ... Arthritis & Rheumatism 65 (1), 226-235, 2013 | 103 | 2013 |
Toll-like receptor 3 upregulation by type I interferon in healthy and scleroderma dermal fibroblasts SK Agarwal, M Wu, CK Livingston, DH Parks, MD Mayes, FC Arnett, ... Arthritis research & therapy 13, 1-10, 2011 | 103 | 2011 |
The early growth response gene Egr2 (Alias Krox20) is a novel transcriptional target of transforming growth factor-β that is up-regulated in systemic sclerosis and mediates … F Fang, K Ooka, S Bhattachyya, J Wei, M Wu, P Du, S Lin, F Del Galdo, ... The American journal of pathology 178 (5), 2077-2090, 2011 | 99 | 2011 |
Proteasomal inhibition after injury prevents fibrosis by modulating TGF-β1 signalling GM Mutlu, GRS Budinger, M Wu, AP Lam, A Zirk, S Rivera, D Urich, ... Thorax 67 (2), 139-146, 2012 | 98 | 2012 |
Osteopontin in systemic sclerosis and its role in dermal fibrosis M Wu, DJ Schneider, MD Mayes, S Assassi, FC Arnett, FK Tan, ... Journal of Investigative Dermatology 132 (6), 1605-1614, 2012 | 86 | 2012 |
Identification of cadherin 11 as a mediator of dermal fibrosis and possible role in systemic sclerosis M Wu, M Pedroza, R Lafyatis, AT George, MD Mayes, S Assassi, FK Tan, ... Arthritis & rheumatology 66 (4), 1010-1021, 2014 | 83 | 2014 |
MAP-kinase activity necessary for TGFβ1-stimulated mesangial cell type I collagen expression requires adhesion-dependent phosphorylation of FAK tyrosine 397 T Hayashida, MH Wu, A Pierce, AC Poncelet, J Varga, HW Schnaper Journal of cell science 120 (23), 4230-4240, 2007 | 82 | 2007 |
Increased bleomycin-induced skin fibrosis in mice lacking the Th1-specific transcription factor T-bet G Lakos, D Melichian, M Wu, J Varga Pathobiology 73 (5), 224-237, 2007 | 78 | 2007 |
CCL2 in the Circulation Predicts Long‐Term Progression of Interstitial Lung Disease in Patients With Early Systemic Sclerosis: Data From Two Independent Cohorts M Wu, M Baron, C Pedroza, GA Salazar, J Ying, J Charles, SK Agarwal, ... Arthritis & Rheumatology 69 (9), 1871-1878, 2017 | 77 | 2017 |