| Cobalt-catalyzed asymmetric hydrogenation of enamides enabled by single-electron reduction MR Friedfeld, H Zhong, RT Ruck, M Shevlin, PJ Chirik Science 360 (6391), 888-893, 2018 | 225 | 2018 |
| Asymmetric catalysis of hetero-ene reactions with tridentate Schiff base chromium (III) complexes RT Ruck, EN Jacobsen Journal of the American Chemical Society 124 (12), 2882-2883, 2002 | 197 | 2002 |
| Palladium‐Catalyzed Tandem Heck Reaction/C H Functionalization—Preparation of Spiro‐Indane‐Oxindoles RT Ruck, MA Huffman, MM Kim, M Shevlin, WV Kandur, IW Davies Angewandte Chemie 120 (25), 4789-4792, 2008 | 180 | 2008 |
| Selective Hydrogen Atom Abstraction through Induced Bond Polarization: Direct α‐Arylation of Alcohols through Photoredox, HAT, and Nickel Catalysis J Twilton, M Christensen, DA DiRocco, RT Ruck, IW Davies, ... Angewandte Chemie International Edition 57 (19), 5369-5373, 2018 | 168 | 2018 |
| A multifunctional catalyst that stereoselectively assembles prodrugs DA DiRocco, Y Ji, EC Sherer, A Klapars, M Reibarkh, J Dropinski, ... Science 356 (6336), 426-430, 2017 | 145 | 2017 |
| A concise synthesis of a β-lactamase inhibitor IK Mangion, RT Ruck, N Rivera, MA Huffman, M Shevlin Organic letters 13 (20), 5480-5483, 2011 | 139 | 2011 |
| Asymmetric Hetero‐Ene Reactions of Trimethylsilyl Enol Ethers Catalyzed by Tridentate Schiff Base Chromium(III) Complexes RT Ruck, EN Jacobsen Angewandte Chemie 115 (39), 4919-4922, 2003 | 89 | 2003 |
| Sulfoxonium ylide derived metal carbenoids in organic synthesis J Vaitla, A Bayer Synthesis 51 (03), 612-628, 2019 | 78 | 2019 |
| Rapid catalyst identification for the synthesis of the pyrimidinone core of HIV integrase inhibitors A Bellomo, N Celebi‐Olcum, X Bu, N Rivera, RT Ruck, CJ Welch, ... Angewandte Chemie-International Edition 51 (28), 6912, 2012 | 77 | 2012 |
| Carboamination: additions of imine C= N bonds across alkynes catalyzed by imidozirconium complexes RT Ruck, RL Zuckerman, SW Krska, RG Bergman Angewandte Chemie (International ed. in English) 43 (40), 5372, 2004 | 76 | 2004 |
| β-lactamase inhibitors TA Blizzard, H Chen, C Gude, JD Hermes, J Imbriglio, S Kim, JY Wu, ... US Patent 8,487,093, 2013 | 70 | 2013 |
| Green iodination of pyrazoles with iodine/hydrogen peroxide in water MM Kim, RT Ruck, D Zhao, MA Huffman Tetrahedron Letters 49 (25), 4026-4028, 2008 | 69 | 2008 |
| Rhodium-catalyzed asymmetric hydroamination of allyl amines EP Vanable, JL Kennemur, LA Joyce, RT Ruck, DM Schultz, KL Hull Journal of the American Chemical Society 141 (2), 739-742, 2019 | 65 | 2019 |
| A kinase-cGAS cascade to synthesize a therapeutic STING activator JA McIntosh, Z Liu, BM Andresen, NS Marzijarani, JC Moore, NM Marshall, ... Nature 603 (7901), 439-444, 2022 | 60 | 2022 |
| Ruthenium-catalyzed dynamic kinetic resolution asymmetric transfer hydrogenation of β-chromanones by an elimination-induced racemization mechanism ER Ashley, EC Sherer, B Pio, RK Orr, RT Ruck ACS Catalysis 7 (2), 1446-1451, 2017 | 54 | 2017 |
| Discovery of ruzasvir (MK-8408): a potent, pan-genotype HCV NS5A inhibitor with optimized activity against common resistance-associated polymorphisms L Tong, W Yu, L Chen, O Selyutin, MP Dwyer, AG Nair, R Mazzola, ... Journal of Medicinal Chemistry 60 (1), 290-306, 2017 | 49 | 2017 |
| Enantioselective Synthesis of α-Methyl-β-cyclopropyldihydrocinnamates M Christensen, A Nolting, M Shevlin, M Weisel, PE Maligres, J Lee, ... The Journal of Organic Chemistry 81 (3), 824-830, 2016 | 46 | 2016 |
| Zirconium-mediated conversion of amides to nitriles: a surprising additive effect RT Ruck, RG Bergman Angewandte Chemie (International ed. in English) 43 (40), 5375, 2004 | 42 | 2004 |
| Preparation of alkyl esters of n-protected oxo-azacycloalkylcarboxylic acids I Mangion, MA Huffman, RT Ruck, J Lynch, JYL Chung, B Marcune US Patent App. 13/266,871, 2012 | 41 | 2012 |
| Solvent perturbs the reactivity of tert-butylcarbene RT Ruck, M Jones Jr Tetrahedron letters 39 (16), 2277-2280, 1998 | 40 | 1998 |
