Selection-free zinc-finger-nuclease engineering by context-dependent assembly (CoDA) JD Sander, EJ Dahlborg, MJ Goodwin, L Cade, F Zhang, D Cifuentes, ... Nature methods 8 (1), 67-69, 2011 | 789 | 2011 |
Improved somatic mutagenesis in zebrafish using transcription activator-like effector nucleases (TALENs) FE Moore, D Reyon, JD Sander, SA Martinez, JS Blackburn, C Khayter, ... PloS one 7 (5), e37877, 2012 | 214 | 2012 |
High-throughput cell transplantation establishes that tumor-initiating cells are abundant in zebrafish T-cell acute lymphoblastic leukemia ACH Smith, AR Raimondi, CD Salthouse, MS Ignatius, JS Blackburn, ... Blood, The Journal of the American Society of Hematology 115 (16), 3296-3303, 2010 | 149 | 2010 |
Optimized cell transplantation using adult rag2 mutant zebrafish Q Tang, NS Abdelfattah, JS Blackburn, JC Moore, SA Martinez, FE Moore, ... Nature methods 11 (8), 821-824, 2014 | 134 | 2014 |
In vivo imaging of tumor-propagating cells, regional tumor heterogeneity, and dynamic cell movements in embryonal rhabdomyosarcoma MS Ignatius, E Chen, NM Elpek, AZ Fuller, IM Tenente, R Clagg, S Liu, ... Cancer cell 21 (5), 680-693, 2012 | 127 | 2012 |
Clonal evolution enhances leukemia-propagating cell frequency in T cell acute lymphoblastic leukemia through Akt/mTORC1 pathway activation JS Blackburn, S Liu, JL Wilder, KP Dobrinski, R Lobbardi, FE Moore, ... Cancer cell 25 (3), 366-378, 2014 | 124 | 2014 |
Matrix metalloproteinase-1 and thrombin differentially activate gene expression in endothelial cells via PAR-1 and promote angiogenesis JS Blackburn, CE Brinckerhoff The American journal of pathology 173 (6), 1736-1746, 2008 | 120 | 2008 |
RNA interference inhibition of matrix metalloproteinase-1 prevents melanoma metastasis by reducing tumor collagenase activity and angiogenesis JS Blackburn, CH Rhodes, CI Coon, CE Brinckerhoff Cancer research 67 (22), 10849-10858, 2007 | 105 | 2007 |
A matrix metalloproteinase-1/protease activated receptor-1 signaling axis promotes melanoma invasion and metastasis JS Blackburn, I Liu, CI Coon, CE Brinckerhoff Oncogene 28 (48), 4237-4248, 2009 | 104 | 2009 |
Imaging tumour cell heterogeneity following cell transplantation into optically clear immune-deficient zebrafish Q Tang, JC Moore, MS Ignatius, IM Tenente, MN Hayes, EG Garcia, ... Nature communications 7 (1), 10358, 2016 | 89 | 2016 |
Notch signaling expands a pre-malignant pool of T-cell acute lymphoblastic leukemia clones without affecting leukemia-propagating cell frequency JS Blackburn, S Liu, DM Raiser, SA Martinez, H Feng, ND Meeker, ... Leukemia 26 (9), 2069-2078, 2012 | 86 | 2012 |
Matrix metalloproteinase and G protein coupled receptors: co-conspirators in the pathogenesis of autoimmune disease and cancer SM Eck, JS Blackburn, AC Schmucker, PS Burrage, CE Brinckerhoff Journal of Autoimmunity 33 (3-4), 214-221, 2009 | 74 | 2009 |
Single-cell transcriptional analysis of normal, aberrant, and malignant hematopoiesis in zebrafish FE Moore, EG Garcia, R Lobbardi, E Jain, Q Tang, JC Moore, M Cortes, ... Journal of Experimental Medicine 213 (6), 979-992, 2016 | 69 | 2016 |
High-throughput imaging of adult fluorescent zebrafish with an LED fluorescence macroscope JS Blackburn, S Liu, AR Raimondi, MS Ignatius, CD Salthouse, ... Nature protocols 6 (2), 229-241, 2011 | 60 | 2011 |
Zebrafish as a model to assess cancer heterogeneity, progression and relapse JS Blackburn, DM Langenau Disease models & mechanisms 7 (7), 755-762, 2014 | 58 | 2014 |
TOX regulates growth, DNA repair, and genomic instability in T-cell acute lymphoblastic leukemia R Lobbardi, J Pinder, B Martinez-Pastor, M Theodorou, JS Blackburn, ... Cancer discovery 7 (11), 1336-1353, 2017 | 57 | 2017 |
Targeting phosphatases of regenerating liver (PRLs) in cancer M Wei, KV Korotkov, JS Blackburn Pharmacology & therapeutics 190, 128-138, 2018 | 50 | 2018 |
Quantifying the frequency of tumor-propagating cells using limiting dilution cell transplantation in syngeneic zebrafish JS Blackburn, S Liu, DM Langenau JoVE (Journal of Visualized Experiments), e2790, 2011 | 37 | 2011 |
Drug screening of primary patient derived tumor xenografts in zebrafish MG Haney, LH Moore, JS Blackburn JoVE (Journal of Visualized Experiments), e60996, 2020 | 24 | 2020 |
Protein tyrosine phosphatase 4A3 (PTP4A3/PRL-3) drives migration and progression of T-cell acute lymphoblastic leukemia in vitro and in vivo M Wei, MG Haney, DR Rivas, JS Blackburn Oncogenesis 9 (1), 6, 2020 | 23 | 2020 |