Minimum quality threshold in pre-clinical sepsis studies (MQTiPSS): an international expert consensus initiative for improvement of animal modeling in sepsis MF Osuchowski, A Ayala, S Bahrami, M Bauer, M Boros, JM Cavaillon, ... Intensive care medicine experimental 6, 1-6, 2018 | 198 | 2018 |
Extracellular vesicles as markers and mediators in sepsis P Raeven, J Zipperle, S Drechsler Theranostics 8 (12), 3348, 2018 | 88 | 2018 |
PART I: MINIMUM QUALITY THRESHOLD IN PRE-CLINICAL SEPSIS STUDIES (MQTiPSS) FOR STUDY DESIGN AND HUMANE MODELING ENDPOINTS. B Zingarelli, CM Coopersmith, S Drechsler, P Efron, JC Marshall, ... Shock (Augusta, Ga.) 51 (1), 10, 2019 | 58 | 2019 |
Relationship between age/gender-induced survival changes and the magnitude of inflammatory activation and organ dysfunction in post-traumatic sepsis S Drechsler, K Weixelbaumer, P Raeven, M Jafarmadar, A Khadem, ... PloS one 7 (12), e51457, 2012 | 54 | 2012 |
Why do they die? Comparison of selected aspects of organ injury and dysfunction in mice surviving and dying in acute abdominal sepsis S Drechsler, KM Weixelbaumer, A Weidinger, P Raeven, A Khadem, ... Intensive care medicine experimental 3, 1-21, 2015 | 43 | 2015 |
Splenectomy modulates early immuno-inflammatory responses to trauma-hemorrhage and protects mice against secondary sepsis S Drechsler, J Zipperle, P Rademann, M Jafarmadar, A Klotz, S Bahrami, ... Scientific reports 8 (1), 1-12, 2018 | 41 | 2018 |
Mitochondria-targeted antioxidants SkQ1 and MitoTEMPO failed to exert a long-term beneficial effect in murine polymicrobial sepsis P Rademann, A Weidinger, S Drechsler, A Meszaros, J Zipperle, ... Oxidative medicine and cellular longevity 2017, 2017 | 39 | 2017 |
Estrus cycle status defined by vaginal cytology does not correspond to fluctuations of circulating estrogens in female mice KM Weixelbaumer, S Drechsler, P Wehrenpfennig, A Khadem, S Bahrami, ... Shock 41 (2), 145-153, 2014 | 20 | 2014 |
The fluctuations of leukocytes and circulating cytokines in septic humanized mice vary with outcome T Skirecki, S Drechsler, G Hoser, M Jafarmadar, K Siennicka, Z Pojda, ... Frontiers in Immunology 10, 1427, 2019 | 19 | 2019 |
Experimentally approaching the ICU: monitoring outcome-based responses in the two-hit mouse model of posttraumatic sepsis S Drechsler, KM Weixelbaumer, H Redl, M van Griensven, S Bahrami, ... Journal of Biomedicine and Biotechnology 2011, 2011 | 18 | 2011 |
With mouse age comes wisdom: A review and suggestions of relevant mouse models for age-related conditions S Drechsler, MA Lynch, S Novella, H González-Navarro, S Hecimovic, ... Mechanisms of Ageing and Development 160, 54-68, 2016 | 15 | 2016 |
Antimicrobial photodynamic therapy fighting polymicrobial infections – a journey from in vitro to in vivo L Karner, S Drechsler, M Metzger, A Hacobian, B Schädl, P Slezak, ... Photochemical & Photobiological Sciences 19, 1332-1343, 2020 | 14 | 2020 |
The matricellular “cysteine-rich protein 61” is released from activated platelets and increased in the circulation during experimentally induced sepsis CVB Hviid, JS Erdem, S Drechsler, K Weixelbaumer, MS Ahmed, ... Shock 41 (3), 233-240, 2014 | 12 | 2014 |
Systemic inhibition and liver‐specific over‐expression of PAI‐1 failed to improve survival in all‐inclusive populations or homogenous cohorts of CLP mice P Raeven, S Drechsler, KM Weixelbaumer, D Bastelica, F Peiretti, A Klotz, ... Journal of Thrombosis and Haemostasis 12 (6), 958-969, 2014 | 10 | 2014 |
A non-lethal traumatic/hemorrhagic insult strongly modulates the compartment-specific PAI-1 response in the subsequent polymicrobial sepsis P Raeven, A Salibasic, S Drechsler, KM Weixelbaumer, M Jafarmadar, ... PLoS One 8 (2), e55467, 2013 | 10 | 2013 |
Contamination of wounds with fecal bacteria in immuno-suppressed mice L Karner, S Drechsler, M Metzger, P Slezak, J Zipperle, G Pinar, ... Scientific Reports 10 (1), 11494, 2020 | 6 | 2020 |
Comparison of post-traumatic changes in circulating and bone marrow leukocytes between BALB/c and CD-1 mouse strains T Spenlingwimmer, J Zipperle, M Jafarmadar, MF Osuchowski, ... Plos one 14 (9), e0222594, 2019 | 6 | 2019 |
Cecal ligation and puncture S Drechsler, M Osuchowski Sepsis: Methods and Protocols, 1-8, 2021 | 5 | 2021 |
Mouse model of posttraumatic abdominal sepsis: survival advantage of females over males does not depend on the cecum size P Wehrenpfennig, S Drechsler, KM Weixelbaumer, S Bahrami, ... European Surgical Research 52 (1-2), 83-89, 2014 | 5 | 2014 |
An early myelosuppression in the acute mouse sepsis is partly outcome-dependent T Skirecki, S Drechsler, A Jeznach, G Hoser, M Jafarmadar, J Kawiak, ... Frontiers in Immunology 12, 708670, 2021 | 3 | 2021 |