Yu (Brandon) Xia
Yu (Brandon) Xia
Professor of Bioengineering, McGill University
Verified email at - Homepage
Cited by
Cited by
A proteome-scale map of the human interactome network
T Rolland, M Taşan, B Charloteaux, SJ Pevzner, Q Zhong, N Sahni, S Yi, ...
Cell 159 (5), 1212-1226, 2014
A reference map of the human binary protein interactome
K Luck, DK Kim, L Lambourne, K Spirohn, BE Begg, W Bian, R Brignall, ...
Nature, 1-7, 2020
Annotation transfer between genomes: protein–protein interologs and protein–DNA regulogs
H Yu, NM Luscombe, HX Lu, X Zhu, Y Xia, JDJ Han, N Bertin, S Chung, ...
Genome research 14 (6), 1107-1118, 2004
Diverse cellular functions of the Hsp90 molecular chaperone uncovered using systems approaches
AJ McClellan, Y Xia, AM Deutschbauer, RW Davis, M Gerstein, J Frydman
Cell 131 (1), 121-135, 2007
Widespread Macromolecular Interaction Perturbations in Human Genetic Disorders
N Sahni, S Yi, M Taipale, JIF Bass, J Coulombe-Huntington, F Yang, ...
Cell 161 (3), 647-660, 2015
Widespread Expansion of Protein Interaction Capabilities by Alternative Splicing
X Yang, J Coulombe-Huntington, S Kang, GM Sheynkman, T Hao, ...
Cell 164 (4), 805-817, 2016
Relating three-dimensional structures to protein networks provides evolutionary insights
PM Kim, LJ Lu, Y Xia, MB Gerstein
Science 314 (5807), 1938, 2006
Defining the TRiC/CCT interactome links chaperonin function to stabilization of newly made proteins with complex topologies
AY Yam, Y Xia, HTJ Lin, A Burlingame, M Gerstein, J Frydman
Nature structural & molecular biology 15 (12), 1255-1262, 2008
Assessing the limits of genomic data integration for predicting protein networks
LJ Lu, Y Xia, A Paccanaro, H Yu, M Gerstein
Genome research 15 (7), 945-953, 2005
The role of disorder in interaction networks: a structural analysis
PM Kim, A Sboner, Y Xia, M Gerstein
Molecular Systems Biology 4 (1), 179, 2008
Genome-wide prioritization of disease genes and identification of disease-disease associations from an integrated human functional linkage network
B Linghu, ES Snitkin, Z Hu, Y Xia, C DeLisi
Genome Biol 10 (9), R91, 2009
Ab initio construction of protein tertiary structures using a hierarchical approach
Y Xia, ES Huang, M Levitt, R Samudrala
Journal of molecular biology 300 (1), 171-185, 2000
Structural determinants of protein evolution are context-sensitive at the residue level
EA Franzosa, Y Xia
Molecular biology and evolution 26 (10), 2387-2395, 2009
Analyzing cellular biochemistry in terms of molecular networks
Y Xia, H Yu, R Jansen, M Seringhaus, S Baxter, D Greenbaum, H Zhao, ...
Annual review of biochemistry 73 (1), 1051-1087, 2004
Use of thioredoxin as a reporter to identify a subset of Escherichia coli signal sequences that promote signal recognition particle-dependent translocation
D Huber, D Boyd, Y Xia, MH Olma, M Gerstein, J Beckwith
Journal of bacteriology 187 (9), 2983-2991, 2005
Ab initio protein structure prediction using a combined hierarchical approach
R Samudrala, Y Xia, E Huang, M Levitt
Proteins: Structure, Function, and Bioinformatics 37 (S3), 194-198, 1999
Structural principles within the human-virus protein-protein interaction network
EA Franzosa, Y Xia
Proceedings of the National Academy of Sciences 108 (26), 10538-10543, 2011
A proteome-wide fission yeast interactome reveals network evolution principles from yeasts to human
TV Vo, J Das, MJ Meyer, NA Cordero, N Akturk, X Wei, BJ Fair, ...
Cell 164 (1), 310-323, 2016
Simulating protein evolution in sequence and structure space
Y Xia, M Levitt
Current opinion in structural biology 14 (2), 202-207, 2004
A High-Resolution Genome-Wide CRISPR/Cas9 Viability Screen Reveals Structural Features and Contextual Diversity of the Human Cell-Essential Proteome
T Bertomeu, J Coulombe-Huntington, A Chatr-aryamontri, KG Bourdages, ...
Molecular and cellular biology 38 (1), e00302-17, 2018
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