| Subunit organization of the membrane-bound HIV-1 envelope glycoprotein trimer Y Mao, L Wang, C Gu, A Herschhorn, SH Xiang, H Haim, X Yang, ... Nature structural & molecular biology 19 (9), 893-899, 2012 | 214 | 2012 |
| Retroviral reverse transcriptases A Herschhorn, A Hizi Cellular and molecular life sciences 67, 2717-2747, 2010 | 167 | 2010 |
| Comparative analysis of the glycosylation profiles of membrane-anchored HIV-1 envelope glycoprotein trimers and soluble gp140 EP Go, A Herschhorn, C Gu, L Castillo-Menendez, S Zhang, Y Mao, ... Journal of virology 89 (16), 8245-8257, 2015 | 149 | 2015 |
| Molecular architecture of the uncleaved HIV-1 envelope glycoprotein trimer Y Mao, L Wang, C Gu, A Herschhorn, A Désormeaux, A Finzi, SH Xiang, ... Proceedings of the National Academy of Sciences 110 (30), 12438-12443, 2013 | 144 | 2013 |
| Crystal structures of trimeric HIV envelope with entry inhibitors BMS-378806 and BMS-626529 M Pancera, YT Lai, T Bylund, A Druz, S Narpala, S O'Dell, A Schön, ... Nature chemical biology 13 (10), 1115-1122, 2017 | 131 | 2017 |
| Release of gp120 restraints leads to an entry-competent intermediate state of the HIV-1 envelope glycoproteins A Herschhorn, X Ma, C Gu, JD Ventura, L Castillo-Menendez, B Melillo, ... MBio 7 (5), 10.1128/mbio. 01598-16, 2016 | 125 | 2016 |
| The β20–β21 of gp120 is a regulatory switch for HIV-1 Env conformational transitions A Herschhorn, C Gu, F Moraca, X Ma, M Farrell, AB Smith III, M Pancera, ... Nature communications 8 (1), 1049, 2017 | 84 | 2017 |
| A broad HIV-1 inhibitor blocks envelope glycoprotein transitions critical for entry A Herschhorn, C Gu, N Espy, J Richard, A Finzi, JG Sodroski Nature chemical biology 10 (10), 845-852, 2014 | 83 | 2014 |
| Peptides derived from the reverse transcriptase of human immunodeficiency virus type 1 as novel inhibitors of the viral integrase IO Gleenberg, O Avidan, Y Goldgur, A Herschhorn, A Hizi Journal of Biological Chemistry 280 (23), 21987-21996, 2005 | 65 | 2005 |
| The highly conserved layer-3 component of the HIV-1 gp120 inner domain is critical for CD4-required conformational transitions A Désormeaux, M Coutu, H Medjahed, B Pacheco, A Herschhorn, C Gu, ... Journal of virology 87 (5), 2549-2562, 2013 | 61 | 2013 |
| Inhibition of the activities of reverse transcriptase and integrase of human immunodeficiency virus type-1 by peptides derived from the homologous viral protein R (Vpr) IO Gleenberg, A Herschhorn, A Hizi Journal of molecular biology 369 (5), 1230-1243, 2007 | 55 | 2007 |
| Retroviral reverse transcriptases (other than those of HIV-1 and murine leukemia virus): a comparison of their molecular and biochemical properties A Hizi, A Herschhorn Virus research 134 (1-2), 203-220, 2008 | 52 | 2008 |
| De novo parallel design, synthesis and evaluation of inhibitors against the reverse transcriptase of human immunodeficiency virus type-1 and drug-resistant variants A Herschhorn, L Lerman, M Weitman, IO Gleenberg, A Nudelman, A Hizi Journal of medicinal chemistry 50 (10), 2370-2384, 2007 | 50 | 2007 |
| Lattice engineering enables definition of molecular features allowing for potent small-molecule inhibition of HIV-1 entry YT Lai, T Wang, S O’Dell, MK Louder, A Schön, CSF Cheung, GY Chuang, ... Nature communications 10 (1), 47, 2019 | 48 | 2019 |
| Residues in the gp41 ectodomain regulate HIV-1 envelope glycoprotein conformational transitions induced by gp120-directed inhibitors B Pacheco, N Alsahafi, O Debbeche, J Prévost, S Ding, JP Chapleau, ... Journal of virology 91 (5), 10.1128/jvi. 02219-16, 2017 | 48 | 2017 |
| Localization to detergent-resistant membranes and HIV-1 core entry inhibition correlate with HIV-1 restriction by SERINC5 B Schulte, A Selyutina, S Opp, A Herschhorn, JG Sodroski, M Pizzato, ... Virology 515, 52-65, 2018 | 46 | 2018 |
| Activation and inactivation of primary human immunodeficiency virus envelope glycoprotein trimers by CD4-mimetic compounds N Madani, AM Princiotto, C Zhao, F Jahanbakhshsefidi, M Mertens, ... Journal of virology 91 (3), 10.1128/jvi. 01880-16, 2017 | 43 | 2017 |
| Lineage-specific differences between human and simian immunodeficiency virus regulation of gp120 trimer association and CD4 binding A Finzi, B Pacheco, SH Xiang, M Pancera, A Herschhorn, L Wang, X Zeng, ... Journal of virology 86 (17), 8974-8986, 2012 | 37 | 2012 |
| SOSIP changes affect human immunodeficiency virus type 1 envelope glycoprotein conformation and CD4 engagement N Alsahafi, SP Anand, L Castillo-Menendez, MM Verly, H Medjahed, ... Journal of virology 92 (19), 10.1128/jvi. 01080-18, 2018 | 35 | 2018 |
| An inducible cell-cell fusion system with integrated ability to measure the efficiency and specificity of HIV-1 entry inhibitors A Herschhorn, A Finzi, DM Jones, JR Courter, A Sugawara, AB Smith III, ... PloS one 6 (11), e26731, 2011 | 34 | 2011 |
