All-optical electrophysiology in mammalian neurons using engineered microbial rhodopsins DR Hochbaum, Y Zhao, SL Farhi, N Klapoetke, CA Werley, V Kapoor, ... Nature methods 11 (8), 825-833, 2014 | 797 | 2014 |
Optical recording of action potentials in mammalian neurons using a microbial rhodopsin JM Kralj, AD Douglass, DR Hochbaum, D Maclaurin, AE Cohen Nature Methods 9 (1), 90-95, 2011 | 533 | 2011 |
Electrical spiking in Escherichia coli probed with a fluorescent voltage-indicating protein JM Kralj, DR Hochbaum, AD Douglass, AE Cohen Science 333 (6040), 345, 2011 | 404 | 2011 |
Cell-free co-expression of functional membrane proteins and apolipoprotein, forming soluble nanolipoprotein particles JA Cappuccio, CD Blanchette, TA Sulchek, ES Arroyo, JM Kralj, AK Hinz, ... Molecular & Cellular Proteomics 7 (11), 2246-2253, 2008 | 149 | 2008 |
Cardiotoxicity screening with simultaneous optogenetic pacing, voltage imaging and calcium imaging GT Dempsey, KW Chaudhary, N Atwater, C Nguyen, BS Brown, ... Journal of pharmacological and toxicological methods 81, 240-250, 2016 | 142 | 2016 |
Voltage-gated calcium flux mediates Escherichia coli mechanosensation GN Bruni, RA Weekley, BJT Dodd, JM Kralj Proceedings of the National Academy of Sciences 114 (35), 9445-9450, 2017 | 123 | 2017 |
Screening fluorescent voltage indicators with spontaneously spiking HEK cells J Park, CA Werley, V Venkatachalam, JM Kralj, SD Dib-Hajj, SG Waxman, ... PloS one 8 (12), e85221, 2013 | 100 | 2013 |
Simultaneous mapping of membrane voltage and calcium in zebrafish heart in vivo reveals chamber-specific developmental transitions in ionic currents JH Hou, JM Kralj, AD Douglass, F Engert, AE Cohen Frontiers in physiology 5, 106165, 2014 | 97 | 2014 |
A glow-discharge approach for functionalization of carbon nanotubes BN Khare, M Meyyappan, J Kralj, P Wilhite, M Sisay, H Imanaka, ... Applied physics letters 81 (27), 5237-5239, 2002 | 92 | 2002 |
His-75 in proteorhodopsin, a novel component in light-driven proton translocation by primary pumps VB Bergo, OA Sineshchekov, JM Kralj, R Partha, EN Spudich, ... Journal of Biological Chemistry 284 (5), 2836, 2009 | 90 | 2009 |
Optogenetic probes for measuring membrane potential AE Cohen, JM Kralj, AD Douglass US Patent 9,057,734, 2015 | 87 | 2015 |
Membrane voltage dysregulation driven by metabolic dysfunction underlies bactericidal activity of aminoglycosides GN Bruni, JM Kralj Elife 9, e58706, 2020 | 69 | 2020 |
All-optical electrophysiology for high-throughput functional characterization of a human iPSC-derived motor neuron model of ALS E Kiskinis, JM Kralj, P Zou, EN Weinstein, H Zhang, K Tsioras, O Wiskow, ... Stem cell reports 10 (6), 1991-2004, 2018 | 61 | 2018 |
Raman spectroscopy reveals direct chromophore interactions in the Leu/Gln105 spectral tuning switch of proteorhodopsins JM Kralj, EN Spudich, JL Spudich, KJ Rothschild The Journal of Physical Chemistry B 112 (37), 11770-11776, 2008 | 54 | 2008 |
Conformational changes in the photocycle of Anabaena sensory rhodopsin VB Bergo, M Ntefidou, VD Trivedi, JJ Amsden, JM Kralj, KJ Rothschild, ... Journal of Biological Chemistry 281 (22), 15208, 2006 | 54 | 2006 |
Flash memory: photochemical imprinting of neuronal action potentials onto a microbial rhodopsin V Venkatachalam, D Brinks, D Maclaurin, D Hochbaum, J Kralj, AE Cohen Journal of the American Chemical Society 136 (6), 2529-2537, 2014 | 45 | 2014 |
Near-IR resonance Raman spectroscopy of archaerhodopsin 3: effects of transmembrane potential EC Saint Clair, JI Ogren, S Mamaev, D Russano, JM Kralj, KJ Rothschild The Journal of Physical Chemistry B 116 (50), 14592-14601, 2012 | 43 | 2012 |
Protonation state of Glu142 differs in the green-and blue-absorbing variants of proteorhodopsin JM Kralj, VB Bergo, JJ Amsden, EN Spudich, JL Spudich, KJ Rothschild Biochemistry 47 (11), 3447-3453, 2008 | 38 | 2008 |
Ultrasensitive Measurements of Microbial Rhodopsin Photocycles Using Photochromic FRET H Bayraktar, AP Fields, JM Kralj, JL Spudich, KJ Rothschild, AE Cohen Photochemistry and Photobiology, 2011 | 35 | 2011 |
Subpicosecond protein backbone changes detected during the green-absorbing proteorhodopsin primary photoreaction JJ Amsden, JM Kralj, LR Chieffo, X Wang, S Erramilli, EN Spudich, ... The Journal of Physical Chemistry B 111 (40), 11824-11831, 2007 | 34 | 2007 |