| High-affinity ligands of the colchicine domain in tubulin based on a structure-guided design O Bueno, J Estevez Gallego, S Martins, AE Prota, F Gago, ... Scientific reports 8 (1), 4242, 2018 | 49 | 2018 |
| Structural model for differential cap maturation at growing microtubule ends J Estévez-Gallego, F Josa-Prado, S Ku, RM Buey, FA Balaguer, AE Prota, ... Elife 9, e50155, 2020 | 46 | 2020 |
| Taxanes convert regions of perturbed microtubule growth into rescue sites A Rai, T Liu, S Glauser, EA Katrukha, J Estévez-Gallego, ... Nature Materials 19 (3), 355-365, 2020 | 46 | 2020 |
| Crystal structure of the cyclostreptin-tubulin adduct: implications for tubulin activation by taxane-site ligands FA Balaguer, T Mühlethaler, J Estévez-Gallego, E Calvo, ... International journal of molecular sciences 20 (6), 1392, 2019 | 28 | 2019 |
| Lattice defects induced by microtubule-stabilizing agents exert a long-range effect on microtubule growth by promoting catastrophes A Rai, T Liu, EA Katrukha, J Estévez-Gallego, SW Manka, I Paterson, ... Proceedings of the National Academy of Sciences 118 (51), e2112261118, 2021 | 23 | 2021 |
| Conformational mimetics of the α-methyl chalcone TUB091 binding tubulin: Design, synthesis and antiproliferative activity O Bueno, G Tobajas, E Quesada, J Estévez-Gallego, S Noppen, ... European Journal of Medicinal Chemistry 148, 337-348, 2018 | 17 | 2018 |
| Zampanolide binding to tubulin indicates cross-talk of taxane site with colchicine and nucleotide sites JJ Field, B Pera, JE Gallego, E Calvo, J Rodríguez-Salarichs, ... Journal of natural products 81 (3), 494-505, 2017 | 15 | 2017 |
| Structural insight into the stabilization of microtubules by taxanes AE Prota, D Lucena-Agell, Y Ma, J Estevez-Gallego, S Li, K Bargsten, ... Elife 12, e84791, 2023 | 14 | 2023 |
| Modification of C-seco taxoids through ring tethering and substituent replacement leading to effective agents against tumor drug resistance mediated by βIII-Tubulin and P … Y Tang, J Rodríguez-Salarichs, Y Zhao, P Cai, J Estévez-Gallego, ... European Journal of Medicinal Chemistry 137, 488-503, 2017 | 14 | 2017 |
| Targeting the colchicine site in tubulin through cyclohexanedione derivatives MD Canela, O Bueno, S Noppen, GS Calvo, JE Gallego, JF Díaz, ... RSC advances 6 (23), 19492-19506, 2016 | 14 | 2016 |
| Diphenyl ether derivatives occupy the expanded binding site of cyclohexanedione compounds at the colchicine site in tubulin by movement of the αT5 loop O Bueno, M Gargantilla, J Estévez-Gallego, S Martins, JF Díaz, ... European Journal of Medicinal Chemistry 171, 195-208, 2019 | 5 | 2019 |
| Chemical modulation of microtubule structure through the laulimalide/peloruside site J Estévez-Gallego, B Álvarez-Bernad, B Pera, C Wullschleger, O Raes, ... Structure 31 (1), 88-99. e5, 2023 | 2 | 2023 |
| Microtubule lattice defects promote catastrophes A Rai, T Liu, EA Katrukha, J Estévez-Gallego, I Paterson, JF Díaz, ... BioRxiv, 2021 | 2 | 2021 |
| Crystal structures of taxane-tubulin complexes: Implications for the mechanism of microtubule stabilization by Taxol AE Prota, D Lucena-Agell, Y Ma, J Estévez-Gallego, C Roca, ... | 1 | 2021 |
| Chemical modulation of microtubule structure as a tool to target different diseases J Estévez-Gallego, B Álvarez-Bernad, D Lucena-Agell, F Bonato, ... Grupo Especializado de Cristalografía y Crecimiento Cristalino, 2023 | | 2023 |
| On the Importance of the Thiazole Nitrogen in Epothilones: Semisynthesis and Microtubule-Binding Affinity of Deaza-Epothilone C A Edenharter, L Ryckewaert, D Cintulová, J Estévez-Gallego, JF Díaz, ... Chemistry 2 (2), 499-509, 2020 | | 2020 |
| Implications of the microtubule cap structure in the molecular mechanism of paclitaxel J Estévez Gallego Implications of the microtubule cap structure in the molecular mechanism of …, 2020 | | 2020 |
| Protein-ligand complex for structure-based design: impact on the affinity and antitumor activity of new tubulin ligands O Bueno, J Estévez-Gallego, S Martins, AE Prota, F Gago, ... | | 2018 |
| Author response: Structural model for differential cap maturation at growing microtubule ends J Estévez-Gallego, F Josa-Prado, S Ku, RM Buey, FA Balaguer, AE Prota, ... | | |
