| Polyplex micelles with phenylboronate/gluconamide cross-linking in the core exerting promoted gene transfection through spatiotemporal responsivity to intracellular pH and ATP … N Yoshinaga, T Ishii, M Naito, T Endo, S Uchida, H Cabral, K Osada, ... Journal of the American Chemical Society 139 (51), 18567-18575, 2017 | 80 | 2017 |
| Precise tuning of disulphide crosslinking in mRNA polyplex micelles for optimising extracellular and intracellular nuclease tolerability A Dirisala, S Uchida, TA Tockary, N Yoshinaga, J Li, S Osawa, L Gorantla, ... Journal of Drug Targeting 27 (5-6), 670-680, 2019 | 63 | 2019 |
| Induced packaging of mRNA into polyplex micelles by regulated hybridization with a small number of cholesteryl RNA oligonucleotides directed enhanced in vivo transfection N Yoshinaga, S Uchida, M Naito, K Osada, H Cabral, K Kataoka Biomaterials 197, 255-267, 2019 | 53 | 2019 |
| Systemic Delivery of Folate-PEG siRNA Lipopolyplexes with Enhanced Intracellular Stability for In Vivo Gene Silencing in Leukemia DJ Lee, E Kessel, T Lehto, X Liu, N Yoshinaga, K Padari, YC Chen, ... Bioconjugate chemistry 28 (9), 2393-2409, 2017 | 53 | 2017 |
| Designing immunostimulatory double stranded messenger RNA with maintained translational activity through hybridization with poly A sequences for effective vaccination S Uchida, N Yoshinaga, K Yanagihara, E Yuba, K Kataoka, K Itaka Biomaterials 150, 162-170, 2018 | 46 | 2018 |
| Bundling mRNA Strands to Prepare Nano‐Assemblies with Enhanced Stability Towards RNase for In Vivo Delivery N Yoshinaga, E Cho, K Koji, Y Mochida, M Naito, K Osada, K Kataoka, ... Angewandte Chemie 131 (33), 11482-11485, 2019 | 44 | 2019 |
| mRNA loading into ATP-responsive polyplex micelles with optimal density of phenylboronate ester crosslinking to balance robustness in the biological milieu and intracellular … N Yoshinaga, S Uchida, A Dirisala, M Naito, K Osada, H Cabral, ... Journal of controlled release 330, 317-328, 2021 | 40 | 2021 |
| Enhanced intracellular delivery of siRNA by controlling ATP‐responsivity of phenylboronic acid‐functionalized polyion complex micelles M Naito, N Yoshinaga, T Ishii, A Matsumoto, Y Miyahara, K Miyata, ... Macromolecular Bioscience 18 (1), 1700357, 2018 | 40 | 2018 |
| Bundling of mRNA strands inside polyion complexes improves mRNA delivery efficiency in vitro and in vivo K Koji, N Yoshinaga, Y Mochida, T Hong, T Miyazaki, K Kataoka, K Osada, ... Biomaterials 261, 120332, 2020 | 38 | 2020 |
| PEG-OligoRNA hybridization of mRNA for developing sterically stable lipid nanoparticles toward in vivo administration S Kurimoto, N Yoshinaga, K Igarashi, Y Matsumoto, H Cabral, S Uchida Molecules 24 (7), 1303, 2019 | 29 | 2019 |
| Rational designs at the forefront of mitochondria-targeted gene delivery: recent progress and future perspectives N Yoshinaga, K Numata ACS Biomaterials Science & Engineering 8 (2), 348-359, 2022 | 22 | 2022 |
| Bridging mRNA and polycation using RNA oligonucleotide derivatives improves the robustness of polyplex micelles for efficient mRNA delivery N Yoshinaga, S Uchida, A Dirisala, M Naito, K Koji, K Osada, H Cabral, ... Advanced Healthcare Materials 11 (9), 2102016, 2022 | 16 | 2022 |
| PEGylation of mRNA by hybridization of complementary PEG-RNA oligonucleotides stabilizes mRNA without using cationic materials N Yoshinaga, M Naito, Y Tachihara, E Boonstra, K Osada, H Cabral, ... Pharmaceutics 13 (6), 800, 2021 | 16 | 2021 |
| Comb-structured mRNA vaccine tethered with short double-stranded RNA adjuvants maximizes cellular immunity for cancer treatment TA Tockary, S Abbasi, M Matsui-Masai, A Hayashi, N Yoshinaga, ... Proceedings of the National Academy of Sciences 120 (29), e2214320120, 2023 | 14 | 2023 |
| Phenylboronic acid-functionalized polyplexes tailored to oral CRISPR delivery N Yoshinaga, JK Zhou, C Xu, CH Quek, Y Zhu, D Tang, LY Hung, ... Nano letters 23 (3), 757-764, 2023 | 10 | 2023 |
| Effect of oligomers derived from biodegradable polyesters on eco-and neurotoxicity N Yoshinaga, A Tateishi, Y Kobayashi, T Kubo, H Miyakawa, K Satoh, ... Biomacromolecules 24 (6), 2721-2729, 2023 | 5 | 2023 |
| MRNA functionalization method S Uchida, K Itaka, K Kataoka, N Yoshinaga US Patent 11,364,259, 2022 | 5 | 2022 |
| Multilayered polyion complexes with dissolvable silica layer covered by controlling densities of cRGD-conjugated PEG chains for cancer-targeted siRNA delivery M Naito, R Azuma, H Takemoto, M Hori, N Yoshinaga, S Osawa, ... Journal of Biomaterials Science, Polymer Edition 28 (10-12), 1109-1123, 2017 | 5 | 2017 |
| mRNA structuring for stabilizing mRNA nanocarriers and improving their delivery efficiency S Uchida, K Koji, N Yoshinaga, Y Mochida, T Hong, H Cabral Materials Proceedings 4 (1), 82, 2020 | 2 | 2020 |
| Design of an Artificial Peptide Inspired by Transmembrane Mitochondrial Protein for Escorting Exogenous DNA into the Mitochondria to Restore their Functions by Simultaneous … N Yoshinaga, T Miyamoto, M Odahara, N Takeda‐Kamiya, K Toyooka, ... Advanced Functional Materials 34 (8), 2306070, 2024 | 1 | 2024 |
Kazunori KataokaDirector General, Innovation Center of NanoMed; Professor Emeritus, Univ. TokyoVerified email at bmw.t.u-tokyo.ac.jp
