Andy Thunnissen
Exploiting chemical libraries, structure, and genomics in the search for kinase inhibitors
NS Gray, L Wodicka, AMWH Thunnissen, TC Norman, S Kwon, ...
Science 281 (5376), 533-538, 1998
Inhibition of cyclin-dependent kinases, GSK-3β and CK1 by hymenialdisine, a marine sponge constituent
L Meijer, AMWH Thunnissen, AW White, M Garnier, M Nikolic, LH Tsai, ...
Chemistry & biology 7 (1), 51-63, 2000
Crystal Structures of the ATPase Subunit of the Glucose ABC Transporter from Sulfolobus solfataricus: Nucleotide-free and Nucleotide-bound Conformations
G Verdon, SV Albers, BW Dijkstra, AJM Driessen, AMWH Thunnissen
Journal of molecular biology 330 (2), 343-358, 2003
Doughnut-shaped structure of a bacterial muramidase revealed by X-ray crystallography
AMWH Thunnissen, AJ Dijkstra, KH Kalk, HJ Rozeboom, H Engel, W Keck, ...
Nature 367 (6465), 750-753, 1994
Subunit and chlorophyll organization of the plant photosystem II supercomplex
LS van Bezouwen, S Caffarri, RS Kale, R Kouřil, AMWH Thunnissen, ...
Nature Plants 3 (7), 1-11, 2017
Structure of the 70-kDa soluble lytic transglycosylase complexed with bulgecin A. Implications for the enzymic mechanism
AMWH Thunnissen, HJ Rozeboom, KH Kalk, BW Dijkstra
Biochemistry 34 (39), 12729-12737, 1995
High resolution crystal structures of the Escherichia coli lytic transglycosylase Slt70 and its complex with a peptidoglycan fragment
EJ Van Asselt, AMWH Thunnissen, BW Dijkstra
Journal of molecular biology 291 (4), 877-898, 1999
Structure of the transcriptional regulator LmrR and its mechanism of multidrug recognition
PK Madoori, H Agustiandari, AJM Driessen, AMWH Thunnissen
The EMBO journal 28 (2), 156-166, 2009
Formation of the productive ATP-Mg2+-bound dimer of GlcV, an ABC-ATPase from Sulfolobus solfataricus
G Verdon, SV Albers, N van Oosterwijk, BW Dijkstra, AJM Driessen, ...
Journal of molecular biology 334 (2), 255-267, 2003
An artificial heme enzyme for cyclopropanation reactions
L Villarino, KE Splan, E Reddem, L Alonso‐Cotchico, ...
Angewandte Chemie International Edition 57 (26), 7785-7789, 2018
The structural basis for peptide selection by the transport receptor OppA
RPA Berntsson, MK Doeven, F Fusetti, RH Duurkens, D Sengupta, ...
The EMBO journal 28 (9), 1332-1340, 2009
The adaptability of the active site of trypanosomal triosephosphate isomerase as observed in the crystal structures of three different complexes
MEM Noble, RK Wierenga, AM Lambeir, FR Opperdoes, ...
Proteins: Structure, Function, and Bioinformatics 10 (1), 50-69, 1991
The catalytic domain of a bacterial lytic transglycosylase defines a novel class of lysozymes
AMWH Thunnissen, NW Isaacs, BW Dijkstral
Proteins: Structure, Function, and Bioinformatics 22 (3), 245-258, 1995
Engineering methylaspartate ammonia lyase for the asymmetric synthesis of unnatural amino acids
H Raj, W Szymański, J De Villiers, HJ Rozeboom, VP Veetil, CR Reis, ...
Nature Chemistry 4 (6), 478-484, 2012
Using mutability landscapes of a promiscuous tautomerase to guide the engineering of enantioselective Michaelases
JY van der Meer, H Poddar, BJ Baas, Y Miao, M Rahimi, A Kunzendorf, ...
Nature communications 7 (1), 10911, 2016
Functional characterization of mutations in the myosin Vb gene associated with microvillus inclusion disease
AM Szperl, MR Golachowska, M Bruinenberg, R Prekeris, ...
Journal of pediatric gastroenterology and nutrition 52 (3), 307-313, 2011
Directed evolution of a designer enzyme featuring an unnatural catalytic amino acid
C Mayer, C Dulson, E Reddem, AMWH Thunnissen, G Roelfes
Angewandte Chemie International Edition 58 (7), 2083-2087, 2019
Crystal structure of MltA from Escherichia coli reveals a unique lytic transglycosylase fold
KE van Straaten, BW Dijkstra, W Vollmer, AMWH Thunnissen
Journal of molecular biology 352 (5), 1068-1080, 2005
Explaining operational instability of amine transaminases: substrate-induced inactivation mechanism and influence of quaternary structure on enzyme–cofactor intermediate stability
T Börner, S Rämisch, ER Reddem, S Bartsch, A Vogel, ...
Acs Catalysis 7 (2), 1259-1269, 2017
Robust ω-transaminases by computational stabilization of the subunit interface
Q Meng, N Capra, CM Palacio, E Lanfranchi, M Otzen, LZ Van Schie, ...
ACS catalysis 10 (5), 2915-2928, 2020
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Straipsniai 1–20