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Adam Offenbacher
Adam Offenbacher
Assistant Professor of Chemistry, East Carolina University
Verified email at ecu.edu
Title
Cited by
Cited by
Year
Understanding biological hydrogen transfer through the lens of temperature dependent kinetic isotope effects
JP Klinman, AR Offenbacher
Accounts of chemical research 51 (9), 1966-1974, 2018
1092018
pH-dependent cis→ trans isomerization rates for azobenzene dyes in aqueous solution
NJ Dunn, WH Humphries IV, AR Offenbacher, TL King, JA Gray
The Journal of Physical Chemistry A 113 (47), 13144-13151, 2009
942009
Origins of enzyme catalysis: Experimental findings for C–H activation, new models, and their relevance to prevailing theoretical constructs
JP Klinman, AR Offenbacher, S Hu
Journal of the American Chemical Society 139 (51), 18409-18427, 2017
632017
Hydrogen–deuterium exchange of lipoxygenase uncovers a relationship between distal, solvent exposed protein motions and the thermal activation barrier for catalytic proton …
AR Offenbacher, S Hu, EM Poss, CAM Carr, AD Scouras, DM Prigozhin, ...
ACS central science 3 (6), 570-579, 2017
592017
13C ENDOR Spectroscopy of Lipoxygenase–Substrate Complexes Reveals the Structural Basis for C–H Activation by Tunneling
M Horitani, AR Offenbacher, CAM Carr, T Yu, V Hoeke, GE Cutsail III, ...
Journal of the American Chemical Society 139 (5), 1984-1997, 2017
592017
Proton-coupled electron transfer and redox-active tyrosines: Structure and function of the tyrosyl radicals in ribonucleotide reductase and photosystem II
BA Barry, J Chen, J Keough, D Jenson, A Offenbacher, C Pagba
The journal of physical chemistry letters 3 (4), 543-554, 2012
492012
An intrinsically disordered photosystem II subunit, PsbO, provides a structural template and a sensor of the hydrogen-bonding network in photosynthetic water oxidation
AR Offenbacher, BC Polander, BA Barry
Journal of Biological Chemistry 288 (40), 29056-29068, 2013
372013
Redox-linked structural changes in ribonucleotide reductase
AR Offenbacher, IR Vassiliev, MR Seyedsayamdost, J Stubbe, BA Barry
Journal of the American Chemical Society 131 (22), 7496-7497, 2009
342009
Detecting and characterizing the kinetic activation of thermal networks in proteins: Thermal transfer from a distal, solvent-exposed loop to the active site in soybean lipoxygenase
JPT Zaragoza, A Nguy, N Minnetian, Z Deng, AT Iavarone, ...
The Journal of Physical Chemistry B 123 (41), 8662-8674, 2019
292019
Redox-active tyrosine residues in pentapeptides
IR Vassiliev, AR Offenbacher, BA Barry
The Journal of Physical Chemistry B 109 (48), 23077-23085, 2005
272005
Fatty acid allosteric regulation of CH activation in plant and animal lipoxygenases
AR Offenbacher, TR Holman
Molecules 25 (15), 3374, 2020
242020
The soybean lipoxygenase–substrate complex: Correlation between the properties of tunneling-ready states and ENDOR-detected structures of ground states
AR Offenbacher, A Sharma, PE Doan, JP Klinman, BM Hoffman
Biochemistry 59 (7), 901-910, 2020
242020
Biophysical characterization of a disabled double mutant of soybean lipoxygenase: the “undoing” of precise substrate positioning relative to metal cofactor and an identified …
S Hu, AR Offenbacher, EM Thompson, CL Gee, J Wilcoxen, CAM Carr, ...
Journal of the American Chemical Society 141 (4), 1555-1567, 2019
242019
Hydrogen–deuterium exchange reveals long-range dynamical allostery in soybean lipoxygenase
AR Offenbacher, AT Iavarone, JP Klinman
Journal of Biological Chemistry 293 (4), 1138-1148, 2018
242018
Redox-linked changes to the hydrogen-bonding network of ribonucleotide reductase β2
AR Offenbacher, EC Minnihan, JA Stubbe, BA Barry
Journal of the American Chemical Society 135 (17), 6380-6383, 2013
242013
Kinetic and structural investigations of novel inhibitors of human epithelial 15-lipoxygenase-2
WC Tsai, NC Gilbert, A Ohler, M Armstrong, S Perry, C Kalyanaraman, ...
Bioorganic & medicinal chemistry 46, 116349, 2021
202021
Redox-linked conformational control of proton-coupled electron transfer: Y122 in the ribonucleotide reductase β2 subunit
AR Offenbacher, LA Burns, CD Sherrill, BA Barry
The Journal of Physical Chemistry B 117 (28), 8457-8468, 2013
202013
Kinetic Characterization of the C–H Activation Step for the Lipoxygenase from the Pathogenic Fungus Magnaporthe oryzae: Impact of N-Linked Glycosylation
A Kostenko, K Ray, AT Iavarone, AR Offenbacher
Biochemistry 58 (29), 3193-3203, 2019
152019
Impact of local electrostatics on the redox properties of tryptophan radicals in azurin: Implications for redox-active tryptophans in proton-coupled electron transfer
KJ Tyson, AN Davis, JL Norris, LJ Bartolotti, EG Hvastkovs, ...
The Journal of Physical Chemistry Letters 11 (7), 2408-2413, 2020
142020
Temporal and spatial resolution of distal protein motions that activate hydrogen tunneling in soybean lipoxygenase
JPT Zaragoza, AR Offenbacher, S Hu, CL Gee, ZM Firestein, N Minnetian, ...
Proceedings of the National Academy of Sciences 120 (10), e2211630120, 2023
122023
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