Roberto Villasenor
Roberto Villasenor
Investigative Safety, Intracellular transport lab
Patvirtintas el. paštas
Signal processing by the endosomal system
R Villaseñor, Y Kalaidzidis, M Zerial
Current opinion in cell biology 39, 53-60, 2016
The SARS-CoV-2 main protease Mpro causes microvascular brain pathology by cleaving NEMO in brain endothelial cells
J Wenzel, J Lampe, H Müller-Fielitz, R Schuster, M Zille, K Müller, ...
Nature neuroscience 24 (11), 1522-1533, 2021
Intracellular transport and regulation of transcytosis across the blood–brain barrier
R Villaseñor, J Lampe, M Schwaninger, L Collin
Cellular and Molecular Life Sciences 76, 1081-1092, 2019
Cellular uptake mechanisms and endosomal trafficking of supercharged proteins
DB Thompson, R Villaseñor, BM Dorr, M Zerial, DR Liu
Chemistry & biology 19 (7), 831-843, 2012
Regulation of EGFR signal transduction by analogue-to-digital conversion in endosomes
R Villasenor, H Nonaka, P Del Conte-Zerial, Y Kalaidzidis, M Zerial
Elife 4, e06156, 2015
The mitogen-activated protein kinase p38 is involved in insect defense against Cry toxins from Bacillus thuringiensis
A Cancino-Rodezno, C Alexander, R Villaseñor, S Pacheco, H Porta, ...
Insect biochemistry and molecular biology 40 (1), 58-63, 2010
Region-specific permeability of the blood–brain barrier upon pericyte loss
R Villasenor, B Kuennecke, L Ozmen, M Ammann, C Kugler, F Grüninger, ...
Journal of Cerebral Blood Flow & Metabolism 37 (12), 3683-3694, 2017
Sorting tubules regulate blood-brain barrier transcytosis
R Villaseñor, M Schilling, J Sundaresan, Y Lutz, L Collin
Cell reports 21 (11), 3256-3270, 2017
A general theoretical framework to infer endosomal network dynamics from quantitative image analysis
L Foret, JE Dawson, R Villasenor, C Collinet, A Deutsch, L Brusch, ...
Current Biology 22 (15), 1381-1390, 2012
Trafficking of endogenous immunoglobulins by endothelial cells at the blood-brain barrier
R Villaseñor, L Ozmen, N Messaddeq, F Grüninger, H Loetscher, A Keller, ...
Scientific reports 6 (1), 1-10, 2016
Macropinocytosis of the PDGF β-receptor promotes fibroblast transformation by H-RasG12V
C Schmees, R Villasenor, W Zheng, H Ma, M Zerial, CH Heldin, ...
Molecular biology of the cell 23 (13), 2571-2582, 2012
Are biotransformation studies of therapeutic proteins needed? Scientific considerations and technical challenges
S Schadt, S Hauri, F Lopes, MR Edelmann, RF Staack, R Villaseñor, ...
Drug Metabolism and Disposition 47 (12), 1443-1456, 2019
Inhibition of EGF uptake by nephrotoxic antisense drugs in vitro and implications for preclinical safety profiling
A Moisan, M Gubler, JD Zhang, Y Tessier, KD Erichsen, S Sewing, ...
Molecular Therapy-Nucleic Acids 6, 89-105, 2017
Investigating receptor-mediated antibody transcytosis using blood–brain barrier organoid arrays
C Simonneau, M Duschmalé, A Gavrilov, N Brandenberg, S Hoehnel, ...
Fluids and Barriers of the CNS 18 (1), 1-17, 2021
Microphysiological neurovascular barriers to model the inner retinal microvasculature
TL Maurissen, G Pavlou, C Bichsel, R Villaseñor, RD Kamm, H Ragelle
Journal of Personalized Medicine 12 (2), 148, 2022
High-resolution confocal imaging of the blood-brain barrier: imaging, 3D reconstruction, and quantification of transcytosis
R Villaseñor, L Collin
JoVE (Journal of Visualized Experiments), e56407, 2017
High throughput blood-brain barrier organoid generation and assessment of receptor-mediated antibody transcytosis
E Kassianidou, C Simonneau, A Gavrilov, R Villaseñor
Bio-protocol 12 (8), e4399-e4399, 2022
Learning microscopic kinetic characteristic of endosomal network by quantitative analysis of snap-shot microscopy images
Y Kalaidzidis, L Foret, JE Dawson, R Villaseñor, F Jülicher, M Zerial
Proceedings of the International Conference on Bioinformatics …, 2013
Targeting neuronal lysosomal dysfunction caused by β-glucocerebrosidase deficiency with an enzyme-based brain shuttle construct
A Gehrlein, V Udayar, N Anastasi, ML Morella, I Ruf, D Brugger, ...
Nature Communications 14 (1), 2057, 2023
Regulation RTK signaling specificity by tuning early endosome distribution
Y Kalaidzidis, R Villaseñor, M Zerial
9th European Conference on Mathematical and Theoretical Biology, 2014
Sistema negali atlikti operacijos. Bandykite vėliau dar kartą.
Straipsniai 1–20