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Jessica Blackburn
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Selection-free zinc-finger-nuclease engineering by context-dependent assembly (CoDA)
JD Sander, EJ Dahlborg, MJ Goodwin, L Cade, F Zhang, D Cifuentes, ...
Nature methods 8 (1), 67-69, 2011
7892011
Improved somatic mutagenesis in zebrafish using transcription activator-like effector nucleases (TALENs)
FE Moore, D Reyon, JD Sander, SA Martinez, JS Blackburn, C Khayter, ...
PloS one 7 (5), e37877, 2012
2142012
High-throughput cell transplantation establishes that tumor-initiating cells are abundant in zebrafish T-cell acute lymphoblastic leukemia
ACH Smith, AR Raimondi, CD Salthouse, MS Ignatius, JS Blackburn, ...
Blood, The Journal of the American Society of Hematology 115 (16), 3296-3303, 2010
1492010
Optimized cell transplantation using adult rag2 mutant zebrafish
Q Tang, NS Abdelfattah, JS Blackburn, JC Moore, SA Martinez, FE Moore, ...
Nature methods 11 (8), 821-824, 2014
1342014
In vivo imaging of tumor-propagating cells, regional tumor heterogeneity, and dynamic cell movements in embryonal rhabdomyosarcoma
MS Ignatius, E Chen, NM Elpek, AZ Fuller, IM Tenente, R Clagg, S Liu, ...
Cancer cell 21 (5), 680-693, 2012
1272012
Clonal evolution enhances leukemia-propagating cell frequency in T cell acute lymphoblastic leukemia through Akt/mTORC1 pathway activation
JS Blackburn, S Liu, JL Wilder, KP Dobrinski, R Lobbardi, FE Moore, ...
Cancer cell 25 (3), 366-378, 2014
1242014
Matrix metalloproteinase-1 and thrombin differentially activate gene expression in endothelial cells via PAR-1 and promote angiogenesis
JS Blackburn, CE Brinckerhoff
The American journal of pathology 173 (6), 1736-1746, 2008
1202008
RNA interference inhibition of matrix metalloproteinase-1 prevents melanoma metastasis by reducing tumor collagenase activity and angiogenesis
JS Blackburn, CH Rhodes, CI Coon, CE Brinckerhoff
Cancer research 67 (22), 10849-10858, 2007
1052007
A matrix metalloproteinase-1/protease activated receptor-1 signaling axis promotes melanoma invasion and metastasis
JS Blackburn, I Liu, CI Coon, CE Brinckerhoff
Oncogene 28 (48), 4237-4248, 2009
1042009
Imaging tumour cell heterogeneity following cell transplantation into optically clear immune-deficient zebrafish
Q Tang, JC Moore, MS Ignatius, IM Tenente, MN Hayes, EG Garcia, ...
Nature communications 7 (1), 10358, 2016
892016
Notch signaling expands a pre-malignant pool of T-cell acute lymphoblastic leukemia clones without affecting leukemia-propagating cell frequency
JS Blackburn, S Liu, DM Raiser, SA Martinez, H Feng, ND Meeker, ...
Leukemia 26 (9), 2069-2078, 2012
862012
Matrix metalloproteinase and G protein coupled receptors: co-conspirators in the pathogenesis of autoimmune disease and cancer
SM Eck, JS Blackburn, AC Schmucker, PS Burrage, CE Brinckerhoff
Journal of Autoimmunity 33 (3-4), 214-221, 2009
742009
Single-cell transcriptional analysis of normal, aberrant, and malignant hematopoiesis in zebrafish
FE Moore, EG Garcia, R Lobbardi, E Jain, Q Tang, JC Moore, M Cortes, ...
Journal of Experimental Medicine 213 (6), 979-992, 2016
692016
High-throughput imaging of adult fluorescent zebrafish with an LED fluorescence macroscope
JS Blackburn, S Liu, AR Raimondi, MS Ignatius, CD Salthouse, ...
Nature protocols 6 (2), 229-241, 2011
602011
Zebrafish as a model to assess cancer heterogeneity, progression and relapse
JS Blackburn, DM Langenau
Disease models & mechanisms 7 (7), 755-762, 2014
582014
TOX regulates growth, DNA repair, and genomic instability in T-cell acute lymphoblastic leukemia
R Lobbardi, J Pinder, B Martinez-Pastor, M Theodorou, JS Blackburn, ...
Cancer discovery 7 (11), 1336-1353, 2017
572017
Targeting phosphatases of regenerating liver (PRLs) in cancer
M Wei, KV Korotkov, JS Blackburn
Pharmacology & therapeutics 190, 128-138, 2018
502018
Quantifying the frequency of tumor-propagating cells using limiting dilution cell transplantation in syngeneic zebrafish
JS Blackburn, S Liu, DM Langenau
JoVE (Journal of Visualized Experiments), e2790, 2011
372011
Drug screening of primary patient derived tumor xenografts in zebrafish
MG Haney, LH Moore, JS Blackburn
JoVE (Journal of Visualized Experiments), e60996, 2020
242020
Protein tyrosine phosphatase 4A3 (PTP4A3/PRL-3) drives migration and progression of T-cell acute lymphoblastic leukemia in vitro and in vivo
M Wei, MG Haney, DR Rivas, JS Blackburn
Oncogenesis 9 (1), 6, 2020
232020
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