Stebėti
Neil Hodnett
Neil Hodnett
Patvirtintas el. paštas gsk.com
Pavadinimas
Cituota
Cituota
Metai
Testing Racemic Chiral Catalysts for Kinetic Resolution Potential.
B Dominguez, NS Hodnett, GC Lloyd-Jones
Angewandte Chemie (International ed. in English) 40 (22), 4289-4291, 2001
572001
High-throughput automated design of experiment (DoE) and kinetic modeling to aid in process development of an API
C Nunn, A DiPietro, N Hodnett, P Sun, KM Wells
Organic Process Research & Development 22 (1), 54-61, 2018
542018
A catalytic asymmetric bioorganic route to enantioenriched tetrahydro-and dihydropyranones
C Baker-Glenn, N Hodnett, M Reiter, S Ropp, R Ancliff, V Gouverneur
Journal of the American Chemical Society 127 (5), 1481-1486, 2005
462005
Kinetic model development for accelerated stability studies
D Clancy, N Hodnett, R Orr, M Owen, J Peterson
AAPS PharmSciTech 18 (4), 1158-1176, 2017
412017
Mechanistic implications of pseudo zero order kinetics in kinetic resolutions
DG Blackmond, NS Hodnett, GC Lloyd-Jones
Journal of the American Chemical Society 128 (23), 7450-7451, 2006
362006
Trimethylsilyldiazomethane
NS Hodnett
Synlett 2003 (13), 2095-2096, 2003
192003
Identification and characterisation of a salt form of Danirixin with reduced pharmacokinetic variability in patient populations
JC Bloomer, C Ambery, BE Miller, P Connolly, H Garden, N Henley, ...
European Journal of Pharmaceutics and Biopharmaceutics 117, 224-231, 2017
172017
ZUSCHRIFTEN-Testing Racemic Chiral Catalysts for Kinetic Resolution Potential
B Dominguez, NS Hodnett, GC Lloyd-Jones
Angewandte Chemie-German Edition 113 (22), 4419-4422, 2001
172001
The Even‐Handed Approach: Strategies for the Deployment of Racemic Chiral Catalysts
LA Evans, NS Hodnett, GC Lloyd‐Jones
Angewandte Chemie International Edition 51 (7), 1526-1533, 2012
112012
Development and Scale-Up of a Manufacturing Route for the Non-nucleoside Reverse Transcriptase Inhibitor GSK2248761A (IDX-899): Synthesis of an Advanced Key Chiral Intermediate
R Bellingham, G Borrett, G Bret, B Choudary, D Colclough, J Hayes, ...
Organic Process Research & Development 22 (2), 200-206, 2018
92018
Predictive distributions for constructing the ICH Q8 design space
JJ Peterson, M Yahyah, K Lief, N Hodnett
Comprehensive Quality by Design for Pharmaceutical Product Development and …, 2017
92017
Application of a system model for continuous manufacturing of an active pharmaceutical ingredient in an industrial environment
S Diab, G Bano, C Christodoulou, N Hodnett, A Benedetti, M Andersson, ...
Journal of Pharmaceutical Innovation 17 (4), 1333-1346, 2022
72022
Computer vision for non-contact monitoring of catalyst degradation and product formation kinetics
C Yan, M Cowie, C Howcutt, KMP Wheelhouse, NS Hodnett, M Kollie, ...
Chemical Science 14 (20), 5323-5331, 2023
62023
Development of a Scalable Process for the PPAR-α Agonist GW641597X Incorporating Baeyer–Villiger Chemistry and Retrospective ICH M7 Assessment
T Boyer, BM Choudary, AJ Edwards, E Etridge, S Etridge, A Giddings, ...
Organic Process Research & Development 24 (3), 371-386, 2020
42020
Computer vision for understanding catalyst degradation kinetics
C Yan, M Cowie, C Howcutt, K Wheelhouse, N Hodnett, M Kollie, ...
32022
Investigation of a Weak Temperature–Rate Relationship in the Carbamoylation of a Barbituric Acid Pharmaceutical Intermediate
AG O’Brien, YC Liu, MJ Hughes, JJ Lim, NS Hodnett, N Falco
The Journal of Organic Chemistry 84 (8), 4948-4952, 2019
32019
Development of an Efficient Manufacturing Process to GSK2248761A API
C Bret, E Smith, E Vit, JF Hayes, JD Hayler, A Ironmonger, D Pascoe, ...
Organic Process Research & Development 22 (2), 207-211, 2018
22018
Der “unparteiische” Ansatz: Strategien zur Entwicklung von racemischen chiralen Katalysatoren
LA Evans, NS Hodnett, GC Lloyd‐Jones
Angewandte Chemie 124 (7), 1556-1564, 2012
22012
Kinetic barriers to disproportionation of salts of weakly basic drugs
T Van Duong, S Diab, NS Hodnett, LS Taylor
Molecular Pharmaceutics 20 (8), 3886-3894, 2023
12023
The Integration of Drug Substance and Drug Product Manufacturing Models: The Missing Link for Model-based End-to-End Process Development
C Christodoulou, S Diab, G Bano, M Aroniada, N Hodnett, S Zomer
Computer Aided Chemical Engineering 52, 2101-2106, 2023
2023
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Straipsniai 1–20