Daniel Rotroff
Daniel Rotroff
Director, Center for Quantitative Metabolic Research, Cleveland Clinic
Verified email at - Homepage
Cited by
Cited by
In Vitro Screening of Environmental Chemicals for Targeted Testing Prioritization: The ToxCast Project
RS Judson, KA Houck, RJ Kavlock, TB Knudsen, MT Martin, ...
Environmental health perspectives 118 (4), 485-492, 2010
Update on EPA’s ToxCast program: providing high throughput decision support tools for chemical risk management
R Kavlock, K Chandler, K Houck, S Hunter, R Judson, N Kleinstreuer, ...
Chemical research in toxicology 25 (7), 1287-1302, 2012
Integration of dosimetry, exposure, and high-throughput screening data in chemical toxicity assessment
BA Wetmore, JF Wambaugh, SS Ferguson, MA Sochaski, DM Rotroff, ...
Toxicological Sciences 125 (1), 157-174, 2012
Altered bile acid profile associates with cognitive impairment in Alzheimer's disease—an emerging role for gut microbiome
S MahmoudianDehkordi, M Arnold, K Nho, S Ahmad, W Jia, G Xie, ...
Alzheimer's & Dementia 15 (1), 76-92, 2019
Metabolic network failures in Alzheimer's disease: a biochemical road map
JB Toledo, M Arnold, G Kastenmüller, R Chang, RA Baillie, X Han, ...
Alzheimer's & Dementia 13 (9), 965-984, 2017
Incorporating Human Dosimetry and Exposure into High-Throughput In Vitro Toxicity Screening
DM Rotroff, BA Wetmore, DJ Dix, SS Ferguson, HJ Clewell, KA Houck, ...
Toxicological Sciences 117 (2), 348-358, 2010
Integrated Model of Chemical Perturbations of a Biological Pathway Using 18 In Vitro High-Throughput Screening Assays for the Estrogen Receptor
RS Judson, FM Magpantay, V Chickarmane, C Haskell, N Tania, J Taylor, ...
Toxicological Sciences 148 (1), 137-154, 2015
Community assessment to advance computational prediction of cancer drug combinations in a pharmacogenomic screen
MP Menden, D Wang, MJ Mason, B Szalai, KC Bulusu, Y Guan, T Yu, ...
Nature communications 10 (1), 2674, 2019
Editor's Highlight: Analysis of the Effects of Cell Stress and Cytotoxicity on In Vitro Assay Activity Across a Diverse Chemical and Assay Space
R Judson, K Houck, M Martin, AM Richard, TB Knudsen, I Shah, S Little, ...
Toxicological Sciences 152 (2), 323-339, 2016
Impact of environmental chemicals on key transcription regulators and correlation to toxicity end points within EPA’s ToxCast program
MT Martin, DJ Dix, RS Judson, RJ Kavlock, DM Reif, AM Richard, ...
Chemical research in toxicology 23 (3), 578-590, 2010
Analysis of eight oil spill dispersants using rapid, in vitro tests for endocrine and other biological activity
RS Judson, MT Martin, DM Reif, KA Houck, TB Knudsen, DM Rotroff, ...
Environmental science & technology 44 (15), 5979-5985, 2010
Variation in the glucose transporter gene SLC2A2 is associated with glycemic response to metformin
K Zhou, SW Yee, EL Seiser, N Van Leeuwen, R Tavendale, AJ Bennett, ...
Nature genetics 48 (9), 1055-1059, 2016
Profiling of the Tox21 10K compound library for agonists and antagonists of the estrogen receptor alpha signaling pathway
R Huang, S Sakamuru, MT Martin, DM Reif, RS Judson, KA Houck, ...
Scientific reports 4 (1), 5664, 2014
Using in Vitro High Throughput Screening Assays to Identify Potential Endocrine-Disrupting Chemicals
DM Rotroff, DJ Dix, KA Houck, TB Knudsen, MT Martin, KW McLaurin, ...
Environmental Health Perspectives 121 (1), 7-14, 2013
Profiling the reproductive toxicity of chemicals from multigeneration studies in the toxicity reference database
MT Martin, E Mendez, DG Corum, RS Judson, RJ Kavlock, DM Rotroff, ...
Toxicological Sciences 110 (1), 181-190, 2009
Gene set analysis methods: a systematic comparison
R Mathur, D Rotroff, J Ma, A Shojaie, A Motsinger-Reif
BioData mining 11 (1), 1-19, 2018
Development of a thyroperoxidase inhibition assay for high-throughput screening
KB Paul, JM Hedge, DM Rotroff, MW Hornung, KM Crofton, SO Simmons
Chemical research in toxicology 27 (3), 387-399, 2014
Metabolomic signatures of drug response phenotypes for ketamine and esketamine in subjects with refractory major depressive disorder: new mechanistic insights for rapid acting …
DM Rotroff, DG Corum, A Motsinger-Reif, O Fiehn, N Bottrel, WC Drevets, ...
Translational psychiatry 6 (9), e894-e894, 2016
Predictive Endocrine Testing in the 21st Century Using in Vitro Assays of Estrogen Receptor Signaling Responses
DM Rotroff, MT Martin, DJ Dix, DL Filer, KA Houck, TB Knudsen, NS Sipes, ...
Environmental science & technology 48 (15), 8706-8716, 2014
Binary classification of a large collection of environmental chemicals from estrogen receptor assays by quantitative structure–activity relationship and machine learning methods
Q Zang, DM Rotroff, RS Judson
Journal of chemical information and modeling 53 (12), 3244-3261, 2013
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